Related references
Note: Only part of the references are listed.Trafficking in neurons: Searching for new targets for Alzheimer's disease future therapies
Stefano Musardo et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2013)
Loss of c-Jun N-terminal kinase-interacting protein-1 does not affect axonal transport of the amyloid precursor protein or A production
Alessio Vagnoni et al.
HUMAN MOLECULAR GENETICS (2013)
The Upside of APP at Synapses
Hyang-Sook Hoe et al.
CNS NEUROSCIENCE & THERAPEUTICS (2012)
Calsyntenin-1 mediates axonal transport of the amyloid precursor protein and regulates Aβ production
Alessio Vagnoni et al.
HUMAN MOLECULAR GENETICS (2012)
Membrane-Microdomain Localization of Amyloid β-Precursor Protein (APP) C-terminal Fragments Is Regulated by Phosphorylation of the Cytoplasmic Thr668 Residue
Takahide Matsushima et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
FBL2 Regulates Amyloid Precursor Protein (APP) Metabolism by Promoting Ubiquitination-Dependent APP Degradation and Inhibition of APP Endocytosis
Tomomichi Watanabe et al.
JOURNAL OF NEUROSCIENCE (2012)
Copper-dependent regulation of NMDA receptors by cellular prion protein: implications for neurodegenerative disorders
Peter K. Stys et al.
JOURNAL OF PHYSIOLOGY-LONDON (2012)
A Novel Role for Copper in Ras/Mitogen-Activated Protein Kinase Signaling
Michelle L. Turski et al.
MOLECULAR AND CELLULAR BIOLOGY (2012)
LDLR-related protein 10 (LRP10) regulates amyloid precursor protein (APP) trafficking and processing: evidence for a role in Alzheimer's disease
Julie Brodeur et al.
MOLECULAR NEURODEGENERATION (2012)
Culturing pyramidal neurons from the early postnatal mouse hippocampus and cortex
Gerard M. J. Beaudoin et al.
NATURE PROTOCOLS (2012)
Ubiquilin-1 regulates amyloid precursor protein maturation and degradation by stimulating K63-linked polyubiquitination of lysine 688
Amina El Ayadi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Trafficking and Proteolytic Processing of APP
Christian Haass et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2012)
Calsyntenin-1 shelters APP from proteolytic processing during anterograde axonal transport
Martin Steuble et al.
BIOLOGY OPEN (2012)
Copper Promotes the Trafficking of the Amyloid Precursor Protein
Karla M. Acevedo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
The Intracellular Threonine of Amyloid Precursor Protein That Is Essential for Docking of Pin1 Is Dispensable for Developmental Function
Alessia P. M. Barbagallo et al.
PLOS ONE (2011)
Amyloid Precursor Protein Is Trafficked and Secreted via Synaptic Vesicles
Teja W. Groemer et al.
PLOS ONE (2011)
GSK3 and Alzheimer's disease: facts and fiction
Anna Kremer et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2011)
GSK3: a multifaceted kinase in Wnt signaling
Dianqing Wu et al.
TRENDS IN BIOCHEMICAL SCIENCES (2010)
Phosphorylation regulates copper-responsive trafficking of the Menkes copper transporting P-type ATPase
Nicholas A. Veldhuis et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2009)
Paradoxical Condensation of Copper with Elevated β-Amyloid in Lipid Rafts under Cellular Copper Deficiency Conditions IMPLICATIONS FOR ALZHEIMER DISEASE
Ya Hui Hung et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
APP binds DR6 to trigger axon pruning and neuron death via distinct caspases
Anatoly Nikolaev et al.
NATURE (2009)
Evidence of calpain/cdk5 pathway inhibition by lithium in 3-nitropropionic acid toxicity in vivo and in vitro
N. Crespo-Biel et al.
NEUROPHARMACOLOGY (2009)
Intracellular copper deficiency increases amyloid-ß secretion by diverse mechanisms
Michael A. Cater et al.
BIOCHEMICAL JOURNAL (2008)
The role of GSK-3 in synaptic plasticity
S. Peineau et al.
BRITISH JOURNAL OF PHARMACOLOGY (2008)
Regulation of FE65 nuclear translocation and function by amyloid β-protein precursor in osmotically stressed cells
Tadashi Nakaya et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Regulation of Amyloid β-Protein Precursor by Phosphorylation and Protein Interactions
Toshiharu Suzuki et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
ADAM-10 over-expression increases cortical synaptogenesis
Karen F. S. Bell et al.
NEUROBIOLOGY OF AGING (2008)
Endocytosis is required for synaptic activity-dependent release of amyloid-β in vivo
John R. Cirrito et al.
NEURON (2008)
A critical function for β-amyloid precursor protein in neuronal migration revealed by In Utero RNA interference
Tracy L. Young-Pearse et al.
JOURNAL OF NEUROSCIENCE (2007)
The amyloid-β precursor protein is phosphorylated via distinct pathways during differentiation, mitosis, stress, and degeneration
Zoia Muresan et al.
