Related references
Note: Only part of the references are listed.A helix-to-coil transition at the ε-cut site in the transmembrane dimer of the amyloid precursor protein is required for proteolysis
Takeshi Sato et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Dimerization of the transmembrane domain of amyloid precursor proteins and familial Alzheimer's disease mutants
Paul M. Gorman et al.
BMC NEUROSCIENCE (2008)
A closer look at α-secretase
Rolf Postina
CURRENT ALZHEIMER RESEARCH (2008)
Homophilic interactions of the amyloid precursor protein (APP) ectodomain are regulated by the loop region and affect β-secretase cleavage of APP
Daniela Kaden et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Amyloidogenic processing but not amyloid precursor protein (APP) intracellular C-terminal domain production requires a precisely oriented APP dimer assembled by transmembrane GXXXG motifs
Pascal Kienlen-Campard et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Flotillin-dependent clustering of the amyloid precursor protein regulates its endocytosis and amyloidogenic processing in neurons
Anja Schneider et al.
JOURNAL OF NEUROSCIENCE (2008)
A TAG1-APP signalling pathway through Fe65 negatively modulates neurogenesis
Quan-Hong Ma et al.
NATURE CELL BIOLOGY (2008)
Secreted APP regulates the function of full-length APP in neurite outgrowth through interaction with integrin beta1
Tracy L. Young-Pearse et al.
NEURAL DEVELOPMENT (2008)
ADAM-10 over-expression increases cortical synaptogenesis
Karen F. S. Bell et al.
NEUROBIOLOGY OF AGING (2008)
A critical function for β-amyloid precursor protein in neuronal migration revealed by In Utero RNA interference
Tracy L. Young-Pearse et al.
JOURNAL OF NEUROSCIENCE (2007)
Structure and functions of the human amyloid precursor protein: The whole is more than the sum of its parts
Matthias Gralle et al.
PROGRESS IN NEUROBIOLOGY (2007)
GxxxG motifs within the amyloid precursor protein transmembrane sequence are critical for the etiology of Aβ42
Lisa-Marie Munter et al.
EMBO JOURNAL (2007)
Imaging molecular interactions in living cells by FRET microscopy
Elizabeth A. Jares-Erijman et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2006)
Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer's disease brain is associated with mitochondrial dysfunction
Latha Devi et al.
JOURNAL OF NEUROSCIENCE (2006)
Synapse formation and function is modulated by the amyloid precursor protein
Christina Priller et al.
JOURNAL OF NEUROSCIENCE (2006)
Innovating lifetime microscopy: a compact and simple tool for life sciences, screening, and diagnostics
Alessandro Esposito et al.
JOURNAL OF BIOMEDICAL OPTICS (2006)
Visualization of APP dimerization and APP-Notch2 heterodimerization in living cells using bimolecular fluorescence complementation
CD Chen et al.
JOURNAL OF NEUROCHEMISTRY (2006)
Solution conformation and heparin-induced dimerization of the full-length extracellular domain of the human amyloid precursor protein
M Gralle et al.
JOURNAL OF MOLECULAR BIOLOGY (2006)
A dark yellow fluorescent protein (YFP)-based Resonance Energy-Accepting Chromoprotein (REACh) for Forster resonance energy transfer with GFP
S Ganesan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Covalent labeling of cell-surface proteins for in-vivo FRET studies
BH Meyer et al.
FEBS LETTERS (2006)
Alzheimer precursor protein interaction with the Nogo-66 receptor reduces amyloid-β plaque deposition
JH Park et al.
JOURNAL OF NEUROSCIENCE (2006)
APP locus duplication causes autosomal dominant early-onset Alzheimer disease with cerebral amyloid angiopathy
A Rovelet-Lecrux et al.
NATURE GENETICS (2006)
Fluorescence lifetime heterogeneity resolution in the frequency domain by lifetime moments analysis
A Esposito et al.
BIOPHYSICAL JOURNAL (2005)
Homo- and heterodimerization of APP family members promotes intercellular adhesion
P Soba et al.
EMBO JOURNAL (2005)
Superresolution by localization of quantum dots using blinking statistics
KA Lidke et al.
