4.6 Article

BRI3 Inhibits Amyloid Precursor Protein Processing in a Mechanistically Distinct Manner from Its Homologue Dementia Gene BRI2

Related references

Note: Only part of the references are listed.
Article Neurosciences

BRI2 (ITM2b) inhibits Aβ deposition in vivo

Jungsu Kim et al.

JOURNAL OF NEUROSCIENCE (2008)

Article Biochemistry & Molecular Biology

Regulated intramembrane proteolysis of Bri2 (Itm2b) by ADAM10 and SPPL2a/SPPL2b

Lucas Martin et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Clinical Neurology

The γ/ε-secretase-derived APP intracellular domain fragments regulate p53

Frederic Checler et al.

CURRENT ALZHEIMER RESEARCH (2007)

Article Biochemistry & Molecular Biology

Amyloid precursor protein intracellular domain modulates cellular calcium homeostasis and ATP content

Runa Hamid et al.

JOURNAL OF NEUROCHEMISTRY (2007)

Article Multidisciplinary Sciences

The presenilin hypothesis of Alzheimer's disease: Evidence for a loss-of-function pathogenic mechanism

Jie Shen et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Biochemistry & Molecular Biology

BRI2 interacts with amyloid precursor protein (APP) and regulates amyloid β (Aβ) production

A Fotinopoulou et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Biochemistry & Molecular Biology

The familial dementia BRI2 gene binds the Alzheimer gene amyloid-β precursor protein and inhibits amyloid-β production

S Matsuda et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Biochemistry & Molecular Biology

γ-secretase exists on the plasma membrane as an intact complex that accepts substrates and effects intramembrane cleavage

JH Chyung et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Biochemistry & Molecular Biology

Cleavage of amyloid-β precursor protein and amyloid-β precursor-like protein by BACE 1

QM Li et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Multidisciplinary Sciences

JNK-interacting protein-1 promotes transcription of Aβ protein precursor but not Aβ precursor-like proteins, mechanistically different than Fe65

MH Scheinfeld et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Article Biochemistry & Molecular Biology

Processing of β-amyloid precursor-like protein-1 and-2 by γ-secretase regulates transcription

MH Scheinfeld et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Biochemistry & Molecular Biology

BRICHOS:: a conserved domain in proteins associated with dementia, respiratory distress and cancer

L Sánchez-Pulido et al.

TRENDS IN BIOCHEMICAL SCIENCES (2002)

Article Multidisciplinary Sciences

The γ-secretase-generated intracellular domain of β-amyloid precursor protein binds Numb and inhibits Notch signaling

R Roncarati et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

Article Multidisciplinary Sciences

A physiologic signaling role for the γ-secretase-derived intracellular fragment of APP

MA Leissring et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

Review Neurosciences

γ-Secretase, notch, Aβ and Alzheimer's disease:: Where do the presenilins fit in?

SS Sisodia et al.

NATURE REVIEWS NEUROSCIENCE (2002)

Article Multidisciplinary Sciences

A decamer duplication in the 3′ region of the BRI gene originates an amyloid peptide that is associated with dementia in a Danish kindred

R Vidal et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)