4.6 Article

Insights into Radicicol Biosynthesis via Heterologous Synthesis of Intermediates and Analogs

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

A Novel Fungal Flavin-Dependent Halogenase for Natural Product Biosynthesis

Jia Zeng et al.

CHEMBIOCHEM (2010)

Article Biochemistry & Molecular Biology

Identification of the Viridicatumtoxin and Griseofulvin Gene Clusters from Penicillium aethiopicum

Yit-Heng Chooi et al.

CHEMISTRY & BIOLOGY (2010)

Article Chemistry, Multidisciplinary

Targeting the Hsp90 Chaperone: Synthesis of Novel Resorcylic Acid Macrolactone Inhibitors of Hsp90

James E. H. Day et al.

CHEMISTRY-A EUROPEAN JOURNAL (2010)

Article Multidisciplinary Sciences

Structure and function of an iterative polyketide synthase thioesterase domain catalyzing Claisen cyclization in aflatoxin biosynthesis

Tyler Paz Korman et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Multidisciplinary Sciences

A flavin-dependent halogenase catalyzes the chlorination step in the biosynthesis of Dictyostelium differentiation-inducing factor 1

Christopher S. Neumann et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Biochemistry & Molecular Biology

Crystal Structures of Dehydratase Domains from the Curacin Polyketide Biosynthetic Pathway

David L. Akey et al.

STRUCTURE (2010)

Article Chemistry, Medicinal

Synthesis of pochoxime prodrugs as potent HSP90 inhibitors

Cuihua Wang et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2009)

Article Biochemistry & Molecular Biology

Biosynthesis of Resorcylic Acid Lactone Lasiodiplodin in Lasiodiplodia theobromae

Takasumi Kashima et al.

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2009)

Article Biochemistry & Molecular Biology

Inhibition of HSP90 with Pochoximes: SAR and Structure-Based Insights

Sofia Barluenga et al.

CHEMBIOCHEM (2009)

Review Chemistry, Multidisciplinary

Chemistry and Biology of Mycotoxins and Related Fungal Metabolites

Stefan Braese et al.

CHEMICAL REVIEWS (2009)

Article Chemistry, Multidisciplinary

Acyltransferase Mediated Polyketide Release from a Fungal Megasynthase

Xinkai Xie et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)

Article Multidisciplinary Sciences

Complete Reconstitution of a Highly Reducing Iterative Polyketide Synthase

Suzanne M. Ma et al.

SCIENCE (2009)

Article Chemistry, Multidisciplinary

Divergent synthesis of a pochonin library targeting HSP90 and in vivo efficacy of an identified inhibitor

Sofia Barluenga et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2008)

Article Biotechnology & Applied Microbiology

Genes for the biosynthesis of the fungal polyketides hypothemycin from Hypomyces subiculosus and radicicol from Pochonia chlamydosporia

Christopher D. Reeves et al.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2008)

Review Biochemistry & Molecular Biology

Halogenation strategies in natural product biosynthesis

Christopher S. Neumann et al.

CHEMISTRY & BIOLOGY (2008)

Article Biochemistry & Molecular Biology

Crystal Structure of the Erythromycin Polyketide Synthase Dehydratase

Adrian Keatinge-Clay

JOURNAL OF MOLECULAR BIOLOGY (2008)

Article Chemistry, Multidisciplinary

Stereospecificity of ketoreductase domains 1 and 2 of the tylactone modular polyketide synthase

Roselyne Castonguay et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)

Article Multidisciplinary Sciences

A polyketide macrolactone synthase from the filamentous fungus Gibberella zeae

Hui Zhou et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Multidisciplinary Sciences

Deconstruction of iterative multidomain polyketide synthase function

Jason M. Crawford et al.

SCIENCE (2008)

Article Chemistry, Multidisciplinary

Stereospecificity of ketoreductase domains of the 6-deoxyerythronolide B synthase

Roselyne Castonguay et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2007)

Article Chemistry, Multidisciplinary

Enzymatic synthesis of aromatic polyketides using PKS4 from Gibberella fujikuroi

Suzanne M. Ma et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2007)

Article Biochemistry & Molecular Biology

A tylosin ketoreductase reveals how chirality is determined in polyketides

Adrian T. Keatinge-Clay

CHEMISTRY & BIOLOGY (2007)

Article Biochemistry & Molecular Biology

Chlorination by a long-lived intermediate in the mechanism of flavin-dependent halogenases

Ellen Yeh et al.

BIOCHEMISTRY (2007)

Article Chemistry, Organic

Polyketides, proteins and genes in fungi: programmed nano-machines begin to reveal their secrets

Russell J. Cox

ORGANIC & BIOMOLECULAR CHEMISTRY (2007)

Article Chemistry, Multidisciplinary

Modular synthesis of radicicol a and related resorcylic acid lactones, potent kinase inhibitors

Pierre-Yves Dakas et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2007)

Review Biochemistry & Molecular Biology

Natural products of filamentous fungi: enzymes, genes, and their regulation

Dirk Hoffmeister et al.

NATURAL PRODUCT REPORTS (2007)

Article Multidisciplinary Sciences

Identification of a starter unit acyl-carrier protein transacylase domain in an iterative type I polyketide synthase

Jason M. Crawford et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Biotechnology & Applied Microbiology

Characterization of two polyketide synthase genes involved in zearalenone biosynthesis in Gibberella zeae

I Gaffoor et al.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2006)

Article Biochemistry & Molecular Biology

Two different polyketide synthase genes are required for synthesis of zearalenone in Gibberella zeae

YT Kim et al.

MOLECULAR MICROBIOLOGY (2005)

Article Biotechnology & Applied Microbiology

Combinatorial polyketide biosynthesis by de novo design and rearrangement of modular polyketide synthase genes

HG Menzella et al.

NATURE BIOTECHNOLOGY (2005)

Article Chemistry, Multidisciplinary

Design, synthesis, and biological evaluation of HSP90 inhibitors based on conformational analysis of radicicol and its analogues

E Moulin et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)

Article Chemistry, Medicinal

Synthesis and antitumor activity of novel O-carbamoylmethyloxime derivatives of radicicol

Y Ikuina et al.

JOURNAL OF MEDICINAL CHEMISTRY (2003)

Article Oncology

Overview: Translating Hsp90 Biology into Hsp90 Drugs

Paul Workman

CURRENT CANCER DRUG TARGETS (2003)

Article Oncology

Development of Radicicol Analogues

Shiro Soga et al.

CURRENT CANCER DRUG TARGETS (2003)

Article Biochemistry & Molecular Biology

Halohydrin and oxime derivatives of radicicol: Synthesis and antitumor activities

T Agatsuma et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2002)