Related references
Note: Only part of the references are listed.Template Usage Is Responsible for the Preferential Acquisition of the K65R Reverse Transcriptase Mutation in Subtype C Variants of Human Immunodeficiency Virus Type 1
Dimitrios Coutsinos et al.
JOURNAL OF VIROLOGY (2009)
The A62V and S68G mutations in HIV-1 reverse transcriptase partially restore the replication defect associated with the K65R mutation
Evguenia S. Svarovskaia et al.
JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES (2008)
Molecular basis of antagonism between K70E and K65R tenofovir-associated mutations in HIV-1 reverse transcriptase
R. M. Kagan et al.
ANTIVIRAL RESEARCH (2007)
Molecular mechanisms of bidirectional antagonism between K65R and thymidine analog mutations in HIV-1 reverse transcriptase
Urvi M. Parikh et al.
AIDS (2007)
Crystal structures of clinically relevant Lys103Asn/Tyr181Cys double mutant HIV-1 reverse transcriptase in complexes with ATP and non-nucleoside inhibitor HBY 097
Kalyan Das et al.
JOURNAL OF MOLECULAR BIOLOGY (2007)
Site-directed mutagenesis in the fingers subdomain of HIV-1 reverse transcriptase reveals a specific role for the β3-β4 hairpin loop in dNTP selection
Scott J. Garforth et al.
JOURNAL OF MOLECULAR BIOLOGY (2007)
Version 1.2 of the Crystallography and NMR system
Axel T. Brunger
NATURE PROTOCOLS (2007)
Molecular mechanism by which the K70E mutation in human immunodeficiency virus type 1 reverse transcriptase confers resistance to nucleoside reverse transcriptase inhibitors
Nicolas Sluis-Cremer et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2007)
Resistance development over 144 weeks in treatment-naive patients receiving tenofovir disoproxil fumarate or stavudine with lamivudine and efavirenz in Study 903
N. A. Margot et al.
HIV MEDICINE (2006)
The K65R mutation in human immunodeficiency virus type 1 reverse transcriptase exhibits bidirectional phenotypic antagonism with thymidine analog mutations
Urvi M. Parikh et al.
JOURNAL OF VIROLOGY (2006)
A combination of decreased NRTI incorporation and decreased excision determines the resistance profile of HIV-1K65R RT
KL White et al.
AIDS (2005)
Stereo-selectivity of HIV-1 reverse transcriptase toward isomers of thymidine-5′-O-1-thiotriphosphate
J Radzio et al.
PROTEIN SCIENCE (2005)
Replication-dependent 65R→K reversion in human immunodeficiency virus type 1 reverse transcriptase double mutant K65R+L74V
PL Sharma et al.
VIROLOGY (2004)
Molecular mechanisms of tenofovir resistance conferred by human immunodeficiency virus type 1 reverse transcriptase containing a diserine insertion, after residue 69 and multiple thymidine analog-associated mutations
KL White et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2004)
Mechanistic basis for reduced viral and enzymatic fitness of HIV-1 reverse transcriptase containing both K65R and M184V mutations
J Deval et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Coot:: model-building tools for molecular graphics
P Emsley et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2004)
A loss of viral replicative capacity correlates with altered DNA polymerization kinetics by the human immunodeficiency virus reverse transcriptase bearing the K65R and L74V dideoxynucleoside resistance substitutions
J Deval et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Structures of HIV-1 RT-DNA complexes before and after incorporation of the anti-AIDS drug tenofovir
S Tuske et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2004)
Broad nucleoside reverse-transcriptase inhibitor cross-resistance in human immunodeficiency virus type 1 clinical isolates
JM Whitcomb et al.
JOURNAL OF INFECTIOUS DISEASES (2003)
Site-specific footprinting reveals differences in the translocation status of HIV-1 reverse transcriptase -: Implications for polymerase translocation and drug resistance
B Marchand et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Relationship between 3′-azido-3′-deoxythymidine resistance and primer unblocking activity in foscarnet-resistant mutants of human immunodeficiency virus type 1 reverse transcriptase
PR Meyer et al.
JOURNAL OF VIROLOGY (2003)
Trapping HIV-1 reverse transcriptase before and after translocation on DNA
SG Sarafianos et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
The hydration structure of guanidinium and thiocyanate ions: Implications for protein stability in aqueous solution
PE Mason et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Effects of dipeptide insertions between codons 69 and 70 of human immunodeficiency virus type 1 reverse transcriptase on primer unblocking, deoxynucleoside triphosphate inhibition, and DNA chain elongation
PR Meyer et al.
JOURNAL OF VIROLOGY (2003)
Molecular mechanisms of resistance to human immunodeficiency virus type 1 with reverse transcriptase mutations K65R and K65R+M184V and their effects on enzyme function and viral replication capacity
KL White et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2002)
The CCP4 molecular-graphics project
E Potterton et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2002)
Nucleoside analog resistance caused by insertions in the fingers of human immunodeficiency virus type 1 reverse transcriptase involves ATP-mediated excision
PL Boyer et al.
JOURNAL OF VIROLOGY (2002)
Mechanism-based suppression of dideoxynucleotide resistance by K65R human immunodeficiency virus reverse transcriptase using an α-boranophosphate nucleoside analogue
B Selmi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Selective excision of AZTMP by drug-resistant human immunodeficiency virus reverse transcriptase
PL Boyer et al.
JOURNAL OF VIROLOGY (2001)
Role of a dipeptide insertion between codons 69 and 70 of HIV-1 reverse transcriptase in the mechanism of AZT resistance
A Mas et al.
EMBO JOURNAL (2000)
In vitro selection of mutations in the human immunodeficiency virus type 1 reverse transcriptase that decrease susceptibility to (-)-β-D-dioxolane-guanosine and suppress resistance to 3′-azido-3′-deoxythymidine
HZ Bazmi et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2000)
Mutational analysis of Lys65 of HIV-1 reverse transcriptase
N Sluis-Cremer et al.
BIOCHEMICAL JOURNAL (2000)
Resistance profile of the human immunodeficiency virus type 1 reverse transcriptase inhibitor abacavir (1592U89) after monotherapy and combination therapy
PR Harrigan et al.
JOURNAL OF INFECTIOUS DISEASES (2000)
Share Paper
