Related references
Note: Only part of the references are listed.Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling
Jisun Lee et al.
BIOCHEMICAL JOURNAL (2012)
Leucine-rich repeat kinase 2 regulates autophagy through a calcium-dependent pathway involving NAADP
Patricia Gomez-Suaga et al.
HUMAN MOLECULAR GENETICS (2012)
Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice
Kelvin C. Luk et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2012)
Deficiency of ATP13A2 Leads to Lysosomal Dysfunction, α-Synuclein Accumulation, and Neurotoxicity
Marija Usenovic et al.
JOURNAL OF NEUROSCIENCE (2012)
p62/SQSTM1-Dependent Autophagy of Lewy Body-Like α-Synuclein Inclusions
Yoshihisa Watanabe et al.
PLOS ONE (2012)
Pathological α-Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice
Kelvin C. Luk et al.
SCIENCE (2012)
p62, Ref(2)P and ubiquitinated proteins are conserved markers of neuronal aging, aggregate formation and progressive autophagic defects
Bryan J. Bartlett et al.
AUTOPHAGY (2011)
Rapamycin treatment augments motor neuron degeneration in SOD1G93A mouse model of amyotrophic lateral sclerosis
Xiaojie Zhang et al.
AUTOPHAGY (2011)
Aggregation of α-Synuclein in S. cerevisiae is Associated with Defects in Endosomal Trafficking and Phospholipid Biosynthesis
James H. Soper et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2011)
Localization of MAP1-LC3 in Vulnerable Neurons and Lewy Bodies in Brains of Patients With Dementia With Lewy Bodies
Shinji Higashi et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2011)
Distinct Roles In Vivo for the Ubiquitin-Proteasome System and the Autophagy-Lysosomal Pathway in the Degradation of α-Synuclein
Darius Ebrahimi-Fakhari et al.
JOURNAL OF NEUROSCIENCE (2011)
Fighting neurodegeneration with rapamycin: mechanistic insights
Jordi Bove et al.
NATURE REVIEWS NEUROSCIENCE (2011)
Exogenous α-Synuclein Fibrils Induce Lewy Body Pathology Leading to Synaptic Dysfunction and Neuron Death
Laura A. Volpicelli-Daley et al.
NEURON (2011)
Parkinson's disease involves autophagy and abnormal distribution of cathepsin L
Lingyun Li et al.
NEUROSCIENCE LETTERS (2011)
Methods in Mammalian Autophagy Research
Noboru Mizushima et al.
CELL (2010)
The Parkinson-associated protein PINK1 interacts with Beclin1 and promotes autophagy
S. Michiorri et al.
CELL DEATH AND DIFFERENTIATION (2010)
Nix is a selective autophagy receptor for mitochondrial clearance
Ivana Novak et al.
EMBO REPORTS (2010)
α-Synuclein impairs macroautophagy: implications for Parkinson's disease
Ashley R. Winslow et al.
JOURNAL OF CELL BIOLOGY (2010)
Cell-Produced α-Synuclein Is Secreted in a Calcium-Dependent Manner by Exosomes and Impacts Neuronal Survival
Evangelia Emmanouilidou et al.
JOURNAL OF NEUROSCIENCE (2010)
Are synucleinopathies prion-like disorders?
Elodie Angot et al.
LANCET NEUROLOGY (2010)
Autophagy gone awry in neurodegenerative diseases
Esther Wong et al.
NATURE NEUROSCIENCE (2010)
Prion-like transmission of protein aggregates in neurodegenerative diseases
Patrik Brundin et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
In search of an autophagomometer
David C. Rubinsztein et al.
AUTOPHAGY (2009)
Rapamycin and mTOR-independent autophagy inducers ameliorate toxicity of polyglutamine-expanded huntingtin and related proteinopathies
S. Sarkar et al.
CELL DEATH AND DIFFERENTIATION (2009)
Nutrient Deprivation Induces Neuronal Autophagy and Implicates Reduced Insulin Signaling in Neuroprotective Autophagy Activation
Jessica E. Young et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Inhibition of Autophagy Induction Delays Neuronal Cell Loss Caused by Dysfunctional ESCRT-III in Frontotemporal Dementia
Jin-A Lee et al.
JOURNAL OF NEUROSCIENCE (2009)
Exogenous α-synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells
Kelvin C. Luk et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Neurodegenerative lysosomal disorders - A continuum from development to late age
Ralph A. Nixon et al.
AUTOPHAGY (2008)
Autophagy-mediated clearance of aggresomes is not a universal phenomenon
Esther S. P. Wong et al.
