Related references
Note: Only part of the references are listed.DEPTOR Is an mTOR Inhibitor Frequently Overexpressed in Multiple Myeloma Cells and Required for Their Survival
Timothy R. Peterson et al.
CELL (2009)
mTORC2 regulates PGE2-mediated endothelial cell survival and migration
Shirine Dada et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1)
Juan M. Garcia-Martinez et al.
BIOCHEMICAL JOURNAL (2008)
Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling
Tsuneo Ikenoue et al.
EMBO JOURNAL (2008)
The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C
Valeria Facchinetti et al.
EMBO JOURNAL (2008)
mTOR inhibitors in the treatment of cancer
Angelica Fasolo et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2008)
mTOR-raptor binds and activates SGK1 to regulate p27 phosphorylation
Feng Hong et al.
MOLECULAR CELL (2008)
Mammalian Rho GTPases:: new insights into their functions from in vivo studies
Sarah J. Heasman et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
Rapamycin inhibits F-actin reorganization and phosphorylation of focal adhesion proteins
L. Liu et al.
ONCOGENE (2008)
PRR5, a novel component of mTOR complex 2, regulates platelet-derived growth factor receptor β expression and signaling
So-Yon Woo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
PRAS40 is a target for mammalian target of rapamycin complex 1 and is required for signaling downstream of this complex
Bruno D. Fonseca et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
P-Rex1 links mammalian target of rapamycin signaling to Rac activation and cell migration
Ivette Hernandez-Negrete et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Identification of Protor as a novel Rictor-binding component of mTOR complex-2
Laura R. Pearce et al.
BIOCHEMICAL JOURNAL (2007)
PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase
Yasemin Sancak et al.
MOLECULAR CELL (2007)
Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40
Emilie Vander Haar et al.
NATURE CELL BIOLOGY (2007)
Rapamycin inhibits cell motility by suppression of mTOR-mediated S6K1 and 4E-BP1 pathways
L. Liu et al.
ONCOGENE (2006)
Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity
Qian Yang et al.
GENES & DEVELOPMENT (2006)
SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity
Estela Jacinto et al.
CELL (2006)
Integrin-regulated FAK-Src signaling in normal and cancer cells
Satyajit K. Mitra et al.
CURRENT OPINION IN CELL BIOLOGY (2006)
Ribosome biogenesis and cell growth: mTOR coordinates transcription by all three classes of nuclear RNA polymerases
C. Mayer et al.
ONCOGENE (2006)
mSin1 is necessary for Akt/PKB phosphorylation, and its isoforms define three distinct mTORC2s
Maria A. Frias et al.
CURRENT BIOLOGY (2006)
Genetic deletion of Rac1 GTPase reveals its critical role in actin stress fiber formation and focal adhesion complex assembly
Fukun Guo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Spatiotemporal dynamics of RhoA activity in migrating cells
O Pertz et al.
NATURE (2006)
Role of small GTPases in endothelial cytoskeletal dynamics and the shear stress response
E Tzima
CIRCULATION RESEARCH (2006)
Localized RhoA activation as a requirement for the induction of membrane ruffling
K Kurokawa et al.
MOLECULAR BIOLOGY OF THE CELL (2005)
Characterization of a conserved c-terminal motif (RSPRR) in ribosomal protein S6-kinase-1 required for its mammalian target of rapamycin-dependent regulation
SS Schalm et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
DD Sarbassov et al.
SCIENCE (2005)
Stent implantation activates RhoA in human arteries: Inhibitory effect of rapamycin
P Guerin et al.
JOURNAL OF VASCULAR RESEARCH (2005)
Translation of the radioresistance kinase TLK1B is induced by γ-irradiation through activation of mTOR and phosphorylation of 4E-BP1 -: art. no. 1
G Sunavala-Dossabhoy et al.
BMC MOLECULAR BIOLOGY (2004)
Involvement of Rho family GTPases in p19Arf-and p53-mediated proliferation of primary mouse embryonic fibroblasts
FK Guo et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton
DD Sarbassov et al.
CURRENT BIOLOGY (2004)
Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive
E Jacinto et al.
NATURE CELL BIOLOGY (2004)
RhoA induces MMP-9 expression at CD44 lamellipodial focal complexes and promotes HMEC-1 cell invasion
I Abécassis et al.
EXPERIMENTAL CELL RESEARCH (2003)
IGF-II transcription in skeletal myogenesis is controlled by mTOR and nutrients
E Erbay et al.
JOURNAL OF CELL BIOLOGY (2003)
Targeting mTOR signaling for cancer therapy
S Huang et al.
CURRENT OPINION IN PHARMACOLOGY (2003)
P19Arf-p53 tumor suppressor pathway regulates cell motility by suppression of phosphoinositide 3-kinase and Rac1 GTPase activities
FK Guo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
GβL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR
DH Kim et al.
MOLECULAR CELL (2003)
The rapamycin-binding domain governs substrate selectivity by the mammalian target of rapamycin
LP McMahon et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control
R Loewith et al.
MOLECULAR CELL (2002)
The immuno suppress ant rapamycin mimics a starvation-like signal distinct from amino acid and glucose deprivation
T Peng et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action
K Hara et al.
CELL (2002)
MTOR interacts with Raptor to form a nutrient-sensitive complex that signals to the cell growth machinery
DH Kim et al.
CELL (2002)
Myogenic differentiation is dependent on both the kinase function and the N-terminal sequence of mammalian target of rapamycin
LL Shu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
The mammalian target of rapamycin regulates C2C12 myogenesis via a kinase-independent mechanism
E Erbay et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Mammalian target of rapamycin-dependent phosphorylation of PHAS-I in four (S/T)P sites detected by phospho-specific antibodies
I Mothe-Satney et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
RhoA function in lamellae formation and migration is regulated by the α6β4 integrin and cAMP metabolism
KL O'Connor et al.
JOURNAL OF CELL BIOLOGY (2000)