Related references
Note: Only part of the references are listed.Liver Steatosis and Increased ChREBP Expression in Mice Carrying a Liver Specific SIRT1 Null Mutation under a Normal Feeding Condition
Rui-Hong Wang et al.
International Journal of Biological Sciences (2012)
Fatty liver is associated with reduced SIRT3 activity and mitochondrial protein hyperacetylation
Agnieszka A. Kendrick et al.
BIOCHEMICAL JOURNAL (2011)
Sirt3 Promotes the Urea Cycle and Fatty Acid Oxidation during Dietary Restriction
William C. Hallows et al.
MOLECULAR CELL (2011)
Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophy
Angela V. Hafner et al.
AGING-US (2010)
Involvement of adiponectin-SIRT1-AMPK signaling in the protective action of rosiglitazone against alcoholic fatty liver in mice
Zheng Shen et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2010)
Nicotinamide phosphoribosyltransferase (NAMPT/PBEF/visfatin) is constitutively released from human hepatocytes
A. Garten et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
Regulation of Succinate Dehydrogenase Activity by SIRT3 in Mammalian Mitochondria
Huseyin Cimen et al.
BIOCHEMISTRY (2010)
SIRT3 Deacetylates Mitochondrial 3-Hydroxy-3-Methylglutaryl CoA Synthase 2 and Regulates Ketone Body Production
Tadahiro Shimazu et al.
CELL METABOLISM (2010)
Hepatic-Specific Disruption of SIRT6 in Mice Results in Fatty Liver Formation Due to Enhanced Glycolysis and Triglyceride Synthesis
Hyun-Seok Kim et al.
CELL METABOLISM (2010)
Pre-B Cell Colony Enhancing Factor/NAMPT/Visfatin in Inflammation and Obesity- Related Disorders
Alexander R. Moschen et al.
CURRENT PHARMACEUTICAL DESIGN (2010)
Lack of SIRT1 (Mammalian Sirtuin 1) Activity Leads to Liver Steatosis in the SIRT1(+/-) Mice: A Role of Lipid Mobilization and Inflammation
Fen Xu et al.
ENDOCRINOLOGY (2010)
FoxO1 Links Hepatic Insulin Action to Endoplasmic Reticulum Stress
Adama Kamagate et al.
ENDOCRINOLOGY (2010)
SIRT3 is regulated by nutrient excess and modulates hepatic susceptibility to lipotoxicity
Jianjun Bao et al.
FREE RADICAL BIOLOGY AND MEDICINE (2010)
Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP
Amy K. Walker et al.
GENES & DEVELOPMENT (2010)
Abnormal expressions of circadian-clock and circadian clock-controlled genes in the livers and kidneys of long-term, high-fat-diet-treated mice
M-C Hsieh et al.
INTERNATIONAL JOURNAL OF OBESITY (2010)
Hepatic FoxO1 Ablation Exacerbates Lipid Abnormalities during Hyperglycemia
Rebecca A. Haeusler et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
SIRT1 Deacetylates and Inhibits SREBP-1C Activity in Regulation of Hepatic Lipid Metabolism
Bhaskar Ponugoti et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
SIRT4 Regulates Fatty Acid Oxidation and Mitochondrial Gene Expression in Liver and Muscle Cells
Nargis Nasrin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Intracellular Nicotinamide Phosphoribosyltransferase Protects against Hepatocyte Apoptosis and Is Down-Regulated in Nonalcoholic Fatty Liver Disease
Tuva B. Dahl et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2010)
MAPK phosphatase-3 promotes hepatic gluconeogenesis through dephosphorylation of forkhead box O1 in mice
Zhidan Wu et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
SIRT3 reduces lipid accumulation via AMPK activation in human hepatic cells
Tong Shi et al.
JOURNAL OF DIGESTIVE DISEASES (2010)
The Developmental Origins, Mechanisms, and Implications of Metabolic Syndrome
Kimberley D. Bruce et al.
JOURNAL OF NUTRITION (2010)
SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation
Matthew D. Hirschey et al.
NATURE (2010)
Sirtuin 3, a New Target of PGC-1α, Plays an Important Role in the Suppression of ROS and Mitochondrial Biogenesis
Xingxing Kong et al.
