Related references
Note: Only part of the references are listed.First evidence that the antimalarial drug artesunate inhibits invasion and in vivo metastasis in lung cancer by targeting essential extracellular proteases
Suhail Ahmed Kabeer Rasheed et al.
INTERNATIONAL JOURNAL OF CANCER (2010)
HGF-induced invasion by prostate tumor cells requires anterograde lysosome trafficking and activity of Na+-H+ exchangers
Joshua J. Steffan et al.
JOURNAL OF CELL SCIENCE (2010)
Dihydroartemisinin inhibits growth of pancreatic cancer cells in vitro and in vivo
Hua Chen et al.
ANTI-CANCER DRUGS (2009)
Gene expression profiling identifies novel key players involved in the cytotoxic effect of Artesunate on pancreatic cancer cells
Mahmoud Youns et al.
BIOCHEMICAL PHARMACOLOGY (2009)
Lysosomal involvement in cell death and cancer
Thomas Kirkegaard et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2009)
The Role of Downstream Signaling Pathways of the Epidermal Growth Factor Receptor for Artesunate's Activity in Cancer Cells
V. Badireenath Konkimalla et al.
CURRENT CANCER DRUG TARGETS (2009)
Coordination of membrane events during autophagy by multiple class III PI3-kinase complexes
Anne Simonsen et al.
JOURNAL OF CELL BIOLOGY (2009)
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
Daniel J. Klionsky et al.
AUTOPHAGY (2008)
Dual contrasting roles of cysteine cathepsins in cancer progression: Apoptosis versus tumour invasion
Olga Vasiljeva et al.
BIOCHIMIE (2008)
Artesunate derived from traditional Chinese medicine induces DNA damage and repair
Paul C. H. Li et al.
CANCER RESEARCH (2008)
Experimental therapy of hepatoma with artemisinin and its derivatives:: In vitro and in vivo activity, chemosensitization, and mechanisms of action
Junmei Hou et al.
CLINICAL CANCER RESEARCH (2008)
Pharmacokinetics and tolerability of artesunate and amodiaquine alone and in combination in healthy volunteers
Catherine Orrell et al.
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY (2008)
Mitochondrial dynamics and apoptosis
Der-Fen Suen et al.
GENES & DEVELOPMENT (2008)
Translocation of Iron from Lysosomes into Mitochondria Is a Key Event During Oxidative Stress-Induced Hepatocellular Injury
Akira Uchiyama et al.
HEPATOLOGY (2008)
Lysosomes in iron metabolism, ageing and apoptosis
Tino Kurz et al.
HISTOCHEMISTRY AND CELL BIOLOGY (2008)
Cysteine cathepsins trigger caspase-dependent cell death through cleavage of Bid and antiapoptotic Bcl-2 homologues
Gabriela Droga-Mazovec et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Rab5 modulates aggregation and toxicity of mutant huntingtin through macroautophagy in cell and fly models of Huntington disease
Brinda Ravikumar et al.
JOURNAL OF CELL SCIENCE (2008)
Targeting lysosomal degradation induces p53-dependent cell death and prevents cancer in mouse models of lymphomagenesis
Kirsteen H. Maclean et al.
JOURNAL OF CLINICAL INVESTIGATION (2008)
Caspase-8 is activated by cathepsin D initiating neutrophil apoptosis during the resolution of inflammation
Sebastien Conus et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
Lysosomal membrane permeabilization in cell death
P. Boya et al.
ONCOGENE (2008)
The itinerary of autophagosomes: From peripheral formation to kiss-and-run fusion with lysosomes
Luca Jahreiss et al.
TRAFFIC (2008)
Tumor necrosis factor-related apoptosis-inducing ligand activates a lysosomal pathway of apoptosis that is regulated by Bcl-2 proteins
Nathan W. Werneburg et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Role of Transferrin Receptor and the ABC Transporters ABCB6 and ABCB7 for Resistance and Differentiation of Tumor Cells towards Artesunate
Gerhard Kelter et al.
PLOS ONE (2007)
Artesunate Induces ROS-Mediated Apoptosis in Doxorubicin-Resistant T Leukemia Cells
Thomas Efferth et al.
