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Ca2+-dependent Transcriptional Control of Ca2+ Homeostasis

Journal

JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 287, Issue 38, Pages 31674-31680

Publisher

AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC
DOI: 10.1074/jbc.R112.384982

Keywords

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Funding

  1. Direccion General de Investigacion Cientifica y Tecnica (DGICYT) [SAF2008-03469, SAF2010-21784]
  2. CIBERNED
  3. Fundacion Reina Sofia Grant [PI 006/09]
  4. European Union 6th Framework Program (NeuroNE) [LSHG-CT-2006-037627]

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Intracellular free Ca2+ ions regulate many cellular functions, and in turn, the cell devotes many genes/proteins to keep tight control of the level of intracellular free Ca2+. Here, we review recent work on Ca2+- dependent mechanisms and effectors that regulate the transcription of genes encoding proteins involved in the maintenance of the homeostasis of Ca2+ in the cell.

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