Related references
Note: Only part of the references are listed.Sost downregulation and local Wnt signaling are required for the osteogenic response to mechanical loading
Xiaolin Tu et al.
BONE (2012)
Osteocyte RANKL: New insights into the control of bone remodeling
Jinhu Xiong et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2012)
Receptor Tyrosine Kinases Activate Canonical WNT/β-Catenin Signaling via MAP Kinase/LRP6 Pathway and Direct β-Catenin Phosphorylation
Pavel Krejci et al.
PLOS ONE (2012)
The Amazing Osteocyte
Lynda F. Bonewald
JOURNAL OF BONE AND MINERAL RESEARCH (2011)
Activation of β-catenin signaling in MLO-Y4 osteocytic cells versus 2T3 osteoblastic cells by fluid flow shear stress and PGE2: Implications for the study of mechanosensation in bone
Mohamed A. Kamel et al.
BONE (2010)
Caveolin-1 regulates dorsoventral patterning through direct interaction with β-catenin in zebrafish
Saijun Mo et al.
DEVELOPMENTAL BIOLOGY (2010)
Mechano-transduction in Osteoblastic Cells Involves Strain-regulated Estrogen Receptor α-mediated Control of Insulin-like Growth Factor (IGF) I Receptor Sensitivity to Ambient IGF, Leading to Phosphatidylinositol 3-Kinase/AKT-dependent Wnt/LRP5 Receptor-independent Activation of β-Catenin Signaling
Andrew Sunters et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Mechanical Induction of PGE2 in Osteocytes Blocks Glucocorticoid-Induced Apoptosis Through Both the β-Catenin and PKA Pathways
Yukiko Kitase et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2010)
Sclerostin: A Gem From the Genome Leads to Bone-Building Antibodies
Chris Paszty et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2010)
Osteocyte Wnt/β-Catenin Signaling Is Required for Normal Bone Homeostasis
Ina Kramer et al.
MOLECULAR AND CELLULAR BIOLOGY (2010)
Phosphatidylinositol 3-Kinase Signaling Does Not Activate the Wnt Cascade
Ser Sue Ng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Mechanobiology of the Skeleton
Charles H. Turner et al.
SCIENCE SIGNALING (2009)
β-Catenin Levels Influence Rapid Mechanical Responses in Osteoblasts
Natasha Case et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Mechanical stimulation of bone in vivo reduces osteocyte expression of Sost/sclerostin
Alexander G. Robling et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
A novel ligand-independent function of the estrogen receptor is essential for osteocyte and osteoblast mechanotransduction
J. Ignacio Aguirre et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Glucocorticoids induce osteocyte apoptosis by blocking focal adhesion kinase-mediated survival - Evidence for inside-out signaling leading to anoikis
Lillian I. Plotkin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Wnt/β-catenin signaling is a component of osteoblastic bone cell early responses to load-bearing and requires estrogen receptor α
Victoria J. Armstrong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Skeletal unloading induces osteoblast apoptosis and targets α5β1-PI3K-Bcl-2 signaling in rat bone
C. Dufour et al.
EXPERIMENTAL CELL RESEARCH (2007)
Establishment of an Osteocyte-like Cell Line, MLO-Y4
Yoichi Kato et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2006)
Wnt/β-catenin signaling is a normal physiological response to mechanical loading in bone
John A. Robinson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
The Wnt co-receptor LRP5 is essential for skeletal mechanotransduction but not for the anabolic bone response to parathyroid hormone treatment
Kimihiko Sawakami et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Osteocyte apoptosis is induced by weightlessness in mice and precedes osteoclast recruitment and bone loss
JI Aguirre et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2006)
Wnt proteins prevent apoptosis of both uncommitted osteoblast progenitors and differentiated osteoblasts by β-catenin-dependent and -independent signaling cascades involving Src/ERK and phosphatidylinositol 3-kinase/AKT
M Almeida et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
The Wnt antagonist secreted frizzled-related protein-1 controls osteoblast and osteocyte apoptosis
PVN Bodine et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2005)
Mechanical stimulation prevents osteocyte apoptosis: requirement of integrins, Src kinases, and ERKs
LI Plotkin et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2005)
Genomic deletion of a long-range bone enhancer misregulates sclerostin in Van Buchem disease
GG Loots et al.
GENOME RESEARCH (2005)
Bisphosphonates and estrogens inhibit osteocyte apoptosis via distinct molecular mechanisms downstream of extracellular signal-regulated kinase activation
LI Plotkin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
LDL receptor-related proteins 5 and 6 in Wnt/β-catenin signaling:: Arrows point the way
X He et al.
DEVELOPMENT (2004)
The Wnt antagonist secreted frizzled-related protein-1 is a negative regulator of trabecular bone formation in adult mice
PVN Bodine et al.
MOLECULAR ENDOCRINOLOGY (2004)
High bone mass in mice expressing a mutant LRP5 gene
P Babij et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2003)
Wnt proteins are lipid-modified and can act as stem cell growth factors
K Willert et al.
NATURE (2003)
Mechanical loading: biphasic osteocyte survival and targeting of osteoclasts for bone destruction in rat cortical bone
BS Noble et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2003)
Transduction of cell survival signals by connexin-43 hemichannels
LI Plotkin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway
JH Mao et al.
MOLECULAR CELL (2001)
Increased bone density in sclerosteosis is due to the deficiency of a novel secreted protein (SOST)
W Balemans et al.
HUMAN MOLECULAR GENETICS (2001)
Activation and targeting of extracellular signal-regulated kinases by β-arrestin scaffolds
LM Luttrell et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Complex formation of adenomatous polyposis coli gene product and Axin facilitates glycogen synthase kinase-3β-dependent phosphorylation of β-catenin and down-regulates β-catenin
T Hinoi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
LDL-receptor-related proteins in Wnt signal transduction
K Tamai et al.
NATURE (2000)
Caveolin-1 expression inhibits Wnt/β-catenin/Lef-1 signaling by recruiting β-catenin to caveolae membrane domains
F Galbiati et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)