Related references
Note: Only part of the references are listed.Protein phosphatase-1 regulates Akt1 signal transduction pathway to control gene expression, cell survival and differentiation
L. Xiao et al.
CELL DEATH AND DIFFERENTIATION (2010)
Mechanisms of Life Span Extension by Rapamycin in the Fruit Fly Drosophila melanogaster
Ivana Bjedov et al.
CELL METABOLISM (2010)
Branched-Chain Amino Acid Supplementation Promotes Survival and Supports Cardiac and Skeletal Muscle Mitochondrial Biogenesis in Middle-Aged Mice
Giuseppe D'Antona et al.
CELL METABOLISM (2010)
Regulation of mTOR Complex 1 (mTORC1) by Raptor Ser(863) and Multisite Phosphorylation
Kathryn G. Foster et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
A Role for p38 Stress-Activated Protein Kinase in Regulation of Cell Growth via TORC1
Megan Cully et al.
MOLECULAR AND CELLULAR BIOLOGY (2010)
Insulin mediates the linkage acceleration of muscle protein synthesis, thermogenesis, and heat storage by amino acids
Ippei Yamaoka et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)
Association of apolipoprotein E polymorphisms and dietary factors in colorectal cancer
M. Mrkonjic et al.
BRITISH JOURNAL OF CANCER (2009)
Bidirectional Transport of Amino Acids Regulates mTOR and Autophagy
Paul Nicklin et al.
CELL (2009)
DEPTOR Is an mTOR Inhibitor Frequently Overexpressed in Multiple Myeloma Cells and Required for Their Survival
Timothy R. Peterson et al.
CELL (2009)
A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance
Christopher B. Newgard et al.
CELL METABOLISM (2009)
Nutritional and contractile regulation of human skeletal muscle protein synthesis and mTORC1 signaling
Micah J. Drummond et al.
JOURNAL OF APPLIED PHYSIOLOGY (2009)
The Transcription of FOXO Genes Is Stimulated by FOXO3 and Repressed by Growth Factors
Ahmed Essaghir et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
mTOR signaling at a glance
Mathieu Laplante et al.
JOURNAL OF CELL SCIENCE (2009)
Regulation of mTORC1 and mTORC2 Complex Assembly by Phosphatidic Acid: Competition with Rapamycin
Alfredo Toschi et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
Amino-acid imbalance explains extension of lifespan by dietary restriction in Drosophila
Richard C. Grandison et al.
NATURE (2009)
Tumours with PI3K activation are resistant to dietary restriction
Nada Y. Kalaany et al.
NATURE (2009)
Ribosomal Protein S6 Kinase 1 Signaling Regulates Mammalian Life Span
Colin Selman et al.
SCIENCE (2009)
New Insights into mTOR Signaling: mTORC2 and Beyond
Dario R. Alessi et al.
SCIENCE SIGNALING (2009)
Targeting PI3K signalling in cancer: opportunities, challenges and limitations
Jeffrey A. Engelman
NATURE REVIEWS CANCER (2009)
mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1)
Juan M. Garcia-Martinez et al.
BIOCHEMICAL JOURNAL (2008)
ERK and p38 pathways regulate amino acid signalling
Eduard Casas-Terradellas et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2008)
Amino acids activate mTOR Complex 1 via Ca2+/CaM signaling to hVps34
Pawan Gulati et al.
CELL METABOLISM (2008)
Re-evaluating the Roles of Proposed Modulators of Mammalian Target of Rapamycin Complex 1 (mTORC1) Signaling
Xuemin Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
The TSC1-TSC2 complex is required for proper activation of mTOR complex 2
Jingxiang Huang et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
Structure/function relationships underlying regulation of FOXO transcription factors
T. Obsil et al.
ONCOGENE (2008)
FOXOs, cancer and regulation of apoptosis
Z. Fu et al.
ONCOGENE (2008)
Akt2 overexpression plays a critical role in the establishment of colorectal cancer metastasis
Piotr G. Rychahou et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
High red meat diets induce greater numbers of colonic DNA double-strand breaks than white meat in rats: attenuation by high-amylose maize starch
Shusuke Toden et al.
CARCINOGENESIS (2007)
Autophagy: from phenomenology to molecular understanding in less than a decade
Daniel J. Klionsky
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Identification of Protor as a novel Rictor-binding component of mTOR complex-2
Laura R. Pearce et al.
BIOCHEMICAL JOURNAL (2007)
Dynamic FoxO transcription factors
Haojie Huang et al.
JOURNAL OF CELL SCIENCE (2007)
Nutrient signalling in the regulation of human muscle protein synthesis
Satoshi Fujita et al.
JOURNAL OF PHYSIOLOGY-LONDON (2007)
Evidence for functional redundancy of class IA PI3K isoforms in insulin signalling
Claire Chaussade et al.
BIOCHEMICAL JOURNAL (2007)
mTOR Complex1-S6K1 signaling: at the crossroads of obesity, diabetes and cancer
Stephen G. Dann et al.