PLOS ONE (2010)
Circadian Integration of Metabolism and Energetics
Joseph Bass et al.
SCIENCE (2010)
Sirtuin regulation of mitochondria: energy production, apoptosis, and signaling
Eric Verdin et al.
TRENDS IN BIOCHEMICAL SCIENCES (2010)
Diet and exercise signals regulate SIRT3 and activate AMPK and PGC-1α in skeletal muscle
Orsolya M. Palacios et al.
AGING-US (2009)
Akt2 Is Required for Hepatic Lipid Accumulation in Models of Insulin Resistance
Karla F. Leavens et al.
CELL METABOLISM (2009)
Hepatocyte-Specific Deletion of SIRT1 Alters Fatty Acid Metabolism and Results in Hepatic Steatosis and Inflammation
Aparna Purushotham et al.
CELL METABOLISM (2009)
FoxO1 Haploinsufficiency Protects Against High-Fat Diet-Induced Insulin Resistance With Enhanced Peroxisome Proliferator-Activated Receptor γ Activation in Adipose Tissue
Jane J. Kim et al.
DIABETES (2009)
Therapeutic potential of SIRT1 and NAMPT-mediated NAD biosynthesis in type 2 diabetes
Shin-ichiro Imai et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2009)
SIRT2 Suppresses Adipocyte Differentiation by Deacetylating FOXO1 and Enhancing FOXO1's Repressive Interaction with PPARγ
Fei Wang et al.
MOLECULAR BIOLOGY OF THE CELL (2009)
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
Carles Canto et al.
NATURE (2009)
Foxo1 integrates insulin signaling with mitochondrial function in the liver
Zhiyong Cheng et al.
NATURE MEDICINE (2009)
Intracellular NAD levels regulate tumor necrosis factor protein synthesis in a sirtuin-dependent manner
Frederic Van Gool et al.
NATURE MEDICINE (2009)
Circadian Control of the NAD+ Salvage Pathway by CLOCK-SIRT1
Yasukazu Nakahata et al.
SCIENCE (2009)
Circadian Clock Feedback Cycle Through NAMPT-Mediated NAD(+) Biosynthesis
Kathryn Moynihan Ramsey et al.
SCIENCE (2009)
Nampt: linking NAD biology, metabolism and cancer
Antje Garten et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2009)
Nicotinic acid nicotinamide and nicotinamide riboside: A molecular evaluation of NAD(+) precursor vitamins in human nutrition
Katrina L. Bogan et al.
ANNUAL REVIEW OF NUTRITION (2008)
Inactivation of hepatic Foxo1 by insulin signaling is required for adaptive nutrient homeostasis and endocrine growth regulation
Xiaocheng C. Dong et al.
CELL METABOLISM (2008)
Hepatic insulin resistance is sufficient to produce dyslipidemia and susceptibility to atherosclerosis
Sudha B. Biddinger et al.
CELL METABOLISM (2008)
Specific SIRT1 Activation Mimics Low Energy Levels and Protects against Diet-induced Metabolic Disorders by Enhancing Fat Oxidation
Jerome N. Feige et al.
CELL METABOLISM (2008)
SIRT1 regulates hepatocyte lipid metabolism through activating AMP-activated protein kinase
Xiuyun Hou et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Nicotinamide phosphoribosyl transferase/pre-B cell colony-enhancing factor/visfatin is required for lymphocyte development and cellular resistance to genotoxic stress
Anthony Rongvaux et al.
JOURNAL OF IMMUNOLOGY (2008)
Substrates and regulation mechanisms for the human mitochondrial Sirtuins Sirt3 and Sirt5
Christine Schlicker et al.
JOURNAL OF MOLECULAR BIOLOGY (2008)
A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange
Yi Liu et al.
NATURE (2008)
The role of FoxO in the regulation of metabolism
D. N. Gross et al.
ONCOGENE (2008)
FOXO animal models reveal a variety of diverse roles for FOXO transcription factors
K. C. Arden
ONCOGENE (2008)
A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis
Bong-Hyun Ahn et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Sirt1 protects against high-fat diet-induced metabolic damage
Paul T. Pfluger et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Mammalian sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation
David B. Lombard et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Nampt/PBEF/Visfatin regulates insulin secretion in β cells as a systemic NAD biosynthetic enzyme
Javier R. Revollo et al.
