Related references
Note: Only part of the references are listed.Phospholipase D1 and choline kinase-α are interactive targets in breast cancer
Mayur Gadiya et al.
CANCER BIOLOGY & THERAPY (2014)
The PRKCI and SOX2 Oncogenes Are Coamplified and Cooperate to Activate Hedgehog Signaling in Lung Squamous Cell Carcinoma
Verline Justilien et al.
CANCER CELL (2014)
Phospholipase D2 Mediates Survival Signaling through Direct Regulation of Akt in Glioblastoma Cells
Ronald C. Bruntz et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Pharmacological Inhibition of Phospholipase D Protects Mice From Occlusive Thrombus Formation and Ischemic Stroke-Brief Report
David Stegner et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2013)
Caffeic acid phenethyl ester downregulates phospholipase D1 via direct binding and inhibition of NFκB transactivation
Mi Hee Park et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2013)
Increased cell growth due to a new lipase-GEF (Phospholipase D2) fastly acting on Ras
Karen M. Henkels et al.
CELLULAR SIGNALLING (2013)
Macrophage migration arrest due to a winning balance of Rac2/Sp1 repression over β-catenin-induced PLD expression
Francis J. Speranza et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2013)
Development of Dual PLD1/2 and PLD2 Selective Inhibitors from a Common 1,3,8-Triazaspiro[4.5]decane Core: Discovery of ML298 and ML299 That Decrease Invasive Migration in U87-MG Glioblastoma Cells
Matthew C. O'Reilly et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
Phospholipase D1 Has a Pivotal Role in Interleukin-1β-Driven Chronic Autoimmune Arthritis through Regulation of NF-κB, Hypoxia-Inducible Factor 1α, and FoxO3a
Dong Woo Kang et al.
MOLECULAR AND CELLULAR BIOLOGY (2013)
Rebamipide abolishes Helicobacter pylori CagA-induced phospholipase D1 expression via inhibition of NFκB and suppresses invasion of gastric cancer cells
D. W. Kang et al.
ONCOGENE (2013)
Phospholipase D (PLD) drives cell invasion, tumor growth and metastasis in a human breast cancer xenograph model
K. M. Henkels et al.
ONCOGENE (2013)
Systematic Interrogation of 3q26 Identifies TLOC1 and SKIL as Cancer Drivers
Daniel Hagerstrand et al.
CANCER DISCOVERY (2013)
Loss of the Ceramide Transfer Protein Augments EGF Receptor Signaling in Breast Cancer
Johanna Heering et al.
CANCER RESEARCH (2012)
MicroRNA-203 leads to G1 phase cell cycle arrest in laryngeal carcinoma cells by directly targeting survivin
Ka Bian et al.
FEBS LETTERS (2012)
MicroRNA-203 suppresses cell proliferation and migration by targeting BIRC5 and LASP1 in human triple-negative breast cancer cells
Chen Wang et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2012)
PEA-15 potentiates H-Ras-mediated epithelial cell transformation through phospholipase D
F. J. Sulzmaier et al.
ONCOGENE (2012)
Key Roles for the Lipid Signaling Enzyme Phospholipase D1 in the Tumor Microenvironment During Tumor Angiogenesis and Metastasis
Qin Chen et al.
SCIENCE SIGNALING (2012)
Quercetin-induced downregulation of phospholipase D-1 inhibits proliferation and invasion in U87 glioma cells
Mi Hee Park et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
Phospholipase D Meets Wnt Signaling: A New Target for Cancer Therapy
Dong Woo Kang et al.
CANCER RESEARCH (2011)
Phospholipase D: Enzymology, Functionality, and Chemical Modulation
Paige E. Selvy et al.
CHEMICAL REVIEWS (2011)
IL-15 promotes osteoclastogenesis via the PLD pathway in rheumatoid arthritis
Mi Kyung Park et al.
IMMUNOLOGY LETTERS (2011)
Autoregulation of phospholipase D activity is coupled to selective induction of phospholipase D1 expression to promote invasion of breast cancer cells
Dong Woo Kang et al.