HUMAN MOLECULAR GENETICS (2008)
Autophagy induction and autophagosome clearance in neurons: Relationship to autophagic pathology in Alzheimer's disease
Barry Boland et al.
JOURNAL OF NEUROSCIENCE (2008)
An Atg4B Mutant Hampers the Lipidation of LC3 Paralogues and Causes Defects in Autophagosome Closure
Naonobu Fujita et al.
MOLECULAR BIOLOGY OF THE CELL (2008)
Misfolded proteins partition between two distinct quality control compartments
Daniel Kaganovich et al.
NATURE (2008)
The Parkinson's disease protein α-synuclein disrupts cellular Rab homeostasis
Aaron D. Gitler et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Autophagosome formation: Core machinery and adaptations
Zhiping Xie et al.
NATURE CELL BIOLOGY (2007)
The Lewy body in Parkinson's disease:: Molecules implicated in the formation and degradation of α-synuclein aggregates
Koichi Wakabayashi et al.
NEUROPATHOLOGY (2007)
Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3
Shunsuke Kimura et al.
AUTOPHAGY (2007)
p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy
Serhiy Pankiv et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Methods for monitoring autophagy from yeast to human
Daniel J. Klionsky et al.
AUTOPHAGY (2007)
Autophagosome-lysosome fusion depends on th pH in acidic compartments in CHO cells
Akinori Kawai et al.
AUTOPHAGY (2007)
Autophagy is activated for cell survival after endoplasmic reticulum stress
Maiko Ogata et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
The roles of intracellular protein-degradation pathways in neurodegeneration
David C. Rubinsztein
NATURE (2006)
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
Taichi Hara et al.
NATURE (2006)
Loss of autophagy in the central nervous system causes neurodegeneration in mice
Masaaki Komatsu et al.
NATURE (2006)
p62/SQSTM1 - A missing link between protein aggregates and the autophagy machinery
Geir Bjorkoy et al.
AUTOPHAGY (2006)
Maturation of autophagic vacuoles in mammalian cells
Eeva-Liisa Eskelinen
AUTOPHAGY (2005)
Gene expression profiles in HEK-293 cells with low or high store-operated calcium entry: can regulatory as well as regulated genes be identified?
TK Zagranichnaya et al.
PHYSIOLOGICAL GENOMICS (2005)
The new mutation, E46K, of α-synuclein causes Parkinson and Lewy body dementia
JJ Zarranz et al.
ANNALS OF NEUROLOGY (2004)
Protein folding, misfolding, and aggregation. formation of inclusion bodies and aggresomes
KA Markossian et al.
BIOCHEMISTRY-MOSCOW (2004)
Impaired degradation of mutant α-synuclein by chaperone-mediated autophagy
AM Cuervo et al.
SCIENCE (2004)
The cell biology of lysosomal storage disorders
AH Futerman et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2004)
Processing and activation of latent heparanase occurs in lysosomes
A Zetser et al.
JOURNAL OF CELL SCIENCE (2004)
The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress
Y Kawaguchi et al.
CELL (2003)
A rapid cellular FRET assay of polyglutamine aggregation identifies a novel inhibitor
SK Pollitt et al.
NEURON (2003)
α-synuclein locus triplication causes Parkinson's disease
AB Singleton et al.
SCIENCE (2003)
α-synuclein is degraded by both autophagy and the proteasome
JL Webb et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy
B Ravikumar et al.
HUMAN MOLECULAR GENETICS (2002)
Formation and removal of α-synuclein aggregates in cells exposed to mitochondrial inhibitors
HJ Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
p62 is a common component of cytoplasmic inclusions in protein aggregation diseases
K Zatloukal et al.
AMERICAN JOURNAL OF PATHOLOGY (2002)
The mitochondrial permeability transition initiates autophagy in rat hepatocytes
SP Elmore et al.
FASEB JOURNAL (2001)
Synucleinopathies - Clinical and pathological implications
JE Galvin et al.
ARCHIVES OF NEUROLOGY (2001)
A hydrophobic stretch of 12 amino acid residues in the middle of α-synuclein is essential for filament assembly
BI Giasson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
alpha-synuclein-enhanced green fluorescent protein fusion proteins form proteasome sensitive inclusions in primary neurons
PJ McLean et al.
NEUROSCIENCE (2001)
Aggresomes, inclusion bodies and protein aggregation
RR Kopito
TRENDS IN CELL BIOLOGY (2000)
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
Y Kabeya et al.
EMBO JOURNAL (2000)
Oxidative stress and genetics in the pathogenesis of Parkinson's disease
Y Zhang et al.
NEUROBIOLOGY OF DISEASE (2000)
Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system
A Abeliovich et al.
NEURON (2000)