Related references
Note: Only part of the references are listed.Fibrillar Oligomers Nucleate the Oligomerization of Monomeric Amyloid β but Do Not Seed Fibril Formation
Jessica W. Wu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
A causative link between the structure of aberrant protein oligomers and their toxicity
Silvia Campioni et al.
NATURE CHEMICAL BIOLOGY (2010)
EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity
Jan Bieschke et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Development of Tau Aggregation Inhibitors for Alzheimer's Disease
Bruno Bulic et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2009)
Amyloid Protofibrils of Lysozyme Nucleate and Grow Via Oligomer Fusion
Shannon E. Hill et al.
BIOPHYSICAL JOURNAL (2009)
Model Discrimination and Mechanistic Interpretation of Kinetic Data in Protein Aggregation Studies
Joseph P. Bernacki et al.
BIOPHYSICAL JOURNAL (2009)
Reduced IGF-1 Signaling Delays Age-Associated Proteotoxicity in Mice
Ehud Cohen et al.
CELL (2009)
Fluorescence microscopy studies on islet amyloid polypeptide fibrillation at heterogeneous and cellular membrane interfaces and its inhibition by resveratrol
Diana Radovan et al.
FEBS LETTERS (2009)
The Quest for Small Molecules as Amyloid Inhibiting Therapies for Alzheimer's Disease
Hozefa Amijee et al.
JOURNAL OF ALZHEIMERS DISEASE (2009)
Conformational Diversity of Wild-type Tau Fibrils Specified by Templated Conformation Change
Bess Frost et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
(-)-Epigallocatechin-3-Gallate (EGCG) Maintains κ-Casein in Its Pre-Fibrillar State without Redirecting Its Aggregation Pathway
Sean A. Hudson et al.
JOURNAL OF MOLECULAR BIOLOGY (2009)
Resveratrol inhibits beta-amyloid oligomeric cytotoxicity but does not prevent oligomer formation
Ying Feng et al.
NEUROTOXICOLOGY (2009)
Structure-neurotoxicity relationships of amyloid β-protein oligomers
Kenjiro Ono et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Structural Classification of Toxic Amyloid Oligomers
Charles G. Glabe
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Grape-derived polyphenolics prevent Aβ oligomerization and attenuate cognitive deterioration in a mouse model of Alzheimer's disease
Jun Wang et al.
JOURNAL OF NEUROSCIENCE (2008)
EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers
Dagmar E. Ehrnhoefer et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2008)
Direct and selective elimination of specific prions and amyloids by 4,5-dianilinophthalimide and analogs
Huan Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Molecular structural basis for polymorphism in Alzheimer's β-amyloid fibrils
Anant K. Paravastu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Fibrils with parallel in-register structure constitute a major class of amyloid fibrils: molecular insights from electron paramagnetic resonance spectroscopy
Martin Margittai et al.
QUARTERLY REVIEWS OF BIOPHYSICS (2008)
Molecules that target beta-amyloid
Cliff I. Stains et al.
CHEMMEDCHEM (2007)
Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes
Jill C. Milne et al.
NATURE (2007)
Structure-activity relationships of amyloid beta-aggregation inhibitors based on curcumin: Influence of linker length and flexibility
Ashley A. Reinke et al.
CHEMICAL BIOLOGY & DRUG DESIGN (2007)
Investigation of α-synuclein fibril structure by site-directed spin labeling
Min Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Methylene blue inhibits amyloid Aβ oligomerization by promoting fibrillization
Mihaela Necula et al.
BIOCHEMISTRY (2007)
Characterization of the nucleation barriers for protein aggregation and amyloid formation
Stefan Auer et al.
HFSP JOURNAL (2007)
Prion recognition elements govern nucleation, strain specificity and species barriers
Peter M. Tessier et al.
NATURE (2007)
Conformation-sensitive antibodies against Alzheimer amyloid-β by immunization with a thioredoxin-constrained B-cell epitope peptide
Nadia Moretto et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Mechanism of formation of amyloid protofibrils of barstar from soluble oligomers: Evidence for multiple steps and lateral association coupled to conformational conversion
Santosh Kumar et al.
JOURNAL OF MOLECULAR BIOLOGY (2007)
Small molecule inhibitors of aggregation indicate that amyloid β oligomerization and fibrillization pathways are independent and distinct
Mihaela Necula et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Polymorphism in the intermediates and products of amyloid assembly
Ravindra Kodali et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2007)
Inhibitory activity of stilbenes on Alzheimer's β-amyloid fibrils in vitro
Celine Riviere et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2007)
Resveratrol improves health and survival of mice on a high-calorie diet
Joseph A. Baur et al.
NATURE (2006)
Fluorescence correlation spectroscopy shows that monomeric polyglutamine molecules form collapsed structures in aqueous solutions
Scott L. Crick et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Kinetics and thermodynamics of amyloid fibril assembly
Ronald Wetzel
ACCOUNTS OF CHEMICAL RESEARCH (2006)
Opposing activities protect against age-onset proteotoxicity
Ehud Cohen et al.
SCIENCE (2006)
Polymorphic fibril formation by residues 10-40 of the Alzheimer's β-amyloid peptide
Anant K. Paravastu et al.
