Related references
Note: Only part of the references are listed.STIM1 converts TRPC1 from a receptor-operated to a store-operated channel: Moving TRPC1 in and out of lipid rafts
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Lipid rafts determine clustering of STIM1 in endoplasmic reticulum-plasma membrane junctions and regulation of store-operated Ca2+ entry (SOCE)
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Canonical transient receptor potential 5 channel in conjunction with Orai1 and STIM1 allows Sr2+ entry, optimal influx of Ca2+, and degranulation in a rat mast cell line
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Functional interactions among Orai1, TRPCs, and STIM1 suggest a STIM-regulated heteromeric Orai/TRPC model for SOCE/Icrac channels
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Local Ca2+ influx through Ca2+ release-activated Ca2+ (CRAC) channels stimulates production of an intracellular messenger and an intercellular pro-inflammatory signal
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Attenuation of store-operated Ca2+ current impairs salivary gland fluid secretion in TRPC1(-/-) mice
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TRPC channels as STIM1 - regulated store-operated channels
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TRPC1: The link between functionally distinct store-operated calcium channels
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Biochemical properties and cellular localisation of STIM proteins
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Molecular basis of the CRAC channel
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Dynamic assembly of TRPC1-STIM1-Orai1 ternary complex is involved in store-operated calcium influx - Evidence for similarities in store-operated and calcium release-activated calcium channel components
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Orai proteins interact with TRPC channels and confer responsiveness to store depletion
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STIM1 heteromultimerizes TRPC channels to determine their function as store-operated channels
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Failure of calcium microdomain generation and pathological consequences
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CRACM1 multimers form the ion-selective pore of the CRAC channel
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Orai1 is an essential pore subunit of the CRAC channel
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Molecular identification of the CRAC channel by altered ion selectivity in a mutant of Orai
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Large store-operated calcium selective currents due to co-expression of Orai1 or Orai2 with the intracellular calcium sensor, Stim1
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Orai1 and STIM reconstitute store-operated calcium channel function
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JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Amplification of CRAC current by STIM1 and CRACM1 (Orai1)
Christine Peinelt et al.
NATURE CELL BIOLOGY (2006)
Genome-wide RNAi screen of Ca2+ influx identifies genes that regulate Ca2+ release-activated Ca2+ channel activity
Shenyuan L. Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
CRACM1 is a plasma membrane protein essential for store-operated Ca2+ entry
M. Vig et al.
SCIENCE (2006)
A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function
S Feske et al.
NATURE (2006)
STIM1 carboxyl-terminus activates native SOC, I-crac and TRPC1 channels
Guo N. Huang et al.
NATURE CELL BIOLOGY (2006)
Endogenous TRPC1, TRPC3, and TRPC7 proteins combine to form native store-operated channels in HEK-293 cells
TK Zagranichnaya et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx
J Liou et al.
CURRENT BIOLOGY (2005)
STIM1, an essential and conserved component of store-operated Ca2+ channel function
J Roos et al.
JOURNAL OF CELL BIOLOGY (2005)
Close functional coupling between Ca2+ release-activated Ca2+ channels, arachidonic acid release, and leukotriene C4 secretion
WC Chang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Activation of the TRPC1 cation channel by metabotropic glutamate receptor mGluR1
SJ Kim et al.
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Homer binds TRPC family channels and is required for gating of TRPC1 by IP3 receptors
JP Yuan et al.
CELL (2003)
TRPC3 mediates T-cell receptor-dependent calcium entry in human T-lymphocytes
S Philipp et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Permeation through store-operated CRAC channels in divalent-free solution: potential problems and implications for putative CRAC channelgenes
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CELL CALCIUM (2002)
Lack of an endothelial store-operated Ca2+ current impairs agonist-dependent vasorelaxation in TRP4-/- mice
M Freichel et al.
NATURE CELL BIOLOGY (2001)