Related references
Note: Only part of the references are listed.Local cholesterol increase triggers amyloid precursor protein-Bace1 clustering in lipid rafts and rapid endocytosis
Catherine Marquer et al.
FASEB JOURNAL (2011)
Efficacy of a medical food in mild Alzheimer's disease: A randomized, controlled trial
Philip Scheltens et al.
ALZHEIMERS & DEMENTIA (2010)
Can Nutrients Prevent or Delay Onset of Alzheimer's Disease?
Patrick J. G. H. Kamphuis et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
Long Chain-Polyunsaturated Fatty Adds Modulate Membrane Phospholipid Composition and Protein Localization in Lipid Rafts of Neural Stem Cell Cultures
Benedicte Langelier et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2010)
Lipid-Lowering Treatment Is Related to Decreased Risk of Dementia: A Population-Based Study (FINRISK)
A. Solomon et al.
NEURODEGENERATIVE DISEASES (2010)
Randomized controlled trial of atorvastatin in mild to moderate Alzheimer disease LEADe
H. H. Feldman et al.
NEUROLOGY (2010)
Diet-induced docosahexaenoic acid non-raft domains and lymphocyte function
Saame Raza Shaikh
PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS (2010)
Dietary fish and meat intake and dementia in Latin America, China, and India: a 10/66 Dementia Research Group population-based study
Emiliano Albanese et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2009)
Oleic- and docosahexaenoic acid-containing phosphatidylethanolamines differentially phase separate from sphingomyelin
Saame Raza Shaikh et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2009)
Cell biology, regulation and inhibition of β-secretase (BACE-1)
Clare E. Hunt et al.
FEBS JOURNAL (2009)
S-Palmitoylation of γ-Secretase Subunits Nicastrin and APH-1
Haipeng Cheng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Alzheimer Disease Aβ Production in the Absence of S-Palmitoylation-dependent Targeting of BACE1 to Lipid Rafts
Kulandaivelu S. Vetrivel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
A novel reciprocal and biphasic relationship between membrane cholesterol and beta-secretase activity in SH-SY5Y cells and in human platelets
Wei Wei Liu et al.
JOURNAL OF NEUROCHEMISTRY (2009)
Mild cholesterol depletion reduces amyloid-β production by impairing APP trafficking to the cell surface
C. Guardia-Laguarta et al.
JOURNAL OF NEUROCHEMISTRY (2009)
Docosahexaenoic Acid Modifies the Clustering and Size of Lipid Rafts and the Lateral Organization and Surface Expression of MHC Class I of EL4 Cells
Saame Raza Shaikh et al.
JOURNAL OF NUTRITION (2009)
Toxicology and safety of DHA
Eric L. Lien
PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS (2009)
Omega-3 fatty acids and dementia
Greg M. Cole et al.
PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS (2009)
Active γ-secretase is localized to detergent-resistant membranes in human brain
Ji-Yeun Hur et al.
FEBS JOURNAL (2008)
Independent inhibition of Alzheimer disease β- and γ-secretase cleavage by lowered cholesterol levels
Marcus O. W. Grimm et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Membrane microdomain switching: a regulatory mechanism of amyloid precursor protein processing
Takashi Sakurai et al.
JOURNAL OF CELL BIOLOGY (2008)
Effect of fish oil on cognitive performance in older subjects - A randomized, controlled trial
O. van de Rest et al.
NEUROLOGY (2008)
Presenilins:: Members of the γ-secretase quartets, but part-time soloists too
Tomoko Wakabayashi et al.
PHYSIOLOGY (2008)
The effects of omega-3 fatty acids monotherapy in Alzheimer's disease and mild cognitive impairment: A preliminary randomized double-blind placebo-controlled study
Chih-Chiang Chiu et al.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2008)
Brain metabolism of nutritionally essential polyunsaturated fatty acids depends on both the diet and the liver
Stanley I. Rapoport et al.
PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS (2007)
Changes in cerebral blood volume and amyloid pathology in aged Alzheimer APP/PS1 mice on a docosahexaenoic acid (DHA) diet or cholesterol enriched Typical Western Diet (TWD)
C. R. Hooijmans et al.
NEUROBIOLOGY OF DISEASE (2007)
Dietary docosahexaenoic acid and docosapentaenoic acid ameliorate amyloid-β and tau pathology via a mechanism involving presenilin 1 levels
Kim N. Green et al.
JOURNAL OF NEUROSCIENCE (2007)
Plasma phosphatidylcholine docosahexaenoic acid content and risk of dementia and Alzheimer disease - The Framingham heart study
Ernst J. Schaefer et al.