BIOPHYSICAL JOURNAL (2006)
Characterization of the formation of amyloid protofibrils from barstar by mapping residue-specific fluorescence dynamics
Samrat Mukhopadhyay et al.
JOURNAL OF MOLECULAR BIOLOGY (2006)
Dequalinium-induced protofibril formation of α-synuclein
CH Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Therapeutic approaches to polyglutamine diseases: Combating protein misfolding and aggregation
Martin Herbst et al.
CURRENT PHARMACEUTICAL DESIGN (2006)
Therapeutic potential of resveratrol: the in vivo evidence
Joseph A. Baur et al.
NATURE REVIEWS DRUG DISCOVERY (2006)
3D structure of Alzheimer's amyloid-β(1-42) fibrils
T Lührs et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Molecular-level secondary structure, polymorphism, and dynamics of full-length α-synuclein fibrils studied by solid-state NMR
H Heise et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Polyglutamine aggregation nucleation: Thermodynamics of a highly unfavorable protein folding reaction
AM Bhattacharyya et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Cold-active β-galactosidase from Arthrobacter sp C2-2 forms compact 660 kDa hexamers:: Crystal structure at 1.9 Å resolution
T Skálová et al.
JOURNAL OF MOLECULAR BIOLOGY (2005)
Seeding-dependent propagation and maturation of amyloid fibril conformation
K Yamaguchi et al.
JOURNAL OF MOLECULAR BIOLOGY (2005)
Evidence for a mechanism of amyloid formation involving molecular reorganisation within native-like precursor aggregates
G Plakoutsi et al.
JOURNAL OF MOLECULAR BIOLOGY (2005)
Filaments of the Ure2p prion protein have a cross-β core structure
U Baxa et al.
JOURNAL OF STRUCTURAL BIOLOGY (2005)
Inhibition of heparin-induced tau filament formation by phenothiazines, polyphenols, and porphyrins
S Taniguchi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Curcumin inhibits formation of amyloid β oligomers and fibrils, binds plaques, and reduces amyloid in vivo
FS Yang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Self-propagating, molecular-level polymorphism in Alzheimer's β-amyloid fibrils
AT Petkova et al.
SCIENCE (2005)
Phthalocyanine tetrasulfonates affect the amyloid formation and cytotoxicity of α-synuclein
EN Lee et al.
BIOCHEMISTRY (2004)
Conformational variations in an infectious protein determine prion strain differences
M Tanaka et al.
NATURE (2004)
Amyloid nucleation and hierarchical assembly of Ure2p fibrils - Role of asparagine/glutamine repeat and nonrepeat regions of the prion domain
Y Jiang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Mammalian prion biology: One century of evolving concepts
A Aguzzi et al.
CELL (2004)
Mechanism of prion propagation: Amyloid growth occurs by monomer addition
SR Collins et al.
PLOS BIOLOGY (2004)
Inhibition of islet amyloid polypeptide fibril formation: A potential role for heteroaromatic interactions
Y Porat et al.
BIOCHEMISTRY (2004)
Efficient reversal of Alzheimer's disease fibril formation and elimination of neurotoxicity by a small molecule
BJ Blanchard et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Molecular pathways of neurodegeneration in Parkinson's disease
TM Dawson et al.
SCIENCE (2003)
Potent anti-amyloidogenic and fibril-destabilizing effects of polyphenols in vitro:: implications for the prevention and therapeutics of Alzheimer's disease
K Ono et al.
JOURNAL OF NEUROCHEMISTRY (2003)
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
KT Howitz et al.
NATURE (2003)
Generation of prion transmission barriers by mutational control of amyloid conformations
P Chien et al.
NATURE (2003)
Huntingtin aggregation and toxicity in Huntington's disease
G Bates
LANCET (2003)
Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis
R Kayed et al.
SCIENCE (2003)
The native-like conformation of Ure2p in fibrils assembled under physiologically relevant conditions switches to an amyloid-like conformation upon heat-treatment of the fibrils
L Bousset et al.
JOURNAL OF STRUCTURAL BIOLOGY (2003)
A structural model for Alzheimer's β-amyloid fibrils based on experimental constraints from solid state NMR
AT Petkova et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Structural and dynamic features of Alzheimer's Aβ peptide in amyloid fibrils studied by site-directed spin labeling
M Török et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Huntington's disease age-of-onset linked to polyglutamine aggregation nucleation
SM Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Conformational Abs recognizing a generic amyloid fibril epitope
B O'Nuallain et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
A possible role for pi-stacking in the self-assembly of amyloid fibrils
E Gazit
FASEB JOURNAL (2002)
Amyloid β-protein oligomerization -: Prenucleation interactions revealed by photo-induced cross-linking of unmodified proteins
G Bitan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Parkinson's disease and related neurodegenerative synucleinopathies linked to progressive accumulations of synuclein aggregates in brain
JQ Trojanowski et al.
PARKINSONISM & RELATED DISORDERS (2001)
Conformational diversity in a yeast prion dictates its seeding specificity
P Chien et al.
NATURE (2001)
Nucleated conformational conversion and the replication of conformational information by a prion determinant
TR Serio et al.
SCIENCE (2000)
Amyloid fibrillogenesis: themes and variations
JC Rochet et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2000)
Share Paper