TRENDS IN MOLECULAR MEDICINE (2007)
PHA-4/Foxa mediates diet-restriction-induced longevity of C-elegans
Siler H. Panowski et al.
NATURE (2007)
A MAP4 kinase related to Ste20 is a nutrient-sensitive regulator of mTOR signalling
Greg M. Findlay et al.
BIOCHEMICAL JOURNAL (2007)
Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCα but not S6K1
David A. Guertin et al.
DEVELOPMENTAL CELL (2006)
SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity
Estela Jacinto et al.
CELL (2006)
A selective inhibitor of the p110δ isoform of PI 3-kinase inhibits AML cell proliferation and survival and increases the cytotoxic effects of VP16
C. Billottet et al.
ONCOGENE (2006)
Insulin and amino-acid regulation of mTOR signaling and kinase activity through the Rheb GTPase
J. Avruch et al.
ONCOGENE (2006)
Simultaneous electrophoretic analysis of proteins of very high and low molecular weights using low-percentage acrylamide gel and a gradient SDS-PAGE gel
Eduard Casas-Terradellas et al.
ELECTROPHORESIS (2006)
Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB
DD Sarbassov et al.
MOLECULAR CELL (2006)
TOR signaling in growth and metabolism
S Wullschleger et al.
CELL (2006)
TOR signaling in growth and metabolism
Stephan Wullschleger et al.
CELL (2006)
Nutrient overload, insulin resistance, and ribosomal protein S6 kinase 1, S6K1
Sung Hee Um et al.
CELL METABOLISM (2006)
Growing roles for the mTOR pathway
DD Sarbassov et al.
CURRENT OPINION IN CELL BIOLOGY (2005)
Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 30H-kinase
T Nobukuni et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
hVps34 is a nutrient-regulated lipid kinase required for activation of p70 S6 kinase
MP Byfield et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
PI 3-kinase p110β:: a new target for antithrombotic therapy
SP Jackson et al.
NATURE MEDICINE (2005)
Distinct signaling events downstream of mTOR cooperate to mediate the effects of amino acids and insulin on initiation factor 4E-binding proteins
XM Wang et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
DD Sarbassov et al.
SCIENCE (2005)
Mammalian target of rapamycin regulates IRS-1 serine 307 phosphorylation
CJ Carlson et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
Amino acids and insulin control autophagic proteolysis through different signaling pathways in relation to mTOR in isolated rat hepatocytes
T Kanazawa et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
A library of siRNA duplexes targeting the phosphoinositide 3-kinase pathway: determinants of gene silencing for use in cell-based screens
AC Hsieh et al.
NUCLEIC ACIDS RESEARCH (2004)
Regulation of protein synthesis by branched-chain amino acids in vivo
F Yoshizawa
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
Overweight, obesity and cancer: Epidemiological evidence and proposed mechanisms
EE Calle et al.
NATURE REVIEWS CANCER (2004)
Design, synthesis, and biological activity of novel, potent, and selective (benzoylaminomethyl)thiophene sulfonamide inhibitors of c-jun-N-terminal kinase
T Rückle et al.
JOURNAL OF MEDICINAL CHEMISTRY (2004)
Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton
DD Sarbassov et al.
CURRENT BIOLOGY (2004)
The TSC1-2 tumor suppressor controls insulin-PI3K signaling via regulation of IRS proteins
LS Harrington et al.
JOURNAL OF CELL BIOLOGY (2004)
Regulation and role of autophagy in mammalian cells
AJ Meijer et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2004)
Target of rapamycin (TOR)-signaling and RAIP motifs play distinct roles in the mammalian TOR-dependent phosphorylation of initiation factor 4E-binding protein 1
A Beugnet et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Selective role of PI3Kδ in neutrophil inflammatory responses
C Sadhu et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
The mammalian target of rapamycin (mTOR) partner, raptor, binds the mTOR substrates p70 S6 kinase and 4E-BP1 through their TOR signaling (TOS) motif
H Nojima et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Regulation of cell survival and proliferation by the FOXO (Forkhead box, class 0) subfamily of forkhead transcription factors
KU Birkenkamp et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2003)
Dietary energy restriction in breast cancer prevention
HJ Thompson et al.
JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA (2003)
MTOR interacts with Raptor to form a nutrient-sensitive complex that signals to the cell growth machinery
DH Kim et al.
CELL (2002)
Mammalian target of rapamycin pathway regulates insulin signaling via subcellular redistribution of insulin receptor substrate 1 and integrates nutritional signals and metabolic signals of insulin
T Takano et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
Y Kabeya et al.
EMBO JOURNAL (2000)
A rapamycin-sensitive pathway down-regulates insulin signaling via phosphorylation and proteasomal degradation of insulin receptor substrate-1
T Haruta et al.
MOLECULAR ENDOCRINOLOGY (2000)
Share Paper
