4.6 Article

Inhibition of Heterotrimeric G Protein Signaling by a Small Molecule Acting on Gα Subunit

Related references

Note: Only part of the references are listed.
Article Pharmacology & Pharmacy

The novel inhibitor of the heterotrimeric G-protein complex, BIM-46187, elicits anti-hyperalgesic properties and synergizes with morphine

Christine Favre-Guilmard et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2008)

Review Oncology

G-protein-coupled receptors and cancer

Robert T. Dorsam et al.

NATURE REVIEWS CANCER (2007)

Article Biochemistry & Molecular Biology

Asymmetric conformational changes in a GPCR dimer controlled by G-proteins

Marjorie Damian et al.

EMBO JOURNAL (2006)

Article Biotechnology & Applied Microbiology

Opinion - How many drug targets are there?

John P. Overington et al.

NATURE REVIEWS DRUG DISCOVERY (2006)

Review Biochemistry & Molecular Biology

Latest development in drug discovery on G protein-coupled receptors

Kenneth Lundstrom

CURRENT PROTEIN & PEPTIDE SCIENCE (2006)

Article Biochemistry & Molecular Biology

Probing the activation-promoted structural rearrangements in preassembled receptor-G protein complexes

Celine Gales et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2006)

Article Biochemistry & Molecular Biology

Mechanism of the receptor-catalyzed activation of heterotrimeric G proteins

William M. Oldham et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2006)

Article Multidisciplinary Sciences

Differential targeting of Gβγ-subunit signaling with small molecules

TM Bonacci et al.

SCIENCE (2006)

Article Multidisciplinary Sciences

Heterotrimeric G proteins precouple with G protein-coupled receptors in living cells

M Nobles et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Article Biochemical Research Methods

Real-time monitoring of receptor and G-protein interactions in living cells

C Galés et al.

NATURE METHODS (2005)

Article Biochemistry & Molecular Biology

Dynamics of arrestin-rhodopsin interactions - Arrestin and retinal release are directly linked events

ME Sommer et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Biochemistry & Molecular Biology

A novel Gαq/11-selective inhibitor

J Takasaki et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Biotechnology & Applied Microbiology

YM-254890, a novel platelet aggregation inhibitor produced by Chromobacterium sp QS3666

M Taniguchi et al.

JOURNAL OF ANTIBIOTICS (2003)

Article Endocrinology & Metabolism

Oxytocin and vasopressin V1a and V2 receptors form constitutive homo- and heterodimers during biosynthesis

S Terrillon et al.

MOLECULAR ENDOCRINOLOGY (2003)

Review Biochemical Research Methods

Constitutively active G protein-coupled receptor mutants: Implications on receptor function and drug action

S Cotecchia et al.

ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES (2003)

Review Biotechnology & Applied Microbiology

Regulators of G-protein signalling as new central nervous system drug targets

RR Neubig et al.

NATURE REVIEWS DRUG DISCOVERY (2002)

Article Pharmacology & Pharmacy

Activation and inhibition of G proteins by lipoamines

E Breitweg-Lehmann et al.

MOLECULAR PHARMACOLOGY (2002)

Article Biochemistry & Molecular Biology

Dramatic mitochondrial gene rearrangements in the hermit crab Pagurus longicarpus (Crustacea, Anomura)

MJ Hickerson et al.

MOLECULAR BIOLOGY AND EVOLUTION (2000)