Related references
Note: Only part of the references are listed.Protein kinase Cγ, a protein causative for dominant ataxia, negatively regulates nuclear import of recessive-ataxia-related aprataxin
Hirohide Asai et al.
HUMAN MOLECULAR GENETICS (2009)
Mutant γPKC found in spinocerebellar ataxia type 14 induces aggregate-independent maldevelopment of dendrites in primary cultured Purkinje cells
Takahiro Seki et al.
NEUROBIOLOGY OF DISEASE (2009)
Trehalose impairs aggregation of PrPSc molecules and protects prion-infected cells against oxidative damage
Florence Beranger et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Enzymological analysis of mutant protein kinase Cγ causing spinocerebellar ataxia type 14 and dysfunction in Ca2+ homeostasis
Naoko Adachi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
PKCγ mutations in spinocerebellar ataxia type 14 affect C1 domain accessibility and kinase activity leading to aberrant MAPK signaling
Dineke S. Verbeek et al.
JOURNAL OF CELL SCIENCE (2008)
Aggregate formation of mutant protein kinase C gamma found in spinocerebellar ataxia type 14 impairs ubiquitin-proteasome system and induces endoplasmic reticulum stress
Takahiro Seki et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2007)
Mutations in TTBK2, encoding a kinase implicated in tau phosphorylation, segregate with spinocerebellar ataxia type 11
Henry Houlden et al.
NATURE GENETICS (2007)
Protection from ataxia-linked apoptosis by gap junction inhibitors
Dingbo Lin et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Benign SCA14 phenotype in a German patient associated with a missense mutation in exon 3 of the PRKCG gene
Stefan Wieczorek et al.
MOVEMENT DISORDERS (2007)
Trehalose transporter 1, a facilitated and high-capacity trehalose transporter, allows exogenous trehalose uptake into cells
Takahiro Kikawada et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Protein kinase C γ mutations in the C1B domain cause caspase-3-linked apoptosis in lens epithelial cells through gap junctions
Dingbo Lin et al.
EXPERIMENTAL EYE RESEARCH (2007)
Another mutation in cysteine 131 in protein kinase Cγ as a cause of spinocerebellar ataxia type 14
Stephan Klebe et al.
ARCHIVES OF NEUROLOGY (2007)
Trehalose effects on α-crystallin aggregates
Francesco Attanasio et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and α-synuclein
Sovan Sarkar et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
The natural osmolyte trehalose is a positive regulator of the heat-induced activity of yeast heat shock transcription factor
Laura K. Conlin et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Spinocerebellar ataxia 14:: Novel mutation in exon 2 of PRKCG in a German family
Dagmar Nolte et al.
MOVEMENT DISORDERS (2007)
Deletion at ITPR1 underlies ataxia in mice and spinocerebellar ataxia 15 in humans
Joyce van de Leemput et al.
PLOS GENETICS (2007)
Fused protein of δPKC activation loop and PDK1-interacting fragment (δAL-PIF) functions as a pseudosubstrate and an inhibitory molecule for PDK1 when expressed in cells
Takahiro Seki et al.
GENES TO CELLS (2006)
Identification of a new family of spinocerebellar ataxia type 14 in the Japanese spinocerebellar ataxia population by the screening of PRKCG exon 4
Keiko Hiramoto et al.
MOVEMENT DISORDERS (2006)
Mutation of the highly conserved cysteine residue 131 of the SCA14 associated PRKCG gene in a family with slow progressive cerebellar ataxia
Andreas Dalski et al.
JOURNAL OF NEUROLOGY (2006)
Novel PRKCG/SCA14 mutation in a Dutch spinocerebellar ataxia family:: Expanding the phenotype
Monique H. M. Vlak et al.
MOVEMENT DISORDERS (2006)
Common mechanisms of amyloid oligomer pathogenesis in degenerative disease
CG Glabe
NEUROBIOLOGY OF AGING (2006)
Trehalose uptake through P2X7 purinergic channels provides dehydration protection
GD Elliott et al.
CRYOBIOLOGY (2006)
Trehalose reduces aggregate formation and delays pathology in a transgenic mouse model of oculopharyngeal muscular dystrophy
JE Davies et al.
HUMAN MOLECULAR GENETICS (2006)
SCA28, a novel form of autosomal dominant cerebellar ataxia on chromosome 18p11.22-q11.2
C Cagnoli et al.
BRAIN (2006)
Molecular pathogenesis of spinocerebellar ataxias
Antoni Matilla Duenas et al.
BRAIN (2006)
Trehalose differentially inhibits aggregation and neurotoxicity of beta-amyloid 40 and 42
R Liu et al.
NEUROBIOLOGY OF DISEASE (2005)
Mutant protein kinase Cγ found in spinocerebellar ataxia type 14 is susceptible to aggregation and causes cell death
T Seki et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
The clinical and genetic spectrum of spinocerebellar ataxia 14
DH Chen et al.
NEUROLOGY (2005)
Protein kinase C gamma mutations in spinocerebellar ataxia 14 increase kinase activity and alter membrane targeting
DS Verbeek et al.
BRAIN (2005)
Trehalose-protein interaction in aqueous solution
RD Lins et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2004)
Trehalose alleviates polyglutamine-mediated pathology in a mouse model of Huntington disease
M Tanaka et al.
NATURE MEDICINE (2004)
Protein aggregation and neurodegenerative disease
CA Ross et al.
NATURE MEDICINE (2004)
Trinucleotide repeats and neurodegenerative disease
CM Everett et al.
BRAIN (2004)
Protein misfolding in neurodegenerative diseases
EI Agorogiannis et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2004)
Autosomal dominant cerebellar ataxias:: clinical features, genetics, and pathogenesis
L Schöls et al.
LANCET NEUROLOGY (2004)
Missense mutations in the regulatory domain of PKCγ:: A new mechanism for dominant nonepisodic cerebellar ataxia
DH Chen et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2003)
Trehalose: a review of properties, history of use and human tolerance, and results of multiple safety studies
AB Richards et al.
FOOD AND CHEMICAL TOXICOLOGY (2002)
Biomedicine - Toxic proteins in neurodegenerative disease
JP Taylor et al.
SCIENCE (2002)