4.6 Article

Identification of Luminal Loop 1 of Scap Protein as the Sterol Sensor That Maintains Cholesterol Homeostasis

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Purified NPC1 protein - I. Binding of cholesterol and oxysterols to a 1278-amino acid membrane protein

Rodney E. Infante et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Multidisciplinary Sciences

Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: Oxysterols block transport by binding to Insig

Arun Radhakrishnan et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Multidisciplinary Sciences

Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: Insig renders sorting signal in Scap inaccessible to COPII proteins

Li-Ping Sun et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Review Biochemistry & Molecular Biology

Protein sensors for membrane sterols

JL Goldstein et al.

Article Biochemistry & Molecular Biology

Insig required for sterol-mediated inhibition of Scap/SREBP binding to COPII proteins in vitro

LP Sun et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Multidisciplinary Sciences

Intramembrane aspartic acid in SCAP protein governs cholesterol-induced conformational change

JD Feramisco et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Article Biochemistry & Molecular Biology

Direct binding of cholesterol to the purified membrane region of SCAP: Mechanism for a sterol-sensing domain

A Radhakrishnan et al.

MOLECULAR CELL (2004)

Article Multidisciplinary Sciences

Three mutations in sterol-sensing domain of SCAP block interaction with insig and render SREBP cleavage insensitive to sterols

D Yabe et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

Article Multidisciplinary Sciences

Insig-2, a second endoplasmic reticulum protein that binds SCAP and blocks export of sterol regulatory element-binding proteins

D Yabe et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

Article Biochemistry & Molecular Biology

The P1′ specificity of tobacco etch virus protease

RB Kapust et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)

Review Medicine, Research & Experimental

SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

JD Horton et al.

JOURNAL OF CLINICAL INVESTIGATION (2002)

Article Biochemistry & Molecular Biology

Unsaturated fatty acids down-regulate SREBP isoforms 1a and 1c by two mechanisms in HEK-293 cells

VC Hannah et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2001)

Article Biochemistry & Molecular Biology

Regulated step in cholesterol feedback localized to budding of SCAP from ER membranes

A Nohturfft et al.