Related references
Note: Only part of the references are listed.Systemic and Vascular Oxidation Limits the Efficacy of Oral Tetrahydrobiopterin Treatment in Patients With Coronary Artery Disease
Colin Cunnington et al.
CIRCULATION (2012)
Nitric oxide synthases: regulation and function
Ulrich Foerstermann et al.
EUROPEAN HEART JOURNAL (2012)
Tetrahydrobiopterin analogues with NO-dependent pulmonary vasodilator properties
Suma P. Kunuthur et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2011)
Ratio of 5,6,7,8- tetrahydrobiopterin to 7,8- dihydrobiopterin in endothelial cells determines glucose- elicited changes in NO vs. superoxide production by eNOS (vol 294, H1530, 2008)
M. J. Crabtree et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2010)
Quantitative Regulation of Intracellular Endothelial Nitric-oxide Synthase (eNOS) Coupling by Both Tetrahydrobiopterin-eNOS Stoichiometry and Biopterin Redox Status INSIGHTS FROM CELLS WITH TET-REGULATED GTP CYCLOHYDROLASE I EXPRESSION
Mark J. Crabtree et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Ratio of 5,6,7,8-tetrahydrobiopterin to 7,8-dihydrobiopterin in endothelial cells determines glucose-elicited changes in NO vs. superoxide production by eNOS
Mark J. Crabtree et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2008)
Radiochemical HPLC detection of arginine metabolism: Measurement of nitric oxide synthesis and arginase activity in vascular tissue
Joseph P. de Bono et al.
NITRIC OXIDE-BIOLOGY AND CHEMISTRY (2007)
Endothelial nitric oxide synthase dysfunction in diabetic mice: importance of tetrahydrobiopterin in eNOS dimerisation
S Cai et al.
DIABETOLOGIA (2005)
Detection and characterization of the product of hydroethidine and intracellular superoxide by HPLC and limitations of fluorescence
HT Zhao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Regulation of endothelial nitric oxide synthase by tetrahydrobiopterin in vascular disease
NJ Alp et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2004)
Increased endothelial tetrahydrobiopterin synthesis by targeted transgenic GTP-cyclohydrolase I overexpression reduces endothelial dysfunction and atherosclerosis in ApoE-knockout mice
NJ Alp et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2004)
Detection of intracellular superoxide formation in endothelial cells and intact tissues using dihydroethidium and an HPLC-based assay
B Fink et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2004)
Functional comparison of the endothelial nitric oxide synthase Glu298 Asp polymorphic variants in human endothelial cells
DM McDonald et al.
PHARMACOGENETICS (2004)
Tetrahydrobiopterin - Regulator of endothelial nitric oxide synthase in vascular disease
KM Channon
TRENDS IN CARDIOVASCULAR MEDICINE (2004)
Gene transfer of human guanosine 5′-triphosphate cyclohydrolase I restores vascular tetrahydrobiopterin level and endothelial function in low renin hypertension
JS Zheng et al.
CIRCULATION (2003)
Tetrahydrobiopterin-dependent preservation of nitric oxide-mediated endothelial function in diabetes by targeted transgenic GTP-cyclohydrolase I overexpression
NJ Alp et al.
JOURNAL OF CLINICAL INVESTIGATION (2003)
Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension
U Landmesser et al.
JOURNAL OF CLINICAL INVESTIGATION (2003)
GTP cyclohydrolase I gene transfer augments intracellular tetrahydrobiopterin in human endothelial cells: effects on nitric oxide synthase activity, protein levels and dimerisation
S Cai et al.
CARDIOVASCULAR RESEARCH (2002)
Overexpression of endothelial nitric oxide synthase accelerates atherosclerotic lesion formation in apoE-deficient mice
M Ozaki et al.
JOURNAL OF CLINICAL INVESTIGATION (2002)
Mechanisms of increased vascular superoxide production in human diabetes mellitus Role of NAD(P)H oxidase and endothelial nitric oxide synthase
TJ Guzik et al.
CIRCULATION (2002)
Tetrahydrobiopterin enhances forearm vascular response to acetylcholine in both normotensive and hypertensive individuals
Y Higashi et al.
AMERICAN JOURNAL OF HYPERTENSION (2002)
Oxidation of the zinc-thiolate complex and uncoupling of endothelial nitric oxide synthase by peroxynitrite
MH Zou et al.
JOURNAL OF CLINICAL INVESTIGATION (2002)
Tetrahydrobiopterin restores endothelial function of coronary arteries in patients with hypercholesterolaemia
Y Fukuda et al.
HEART (2002)
Structures of tetrahydrobiopterin binding-site mutants of inducible nitric oxide synthase oxygenase dimer and implicated roles of Trp457
M Aoyagi et al.
BIOCHEMISTRY (2001)
A conserved tryptophan in nitric oxide synthase regulates heme-dioxy reduction by tetrahydrobiopterin
ZQ Wang et al.
BIOCHEMISTRY (2001)
Oxygen reduction by nitric-oxide synthases
D Stuehr et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Tetrahydrobiopterin improves endothelium-dependent vasodilation by increasing nitric oxide activity in patients with Type II diabetes mellitus
T Heitzer et al.
DIABETOLOGIA (2000)
Generation of superoxide from nitric oxide synthase
J Vásquez-Vivar et al.
FEBS LETTERS (2000)
Aromatic residues and neighboring Arg414 in the (6R)-5,6,7,8-tetrahydro-L-biopterin binding site of full-length neuronal nitric-oxide synthase are crucial in catalysis and heme reduction with NADPH
I Sagami et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Tetrahydrobiopterin improves endothelium-dependent vasodilation in chronic smokers -: Evidence for a dysfunctional nitric oxide synthase
T Heitzer et al.
CIRCULATION RESEARCH (2000)
Tetrahydrobiopterin improves endothelial function in patients with coronary artery disease
W Maier et al.
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2000)