Related references
Note: Only part of the references are listed.PKM2 Isoform-Specific Deletion Reveals a Differential Requirement for Pyruvate Kinase in Tumor Cells
William J. Israelsen et al.
CELL (2013)
Insulin enhances metabolic capacities of cancer cells by dual regulation of glycolytic enzyme pyruvate kinase M2
Mohd Askandar Iqbal et al.
MOLECULAR CANCER (2013)
Pyruvate Kinase M2: Multiple Faces for Conferring Benefits on Cancer Cells
Mayumi Tamada et al.
CLINICAL CANCER RESEARCH (2012)
Pyruvate Kinase M2 Regulates Gene Transcription by Acting as a Protein Kinase
Xueliang Gao et al.
MOLECULAR CELL (2012)
Rocking cell metabolism: revised functions of the key glycolytic regulator PKM2 in cancer
Barbara Chaneton et al.
TRENDS IN BIOCHEMICAL SCIENCES (2012)
Emerging roles of PKM2 in cell metabolism and cancer progression
Weibo Luo et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2012)
Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation
Sophia Y. Lunt et al.
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 27 (2011)
Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1
Weibo Luo et al.
CELL (2011)
Acetylation Targets the M2 Isoform of Pyruvate Kinase for Degradation through Chaperone-Mediated Autophagy and Promotes Tumor Growth
Lei Lv et al.
MOLECULAR CELL (2011)
Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth
Qian Sun et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses
Dimitrios Anastasiou et al.
SCIENCE (2011)
Regulation of cancer cell metabolism
Rob A. Cairns et al.
NATURE REVIEWS CANCER (2011)
Crystal structure of the ALK (anaplastic lymphoma kinase) catalytic domain
Christian C. Lee et al.
BIOCHEMICAL JOURNAL (2010)
Dominant Negative Mutations Affect Oligomerization of Human Pyruvate Kinase M2 Isozyme and Promote Cellular Growth and Polyploidy
Vibhor Gupta et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Dominant-negative Effects of COL7A1 Mutations Can be Rescued by Controlled Overexpression of Normal Collagen VII
Anja Fritsch et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Differential Behavior of Missense Mutations in the Intersubunit Contact Domain of the Human Pyruvate Kinase M2 Isozyme
Kamal Akhtar et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Anchorage-independent cell growth signature identifies tumors with metastatic potential
S. Mori et al.
ONCOGENE (2009)
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
Matthew G. Vander Heiden et al.
SCIENCE (2009)
Tyrosine Phosphorylation Inhibits PKM2 to Promote the Warburg Effect and Tumor Growth
Taro Hitosugi et al.
SCIENCE SIGNALING (2009)
Regulation of M2-type pyruvate kinase mediated by the high-affinity IgE receptors is required for mast cell degranulation
H. Ryu et al.
BRITISH JOURNAL OF PHARMACOLOGY (2008)
Brick by brick: metabolism and tumor cell growth
Ralph J. DeBerardinis et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2008)
Pyruvate kinase M2 is a phosphotyrosine-binding protein
Heather R. Christofk et al.
NATURE (2008)
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
Heather R. Christofk et al.
NATURE (2008)
A therapeutic target for prostate cancer based on angiogenin-stimulated angiogenesis and cancer cell proliferation
Norie Yoshioka et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Pyruvate kinase type M2 and its role in tumor growth and spreading
S Mazurek et al.
SEMINARS IN CANCER BIOLOGY (2005)
Dominant negative effect of novel mutations in pyruvate kinase-M2
M Anitha et al.
DNA AND CELL BIOLOGY (2004)
Why do cancers have high aerobic glycolysis?
RA Gatenby et al.
NATURE REVIEWS CANCER (2004)
Effect of treatment sequence with radiotherapy and the antiestrogen EM 800 on the growth of ZR 75 1 human mammary carcinoma in nude mice
M Gutman et al.
INTERNATIONAL JOURNAL OF CANCER (2003)