CELL METABOLISM (2007)
High-fat diet disrupts behavioral and molecular circadian rhythms in mice
Akira Kohsaka et al.
CELL METABOLISM (2007)
SIRT2 regulates adipocyte differentiation through FoxO1 acetylation/deacetylation
Enxuan Jing et al.
CELL METABOLISM (2007)
Fasting-dependent glucose and lipid metabolic response through hepatic sirtuin 1
Joseph T. Rodgers et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Visfatin is released from 3T3-L1 adipocytes via a non-classical pathway
Masaki Tanaka et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Visfatin expression is hormonally regulated by metabolic and sex hormones in 3T3-L1 pre-adipocytes and adipocytes
R. MacLaren et al.
DIABETES OBESITY & METABOLISM (2007)
Hepatic de novo lipogenesis is present in liver-specific ACC1-deficient mice
Naomoto Harada et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
p38 mitogen-activated protein kinase plays an inhibitory role in hepatic lipogenesis
Yan Xiong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis
Ji-Hye Paik et al.
CELL (2007)
Impaired regulation of hepatic glucose production in mice lacking the forkhead transcription factor foxo1 in liver
Michihiro Matsumoto et al.
CELL METABOLISM (2007)
Sirtuins as potential targets for metabolic syndrome
Leonard Guarente
NATURE (2006)
Aberrant forkhead box O1 function is associated with impaired hepatic metabolism
Shen Qu et al.
ENDOCRINOLOGY (2006)
Dual role of transcription factor FoxO1 in controlling hepatic insulin sensitivity and lipid metabolism
Michihiro Matsumoto et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2
Bjoern Schwer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Structure of Nampt/PBEF/visfatin, a mammalian NAD+ biosynthetic enzyme
Tao Wang et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2006)
Targeting Foxo1 in mice using antisense oligonucleotide improves hepatic and peripheral insulin action
Varman T. Samuel et al.
DIABETES (2006)
Molecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents
Javed A. Khan et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2006)
APPL1 binds to adiponectin receptors and mediates adiponectin signalling and function
XM Mao et al.
NATURE CELL BIOLOGY (2006)
FoxO1 regulates multiple metabolic pathways in the liver - Effects on gluconeogenic, glycolytic, and lipogenic gene expression
WW Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Irs1 and Irs2 signaling is essential for hepatic glucose homeostasis and systemic growth
XC Dong et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
FoxO1 protects against pancreatic β cell failure through NeuroD and MafA induction
YI Kitamura et al.
CELL METABOLISM (2005)
Hormonal regulation of the novel adipocytokine visfatin in 3T3-L1 adipocytes
S Kralisch et al.
JOURNAL OF ENDOCRINOLOGY (2005)
FoxO proteins in insulin action and metabolism
A Barthel et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2005)
SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes
T Shi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Suppression of FOXO1 activity by FHL2 through SIRT1-mediated deacetylation
YH Yang et al.
EMBO JOURNAL (2005)
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
A Brunet et al.
SCIENCE (2004)
Mammalian SIRT1 represses forkhead transcription factors
MC Motta et al.
CELL (2004)
The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells
JR Revollo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Foxo1 mediates insulin action on apoC-III and triglyceride metabolism
J Altomonte et al.
JOURNAL OF CLINICAL INVESTIGATION (2004)
FoxOs at the crossroads of cellular metabolism, differentiation, and transformation
D Accili et al.
CELL (2004)
Inhibition of Foxo1 function is associated with improved fasting glycemia in diabetic mice
J Altomonte et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2003)
Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice
HL Cheng et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1α interaction
P Puigserver et al.
NATURE (2003)
Inhibitors of histone deacetylase and DNA methyltransfcrase synergistically activate the methylated metallothionein I promoter by activating the transcription factor MTF-1 and forming an open chromatin structure
K Ghoshal et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family
JS Smith et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
S Imai et al.
NATURE (2000)