MOLECULAR BIOLOGY OF THE CELL (2007)
Phosphorylation of APP695 at Thr668 decreases γ-cleavage and extracellular Aβ
Christine Feyt et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
GSK3 alpha and GSK3 beta are necessary for axon formation
Juan Jose Garrido et al.
FEBS LETTERS (2007)
Regulation and function of glycogen synthase kinase-3 isoforms in neuronal survival
Min-Huei Liang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Physiological Mouse Brain Aβ Levels Are Not Related to the Phosphorylation State of Threonine-668 of Alzheimer's APP
Yoshitake Sano et al.
PLOS ONE (2006)
Keratinocytes from APP/APLP2-deficient mice are impaired in proliferation, adhesion and migration in vitro
Christina Siemes et al.
EXPERIMENTAL CELL RESEARCH (2006)
Phosphorylation of amyloid precursor protein (APP) at Thr668 regulates the nuclear translocation of the APP intracellular domain and induces neurodegeneration
Keun-A Chang et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
AMP-activated protein kinase (AMPK) activating agents cause dephosphorylation of Akt and glycogen synthase kinase-3
Taj D. King et al.
BIOCHEMICAL PHARMACOLOGY (2006)
Culturing hippocampal neurons
Stefanie Kaech et al.
NATURE PROTOCOLS (2006)
Subcellular trafficking of the amyloid precursor protein gene family and its pathogenic role in Alzheimer's disease
Stefan Kins et al.
NEURODEGENERATIVE DISEASES (2006)
Synaptic activity regulates interstitial fluid amyloid-β levels in vivo
JR Cirrito et al.
NEURON (2005)
Coordinated transport of phosphorylated amyloid-β precursor protein and c-Jun NH2-terminal kinase-interacting protein-1
Z Muresan et al.
JOURNAL OF CELL BIOLOGY (2005)
Physiological regulation of the β-amyloid precursor protein signaling domain by c-Jun N-terminal kinase JNK3 during neuronal differentiation
WT Kimberly et al.
JOURNAL OF NEUROSCIENCE (2005)
c-Jun NH2-terminal kinase-interacting protein-3 facilitates phosphorylation and controls localization of amyloid-β precursor protein
Z Muresan et al.
JOURNAL OF NEUROSCIENCE (2005)
Implication of cyclin-dependent kinase 5 in the neuroprotective properties of lithium
EG Jorda et al.
NEUROSCIENCE (2005)
Copper stimulates trafficking of a distinct pool of the Menkes copper ATPase (ATP7A) to the plasma membrane and diverts it into a rapid recycling pool
L Pase et al.
BIOCHEMICAL JOURNAL (2004)
A phosphorylated, carboxy-terminal fragment of β-amyloid precursor protein localizes to the splicing factor compartment
Z Muresan et al.
HUMAN MOLECULAR GENETICS (2004)
Clioquinol mediates copper uptake and counteracts copper efflux activities of the amyloid precursor protein of Alzheimer's disease
C Treiber et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Signals regulating trafficking of Menkes (MNK; ATP7A) copper-translocating P-type ATPase in polarized MDCK cells
M Greenough et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2004)
APP processing is regulated by cytoplasmic phosphorylation
MS Lee et al.
JOURNAL OF CELL BIOLOGY (2003)
Regulation of amyloid precursor protein (APP) phosphorylation and processing by p35.Cdk5 and p25/Cdk5
F Liu et al.
FEBS LETTERS (2003)
A scaffold protein JIP-1b enhances amyloid precursor protein phosphorylation by JNK and its association with kinesin light chain 1
H Inomata et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Overexpression of Alzheimer's disease amyloid-β opposes the age-dependent elevations of brain copper and iron
CJ Maynard et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Interaction of Alzheimer's β-amyloid precursor family proteins with scaffold proteins of the JNK signaling cascade
H Taru et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Phosphorylation of thr(668) in the cytoplasmic domain of the Alzheimer's disease amyloid precursor protein by stress-activated protein kinase 1b (Jun N-terminal kinase-3)
CL Standen et al.
JOURNAL OF NEUROCHEMISTRY (2001)
Selective small-molecule inhibitors of glycogen synthase kinase-3 activity protect primary neurones from death
DAE Cross et al.
JOURNAL OF NEUROCHEMISTRY (2001)
Phosphorylation-induced structural changes in the amyloid precursor protein cytoplasmic tail detected by NMR
TA Ramelot et al.
JOURNAL OF MOLECULAR BIOLOGY (2001)
Decreased nuclear β-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3β conditional transgenic mice
JJ Lucas et al.
EMBO JOURNAL (2001)
Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription
MP Coghlan et al.
CHEMISTRY & BIOLOGY (2000)
Axonal membrane proteins are transported in distinct carriers: A two-color video microscopy study in cultured hippocampal neurons
C Kaether et al.
MOLECULAR BIOLOGY OF THE CELL (2000)
Neuron-specific phosphorylation of Alzheimer's beta-amyloid precursor protein by cyclin-dependent kinase 5
K Iijima et al.
JOURNAL OF NEUROCHEMISTRY (2000)