Related references
Note: Only part of the references are listed.High Expression of Sphingosine 1-Phosphate Receptors, S1P1 and S1P3, Sphingosine Kinase 1, and Extracellular Signal-Regulated Kinase-1/2 Is Associated with Development of Tamoxifen Resistance in Estrogen Receptor-Positive Breast Cancer Patients
Carol Watson et al.
AMERICAN JOURNAL OF PATHOLOGY (2010)
FTY720 and (S)-FTY720 vinylphosphonate inhibit sphingosine kinase 1 and promote its proteasomal degradation in human pulmonary artery smooth muscle, breast cancer and androgen-independent prostate cancer cells
Francesca Tonelli et al.
CELLULAR SIGNALLING (2010)
The Sphingosine Kinase 1 Inhibitor 2-(p-Hydroxyanilino)-4-(p-chlorophenyl)thiazole Induces Proteasomal Degradation of Sphingosine Kinase 1 in Mammalian Cells
Carolyn Loveridge et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Sphingosine Kinase 1 Induces Tolerance to Human Epidermal Growth Factor Receptor 2 and Prevents Formation of a Migratory Phenotype in Response to Sphingosine 1-Phosphate in Estrogen Receptor-Positive Breast Cancer Cells
Jaclyn S. Long et al.
MOLECULAR AND CELLULAR BIOLOGY (2010)
Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2
Sergio E. Alvarez et al.
NATURE (2010)
Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis
Volker Brinkmann et al.
NATURE REVIEWS DRUG DISCOVERY (2010)
Sphingosine 1-phosphate and cancer
Nigel J. Pyne et al.
NATURE REVIEWS CANCER (2010)
Regulation of Histone Acetylation in the Nucleus by Sphingosine-1-Phosphate
Nitai C. Hait et al.
SCIENCE (2009)
Suppression of ulcerative colitis in mice by orally available inhibitors of sphingosine kinase
Lynn W. Maines et al.
DIGESTIVE DISEASES AND SCIENCES (2008)
Antitumor activity of sphingosine kinase inhibitors
Kevin J. French et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2006)
Validation of an anti-sphingosine-1-phosphate antibody as a potential therapeutic in reducing growth, invasion, and angiogenesis in multiple tumor lineages
B Visentin et al.
CANCER CELL (2006)
Mouse sphingosine kinase isoforms SPHK1a and SPHK1b differ in enzymatic traits including stability, localization, modification, and oligomerization
A Kihara et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Sphingosine kinase 1 is up-regulated in colon carcinogenesis
Toshihiko Kawamori et al.
FASEB JOURNAL (2006)
FTY720, a fungus metabolite, inhibits in vivo growth of androgen-independent prostate cancer
CW Chua et al.
INTERNATIONAL JOURNAL OF CANCER (2005)
Loss of sphingosine kinase-1 activates the intrinsic pathway of programmed cell death: modulation of sphingolipid levels and the induction of apoptosis
TA Taha et al.
FASEB JOURNAL (2005)
Effects of a novel immunomodulating agent, FTY720, on tumor growth and angiogenesis in hepatocellular carcinoma
JWY Ho et al.
MOLECULAR CANCER THERAPEUTICS (2005)
Asp177 in C4 domain of mouse sphingosine kinase 1a is important for the sphingosine recognition
S Yokota et al.
FEBS LETTERS (2004)
The immunosuppressant FTY720 down-regulates sphingosine 1-phosphate G protein-coupled receptors
MH Graler et al.
FASEB JOURNAL (2004)
Sphingosine kinase 1 is an intracellular effector of phosphatidic acid
C Delon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Phosphorylation and action of the immunomodulator FTY720 inhibits vascular endothelial cell growth factor-induced vascular permeability
T Sanchez et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Induction of apoptosis in human bladder cancer cells in vitro and in vivo caused by FTY720 treatment
H Azuma et al.
JOURNAL OF UROLOGY (2003)
The immune modulator FTY720 targets sphingosine 1-phosphate receptors
V Brinkmann et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists
S Mandala et al.
SCIENCE (2002)
Tethering of the platelet-derived growth factor ß receptor to G-protein-coupled receptors -: A novel platform for integrative signaling by these receptor classes in mammalian cells
F Alderton et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Relationships between inhibition constants, inhibitor concentrations for 50% inhibition and types of inhibition:: new ways of analysing data
A Cortés et al.
BIOCHEMICAL JOURNAL (2001)
Expression of a catalytically inactive sphingosine kinase mutant blocks agonist-induced sphingosine kinase activation - A dominant-negative sphingosine kinase
SM Pitson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)