Related references
Note: Only part of the references are listed.Thioredoxin-interacting protein links oxidative stress to inflammasome activation
Rongbin Zhou et al.
NATURE IMMUNOLOGY (2010)
The Inflammasomes: Guardians of the Body
Fablo Martinon et al.
ANNUAL REVIEW OF IMMUNOLOGY (2009)
Immunological and Inflammatory Functions of the Interleukin-1 Family
Charles A. Dinarello
ANNUAL REVIEW OF IMMUNOLOGY (2009)
Inflammasome-Mediated Disease Animal Models Reveal Roles for Innate but Not Adaptive Immunity
Susannah D. Brydges et al.
IMMUNITY (2009)
A Mutation in the Nlrp3 Gene Causing Inflammasome Hyperactivation Potentiates Th17 Cell-Dominant Immune Responses
Guangxun Meng et al.
IMMUNITY (2009)
Vinyl Sulfones as Antiparasitic Agents and a Structural Basis for Drug Design
Iain D. Kerr et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Glyburide inhibits the Cryopyrin/Nalp3 inflammasome
Mohamed Lamkanfi et al.
JOURNAL OF CELL BIOLOGY (2009)
Cutting Edge: NF-κB Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression
Franz G. Bauernfeind et al.
JOURNAL OF IMMUNOLOGY (2009)
Neisseria gonorrhoeae Activates the Proteinase Cathepsin B to Mediate the Signaling Activities of the NLRP3 and ASC-Containing Inflammasome
Joseph A. Duncan et al.
JOURNAL OF IMMUNOLOGY (2009)
Cutting Edge: Candida albicans Hyphae Formation Triggers Activation of the NlrP3 Inflammasome
Sophie Joly et al.
JOURNAL OF IMMUNOLOGY (2009)
Calcium-Independent Phospholipase A(2)beta Is Dispensable in Inflammasome Activation and Its Inhibition by Bromoenol Lactone
Luigi Franchi et al.
JOURNAL OF INNATE IMMUNITY (2009)
Cholesterol-dependent cytolysins induce rapid release of mature IL-1β from murine macrophages in a NLRP3 inflammasome and cathepsin B-dependent manner
Jessica Chu et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2009)
Sesquiterpene Lactone Parthenolide Ameliorates Bladder Inflammation and Bladder Overactivity in Cyclophosphamide Induced Rat Cystitis Model by Inhibiting Nuclear Factor-κB Phosphorylation
Hiroshi Kiuchi et al.
JOURNAL OF UROLOGY (2009)
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
Teresa Fernandes-Alnemri et al.
NATURE (2009)
Pyroptosis: host cell death and inflammation
Tessa Bergsbaken et al.
NATURE REVIEWS MICROBIOLOGY (2009)
Aryl vinyl Sulfonates and Sulfones as active site-directed and mechanism-based probes for protein tyrosine phosphatases
Sijiu Liu et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
Veit Hornung et al.
NATURE IMMUNOLOGY (2008)
The NALP3 inflammasome is involved in the innate immune response to amyloid-β
Annett Halle et al.
NATURE IMMUNOLOGY (2008)
The Nalp3 inflammasome is essential for the development of silicosis
Suzanne L. Cassel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
The inflammasome:: a danger sensing complex triggering innate immunity
Virginie Petrilli et al.
CURRENT OPINION IN IMMUNOLOGY (2007)
Pyrin activates the ASC pyroptosome in response to engagement by autoinflammatory PSTPIP1 mutants
Je-Wook Yu et al.
MOLECULAR CELL (2007)
The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation
T. Fernandes-Alnemri et al.
CELL DEATH AND DIFFERENTIATION (2007)
Cryopyrin/NALP3 binds ATP/dATP, is an ATPase, and requires ATP binding to mediate inflammatory signaling
Joseph A. Duncan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation
Benjamin Faustin et al.
MOLECULAR CELL (2007)
Vinyl sulfones: Synthetic preparations and medicinal chemistry applications
D. Christopber Meadows et al.
MEDICINAL RESEARCH REVIEWS (2006)
Parthenolide modulates the NF-κB-mediated inflammatory responses in experimental atherosclerosis
Oscar Lopez-Franco et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2006)
Gout-associated uric acid crystals activate the NALP3 inflammasome
F Martinon et al.
NATURE (2006)
Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin
ED Boyden et al.
NATURE GENETICS (2006)
Potentiation of caspase-1 activation by the P2X7 receptor is dependent on TLR signals and requires NF-κB-driven protein synthesis
JM Kahlenberg et al.
JOURNAL OF IMMUNOLOGY (2005)
Vinyl sulfones:: Inhibitors of SrtA, a transpeptidase required for cell wall protein anchoring and virulence in Staphylococcus aureus
BA Frankel et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)
Role of cysteine residues of p65/NF-κB on the inhibition by the sesquiterpene lactone parthenolide and-N-ethyl maleimide, and on its transactivating potential
AJ Garcia-Piñeres et al.
LIFE SCIENCES (2004)
Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes
J Feldmann et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2002)
Parthenolide, an inhibitor of the nuclear factor-κB pathway, ameliorates cardiovascular derangement and outcome in endotoxic shock in rodents
M Sheehan et al.
MOLECULAR PHARMACOLOGY (2002)
Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome
HM Hoffman et al.
NATURE GENETICS (2001)
Cysteine 38 in p65/NF-κB plays a crucial role in DNA binding inhibition by sesquiterpene lactones
AJ García-Piñeres et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
The anti-inflammatory natural product parthenolide from the medicinal herb Feverfew directly binds to and inhibits IκB kinase
BHB Kwok et al.
CHEMISTRY & BIOLOGY (2001)