ARCHIVES OF NEUROLOGY (2006)
Dietary supplementation of arachidonic and docosahexaenoic acids improves cognitive dysfunction
Susumu Kotani et al.
NEUROSCIENCE RESEARCH (2006)
ω-3 fatty acid treatment in 174 patients with mild to moderate Alzheimer disease:: OmegAD study -: A randomized double-blind trial
Yvonne Freund-Levi et al.
ARCHIVES OF NEUROLOGY (2006)
Impact of different saturated fatty acid, polyunsaturated fatty acid and cholesterol containing diets on beta-amyloid accumulation in APP/PS1 transgenic mice
M. Oksman et al.
NEUROBIOLOGY OF DISEASE (2006)
Cholesterol depletion reduces aggregation of amyloid-beta peptide in hippocampal neurons
Anja Schneider et al.
NEUROBIOLOGY OF DISEASE (2006)
Regulation of cholesterol and sphingomyelin metabolism by amyloid-β and presenilin
MOW Grimm et al.
NATURE CELL BIOLOGY (2005)
A role for docosahexaenoic acid-derived neuroprotectin D1 in neural cell survival and Alzheimer disease
WJ Lukiw et al.
JOURNAL OF CLINICAL INVESTIGATION (2005)
Atorvastatin for the treatment of mild to moderate Alzheimer disease - Preliminary results
DL Sparks et al.
ARCHIVES OF NEUROLOGY (2005)
Docosahexaenoic acid in the diet: its importance in maintenance and restoration of neural membrane function
LA Horrocks et al.
PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS (2004)
Docosahexaenoic acid protects from dendritic pathology in an Alzheimer's disease mouse model
F Calon et al.
NEURON (2004)
Neuronal membrane cholesterol loss enhances amyloid pepticle generation
J Abad-Rodriguez et al.
JOURNAL OF CELL BIOLOGY (2004)
PKD1/PKCμ promotes αvβ3 integrin recycling and delivery to nascent focal adhesions
AJ Woods et al.
EMBO JOURNAL (2004)
The role of ADAM10 and ADAM17 in the ectodomain shedding of angiotensin converting enzyme and the amyloid precursor protein
TMJ Allinson et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2004)
Exclusively targeting β-secretase to lipid rafts by GPI-anchor addition up-regulates β-site processing of the amyloid precursor protein
JM Cordy et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Regulated hyperaccumulation of presenilin-1 and the γ-secretase complex -: Evidence for differential intramembranous processing of transmembrane substrates
SH Kim et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Mild hypercholesterolemia is an early risk factor for the development of Alzheimer amyloid pathology
MA Pappolla et al.
NEUROLOGY (2003)
Consumption of fish and n-3 fatty acids and risk of incident Alzheimer disease
MC Morris et al.
ARCHIVES OF NEUROLOGY (2003)
γ-secretase is a membrane protein complex comprised of presenilin, nicastrin, aph-1, and pen-2
WT Kimberly et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Low serum cholesteryl ester-docosahexaenoic acid levels in Alzheimer's disease: a case-control study
AM Tully et al.
BRITISH JOURNAL OF NUTRITION (2003)
The role of presenilin cofactors in the γ-secretase complex
N Takasugi et al.
NATURE (2003)
Amyloidogenic processing of the Alzheimer β-amyloid precursor protein depends on lipid rafts
R Ehehalt et al.
JOURNAL OF CELL BIOLOGY (2003)
Fish, meat, and risk of dementia:: cohort study
P Barberger-Gateau et al.
BRITISH MEDICAL JOURNAL (2002)
Treatment with simvastatin in normocholesterolemic patients with Alzheimer's disease:: A 26-week randomized, placebo-controlled, double-blind trial
M Simons et al.
ANNALS OF NEUROLOGY (2002)
Lipid rafts play an important role in Aβ biogenesis by regulating the β-secretase pathway
H Tun et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2002)
γ-Secretase, notch, Aβ and Alzheimer's disease:: Where do the presenilins fit in?
SS Sisodia et al.
NATURE REVIEWS NEUROSCIENCE (2002)
Diet-induced hypercholesterolemia enhances brain Aβ accumulation in transgenic mice
FS Shie et al.
NEUROREPORT (2002)
Cholesterol-dependent γ-secretase activity in buoyant cholesterol-rich membrane microdomains
S Wahrle et al.
NEUROBIOLOGY OF DISEASE (2002)
Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method
KJ Livak et al.
METHODS (2001)
Simvastatin strongly reduces levels of Alzheimer's disease β-amyloid peptides Aβ42 and Aβ40 in vitro and in vivo
K Fassbender et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Maturation and endosomal targeting of β-site amyloid precursor protein-cleaving enzyme -: The Alzheimer's disease β-secretase
JT Huse et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)