4.6 Article

Neutralizing Nanobodies Targeting Diverse Chemokines Effectively Inhibit Chemokine Function

Related references

Note: Only part of the references are listed.
Article Chemistry, Multidisciplinary

Targeting SDF-1/CXCL12 with a Ligand That Prevents Activation of CXCR4 through Structure-Based Drug Design

Christopher T. Veldkamp et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)

Article Multidisciplinary Sciences

CXCR4 nanobodies (VHH-based single variable domains) potently inhibit chemotaxis and HIV-1 replication and mobilize stem cells

Sven Jahnichen et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Review Pharmacology & Pharmacy

Single-domain antibodies as building blocks for novel therapeutics

Dirk Saerens et al.

CURRENT OPINION IN PHARMACOLOGY (2008)

Article Biochemistry & Molecular Biology

Small neutralizing molecules to inhibit actions of the chemokine CXCL12

Muriel Hachet-Haas et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Immunology

Ticks produce highly selective chemokine binding proteins with antiinflammatory activity

Maud Deruaz et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2008)

Article Pharmacology & Pharmacy

Noncompetitive antagonism and inverse agonism as mechanism of action of nonpeptidergic antagonists at primate and rodent CXCR3 chemokine receptors

Dennis Verzijl et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2008)

Review Biotechnology & Applied Microbiology

Properties, production, and applications of camelid single-domain antibody fragments

M. M. Harmsen et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2007)

Article Biochemistry & Molecular Biology

Molecular cloning and characterization of a highly selective chemokine-binding protein from the tick Rhipicephalus sanguineus

Achim Frauenschuh et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Medicine, General & Internal

HIV entry inhibitors

Jose A. Este et al.

LANCET (2007)

Article Oncology

Efficient inhibition of EGFR signalling and of tumour growth by antagonistic anti-EGFR Nanobodies

Rob C. Roovers et al.

CANCER IMMUNOLOGY IMMUNOTHERAPY (2007)

Review Oncology

CCL2 (Monocyte Chemoattractant Protein-1) in cancer bone metastases

Matt J. Craig et al.

CANCER AND METASTASIS REVIEWS (2006)

Article Biochemistry & Molecular Biology

Reliable and controllable antibody fragment selections from Camelid non-immune libraries for target validation

Peter Verheesen et al.

BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2006)

Article Biochemistry & Molecular Biology

The biological relevance of chemokine-proteoglycan interactions

A. E. I. Proudfoot

BIOCHEMICAL SOCIETY TRANSACTIONS (2006)

Article Multidisciplinary Sciences

Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies

E De Genst et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Biochemistry & Molecular Biology

The chemokine SDF-1/CXCL12 binds to and signals through the orphan receptor RDC1 in T lymphocytes

K Balabanian et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Biochemistry & Molecular Biology

Induced refolding of a temperature denatured llama heavy-chain antibody fragment by its antigen

E Dolk et al.

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2005)

Review Immunology

Post-translational control of chemokines: a role for,decoy receptors?

L Comerford et al.

IMMUNOLOGY LETTERS (2005)

Article Biotechnology & Applied Microbiology

Isolation of llama antibody fragments for prevention of dandruff by phage display in shampoo

E Dolk et al.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2005)

Article Oncology

Pivotal role of CXCR3 in melanoma cell metastasis to lymph nodes

K Kawada et al.

CANCER RESEARCH (2004)

Review Cardiac & Cardiovascular Systems

Chemokines in the pathogenesis of vascular disease

IF Charo et al.

CIRCULATION RESEARCH (2004)

Review Immunology

Viral mimicry of cytokines, chemokines and their receptors

A Alcami

NATURE REVIEWS IMMUNOLOGY (2003)

Article Biochemistry & Molecular Biology

Single-domain antibody fragments with high conformational stability

M Dumoulin et al.

PROTEIN SCIENCE (2002)

Review Pharmacology & Pharmacy

Target validation of G-protein coupled receptors

A Wise et al.

DRUG DISCOVERY TODAY (2002)

Article Multidisciplinary Sciences

Involvement of chemokine receptors in breast cancer metastasis

A Müller et al.

NATURE (2001)

Article Pathology

Role of Rantes in experimental cardiac allograft rejection

MS Mulligan et al.

EXPERIMENTAL AND MOLECULAR PATHOLOGY (2000)

Article Immunology

Requirement of the chemokine receptor CXCR3 for acute allograft rejection

WW Hancock et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2000)