INTERNATIONAL JOURNAL OF CANCER (2011)
Phospholipase D Mediates Nutrient Input to Mammalian Target of Rapamycin Complex 1 (mTORC1)
Limei Xu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
PLD1 rather than PLD2 regulates phorbol-ester-, adhesion-dependent and Fcγ-receptor-stimulated ROS production in neutrophils
Laura J. Norton et al.
JOURNAL OF CELL SCIENCE (2011)
XPB, a subunit of TFIIH, is a target of the natural product triptolide
Denis V. Titov et al.
NATURE CHEMICAL BIOLOGY (2011)
Reversible bleb formation in mast cells stimulated with antigen is Ca2+/calmodulin-dependent and bleb size is regulated by ARF6
Yuhki Yanase et al.
BIOCHEMICAL JOURNAL (2010)
Platelet derived growth factor increases phospholipase D1 but not phospholipase D2 expression via NFκB signaling pathway and enhances invasion of breast cancer cells
Dong Woo Kang et al.
CANCER LETTERS (2010)
Phospholipase D1 Drives a Positive Feedback Loop to Reinforce the Wnt/β-Catenin/TCF Signaling Axis
Dong Woo Kang et al.
CANCER RESEARCH (2010)
Phospholipase D signaling pathway is involved in lung cancer-derived IL-8 increased osteoclastogenesis
Ya-Ling Hsu et al.
CARCINOGENESIS (2010)
Rebamipide-induced downregulation of phospholipase D inhibits inflammation and proliferation in gastric cancer cells
Dong Woo Kang et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2010)
Mammalian Target of Rapamycin (mTOR) and S6 Kinase Down-regulate Phospholipase D2 Basal Expression and Function
Farnaz Tabatabaian et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Phospholipase D2 Ablation Ameliorates Alzheimer's Disease-Linked Synaptic Dysfunction and Cognitive Deficits
Tiago Gil Oliveira et al.
JOURNAL OF NEUROSCIENCE (2010)
Phospholipase D1 Mediates TNFα-Induced Inflammation in a Murine Model of TNFα-Induced Peritonitis
Swaminathan Sethu et al.
PLOS ONE (2010)
Positive Feedback Regulation between Phospholipase D and Wnt Signaling Promotes Wnt-Driven Anchorage-Independent Growth of Colorectal Cancer Cells
Dong Woo Kang et al.
PLOS ONE (2010)
Impaired αIIbβ3 Integrin Activation and Shear-Dependent Thrombus Formation in Mice Lacking Phospholipase D1
Margitta Elvers et al.
SCIENCE SIGNALING (2010)
The phospholipase D1 pathway modulates macroautophagy
Claudia Dall'Armi et al.
NATURE COMMUNICATIONS (2010)
Overexpression of phospholipase D enhances matrix metalloproteinase-2 expression and glioma cell invasion via protein kinase C and protein kinase A/NF-κB/Sp1-mediated signaling pathways
Mi Hee Park et al.
CARCINOGENESIS (2009)
Phospholipase D1 is required for angiogenesis of intersegmental blood vessels in zebrafish
Xin-Xin I. Zeng et al.
DEVELOPMENTAL BIOLOGY (2009)
Triptolide-induced suppression of phospholipase D expression inhibits proliferation of MDA-MB-231 breast cancer cells
Dong Woo Kang et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2009)
What's positive about 'triple-negative' breast cancer?
Sara A. Hurvitz et al.
FUTURE ONCOLOGY (2009)
5-Fluoro-2-indolyl des-chlorohalopemide (FIPI), a Phospholipase D Pharmacological Inhibitor That Alters Cell Spreading and Inhibits Chemotaxis
Wenjuan Su et al.
MOLECULAR PHARMACOLOGY (2009)
Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness
Sarah A. Scott et al.
NATURE CHEMICAL BIOLOGY (2009)
SnoN overexpression is predictive of poor survival in patients with esophageal squamous cell carcinoma
Ichiro Akagi et al.
ANNALS OF SURGICAL ONCOLOGY (2008)
Use of gene expression profiles in cells of peripheral blood to identify new molecular markers of acute pancreatitis
Martin Bluth et al.