PLOS ONE (2007)
Autophagy, ageing and apoptosis: The role of oxidative stress and lysosomal iron
Tino Kurz et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2007)
Cathepsin-cleaved Bid promotes apoptosis in human neutrophils via oxidative stress-induced lysosomal membrane permeabilization
Robert Blomgran et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2007)
MitoNEET is an iron-containing outer mitochondrial membrane protein that regulates oxidative capacity
Sandra E. Wiley et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Anti-malarial agent artesunate inhibits TNF-alpha-induced production of proinflammatory cytokines via inhibition of NF-kappa B and PI3 kinase/Akt signal pathway in human rheumatoid arthritis fibroblast-like synoviocytes
H. Xu et al.
RHEUMATOLOGY (2007)
Response to myocardial ischemia/reperfusion injury involves Bnip3 and autophagy
A. Hamacher-Brady et al.
CELL DEATH AND DIFFERENTIATION (2007)
The mitogen-activated protein kinase pathway can inhibit TRAIL-induced apoptosis by prohibiting association of truncated Bid with mitochondria
G. Ortiz-Ferron et al.
CELL DEATH AND DIFFERENTIATION (2006)
Enhancing macroautophagy protects against ischemia/reperfusion injury in cardiac myocytes
Anne Hamacher-Brady et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Proapoptotic BCL-2 family members and mitochondrial dysfunction during ischemia/reperfusion injury, a study employing cardiac HL-1 cells and GFP biosensors
Nathan R. Brady et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2006)
Bafilomycin A1 inhibits chloroquine-induced death of cerebellar granule neurons
JJ Shacka et al.
MOLECULAR PHARMACOLOGY (2006)
Molecular pharmacology and pharmacogenomics of artemisinin and its derivatives in cancer cells
T Efferth
CURRENT DRUG TARGETS (2006)
Bid, a BH3-only multi-functional molecule, is at the cross road of life and death
XM Yin
GENE (2006)
Kinesin-2 is a motor for late endosomes and lysosomes
CL Brown et al.
TRAFFIC (2005)
Lysosomes and autophagy in cell death control
G Kroemer et al.
NATURE REVIEWS CANCER (2005)
Expression of estrogen receptor α, retinoic acid receptor α and cellular retinoic acid binding protein II genes is coordinately regulated in human breast cancer cells
M Lu et al.
ONCOGENE (2005)
Effects of artemisinin-tagged holotransferrin on cancer cells
H Lai et al.
LIFE SCIENCES (2005)
Selective disruption of lysosomes in HeLa cells triggers apoptosis mediated by cleavage of bid by multiple papain-like lysosomal cathepsins
T Cirman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Enhancement of cytotoxicity of artemisinins toward cancer cells by ferrous iron
T Efferth et al.
FREE RADICAL BIOLOGY AND MEDICINE (2004)
Role for Rab7 in maturation of late autophagic vacuoles
S Jäger et al.
JOURNAL OF CELL SCIENCE (2004)
TNF-α-mediated lysosomal permeabilization is FAN and caspase 8/Bid dependent
N Werneburg et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2004)
Inhibition of angiogenesis in vivo and growth of Kaposi's sarcoma xenograft tumors by the anti-malarial artesunate
R Dell'Eva et al.
BIOCHEMICAL PHARMACOLOGY (2004)
Apoptosis of human umbilical vein endothelial cells induced by artesunate
GD Wu et al.
VASCULAR PHARMACOLOGY (2004)
Antimalarial drug toxicity - A review
WRJ Taylor et al.
DRUG SAFETY (2004)
Molecular modes of action of artesunate in tumor cell lines
T Efferth et al.
MOLECULAR PHARMACOLOGY (2003)
Mitochondrial membrane permeabilization is a critical step of lysosome-initiated apoptosis induced by hydroxychloroquine
P Boya et al.
ONCOGENE (2003)
Lysosomal membrane permeabilization induces cell death in a mitochondrion-dependent fashion
P Boya et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
A fluorescence microplate assay using yopro-1 to measure apoptosis: Application to HL60 cells subjected to oxidative stress
E Plantin-Carrenard et al.
CELL BIOLOGY AND TOXICOLOGY (2003)
Tumor necrosis factor-α-associated lysosomal permeabilization is cathepsin B dependent
NW Werneburg et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2002)
Selective toxicity of dihydroartemisinin and holotransferrin toward human breast cancer cells
NP Singh et al.
LIFE SCIENCES (2001)
Rab proteins as membrane organizers
M Zerial et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2001)
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
Y Kabeya et al.
EMBO JOURNAL (2000)
Cathepsin B contributes to TNF-α-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c
ME Guicciardi et al.
JOURNAL OF CLINICAL INVESTIGATION (2000)
Rab7: A key to lysosome biogenesis
C Bucci et al.
MOLECULAR BIOLOGY OF THE CELL (2000)