ARCHIVES OF SURGERY (2008)
Effects of active and inactive phospholipase D2 on signal transduction, adhesion, migration, invasion, and metastasis in EL4 lymphoma cells
Stewart M. Knoepp et al.
MOLECULAR PHARMACOLOGY (2008)
Linking epithelial polarity and carcinogenesis by multitasking Helicobacter pylori virulence factor CagA
M. Hatakeyama
ONCOGENE (2008)
Phorbol ester up-regulates phospholipase D1 but not phospholipase D2 expression through a PKC/Ras/ERK/NFκB-dependent pathway and enhances matrix metalloproteinase-9 secretion in colon cancer cells
Dong Woo Kang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Phospholipase D1 is associated with amyloid precursor protein in Alzheimer's disease
Jae-Kwang Jin et al.
NEUROBIOLOGY OF AGING (2007)
Optimization of halopemide for phospholipase D2 inhibition
Lauren Monovich et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2007)
Ewing's sarcoma fusion protein, EWS/Fli-1 and Fli-1 protein induce PLD2 but not PLD1 gene expression by binding to an ETS domain of 5′ promoter
R. Kikuchi et al.
ONCOGENE (2007)
Phospholipase D2-generated phosphatidic acid couples EGFR stimulation to Ras activation by Sos
Chen Zhao et al.
NATURE CELL BIOLOGY (2007)
A role for phospholipase D in Drosophila embryonic cellularization
Mary LaLonde et al.
BMC DEVELOPMENTAL BIOLOGY (2006)
Cyclic AMP-dependent and Epac-mediated activation of R-ras by G protein-coupled receptors leads to phospholipase D stimulation
Maider Lopez De Jesus et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
The Caenorhabditis elegans choline transporter CHO-1 sustains acetylcholine synthesis and motor function in an activity-dependent manner
Dawn Signor Matthies et al.
JOURNAL OF NEUROSCIENCE (2006)
Role of the CCAAT/enhancer-binding protein NFATc2 transcription factor cascade in the induction of secretory phospholipase A2
TTC Yang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Triptolide, an inhibitor of the human heat shock response that enhances stress-induced cell death
SD Westerheide et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Choline kinase: An important target for cancer
S Janardhan et al.
CURRENT MEDICINAL CHEMISTRY (2006)
Inhibition of platelet-derived growth factor-induced cell growth signaling by a short interfering RNA for EWS-Fli1 via down-regulation of phospholipase D2 in Ewing sarcoma cells
S Nozawa et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Phospholipase D2 stimulates integrin-mediated adhesion via phosphatidylinositol 4-phosphate 5-kinase Iγb
DJ Powner et al.
JOURNAL OF CELL SCIENCE (2005)
Acidic extracellular pH induces matrix metalloproteinase-9 expression in mouse metastatic melanoma cells through the phospholipase D-mitogen-activated protein kinase signaling
Y Kato et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Requirement of phospholipase D1 activity in H-RasV12-induced transformation
FG Buchanan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Alternative phospholipase D/mTOR survival signal in human breast cancer cells
YH Chen et al.
ONCOGENE (2005)
Oncogenic mechanisms of the Helicobacter pylori CagA protein
M Hatakeyama
NATURE REVIEWS CANCER (2004)
Phosphatidic acid-mediated mitogenic activation of mTOR signaling
YM Fang et al.
SCIENCE (2001)
Biology of EWS/ETS fusions in Ewing's family tumors
A Arvand et al.
ONCOGENE (2001)
Selective induction of phospholipase D1 in pathogen-activated human monocytes
M Locati et al.
BIOCHEMICAL JOURNAL (2001)
Inflammation and cancer: back to Virchow?
F Balkwill et al.
LANCET (2001)
Triptolide and chemotherapy cooperate in tumor cell apoptosis - A role for the p53 pathway
WT Chang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Phospholipase D and RalA cooperate with the epidermal growth factor receptor to transform 3Y1 rat fibroblasts
ZM Lu et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
Infections as a major preventable cause of human cancer
H Kuper et al.
JOURNAL OF INTERNAL MEDICINE (2000)
Share Paper