OPTICS EXPRESS (2005)
Amyloid precursor protein promotes post-developmental neurite arborization in the Drosophila brain
M Leyssen et al.
EMBO JOURNAL (2005)
Reaching out for signals: filopodia sense EGF and respond by directed retrograde transport of activated receptors
DS Lidke et al.
JOURNAL OF CELL BIOLOGY (2005)
Defective neuromuscular synapses in mice lacking amyloid precursor protein (APP) and APP-like protein 2
P Wang et al.
JOURNAL OF NEUROSCIENCE (2005)
Neutralization of transthyretin reverses the neuroprotective effects of secreted amyloid precursor protein (APP) in APPSw mice resulting in tau phosphorylation and loss of hippocampal neurons:: Support for the amyloid hypothesis
TD Stein et al.
JOURNAL OF NEUROSCIENCE (2004)
The X-ray structure of an antiparaliel dimer of the human amyloid precursor protein E2 domain
YC Wang et al.
MOLECULAR CELL (2004)
Three-dimensional structure of an independently folded extracellular domain of human amyloid-β precursor protein
I Dulubova et al.
BIOCHEMISTRY (2004)
Specific labeling of cell surface proteins with chemically diverse compounds
N George et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)
Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp red fluorescent protein
NC Shaner et al.
NATURE BIOTECHNOLOGY (2004)
Synaptic targeting by Alzheimer's-related amyloid β oligomers
PN Lacor et al.
JOURNAL OF NEUROSCIENCE (2004)
Cortical dysplasia resembling human type 2 lissencephaly in mice lacking all three APP family members
J Herms et al.
EMBO JOURNAL (2004)
The β-amyloid precursor protein controls a store-operated Ca2+ entry in cortical neurons
A Bouron et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2004)
A disintegrin-metalloproteinase prevents amyloid plaque formation and hippocampal defects in an Alzheimer disease mouse model
R Postina et al.
JOURNAL OF CLINICAL INVESTIGATION (2004)
Alzheimer's disease-affected brain:: Presence of oligomeric Aβ ligands (ADDLs) suggests a molecular basis for reversible memory loss
YS Gong et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
The cytoplasmic domain of Alzheimer's amyloid-β protein precursor causes sustained apoptosis signal-regulating kinase 1/c-Jun NH2-terminal kinase-mediated neurotoxic signal via dimerization
Y Hashimoto et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2003)
The receptor-bound N-terminal ectodomain of the amyloid precursor protein is associated with membrane rafts
R Tikkanen et al.
BIOLOGICAL CHEMISTRY (2002)
Solution studies and structural model of the extracellular domain of the human amyloid precursor protein
M Gralle et al.
BIOPHYSICAL JOURNAL (2002)
Amyloid precursor protein family-induced neuronal death is mediated by impairment of the neuroprotective calcium/calmodulin protein kinase IV-dependent signaling pathway
C Mbebi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Partitioning of lipid-modified monomeric GFPs into membrane microdomains of live cells
DA Zacharias et al.
SCIENCE (2002)
Homodimerization of amyloid precursor protein and its implication in the amyloidogenic pathway of Alzheimer's disease
S Scheuermann et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Secreted Aβ does not mediate neurotoxicity by antibody-stimulated amyloid precursor protein
H Sudo et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)
Antibody-regulated neurotoxic function of cell-surface ß-amyloid precursor protein
H Sudo et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2000)
Brain glucose and energy metabolism abnormalities in sporadic Alzheimer disease. Causes and consequences: an update
S Hoyer
EXPERIMENTAL GERONTOLOGY (2000)
A monoclonal antibody to amyloid precursor protein induces neuronal apoptosis
TT Rohn et al.
JOURNAL OF NEUROCHEMISTRY (2000)
Protein kinase C-dependent α-secretase competes with β-secretase for cleavage of amyloid-β precursor protein in the trans-Golgi network
DM Skovronsky et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Levels of α- and β-secretase cleaved amyloid precursor protein in the cerebrospinal fluid of Alzheimer's disease patients
K Sennvik et al.
NEUROSCIENCE LETTERS (2000)
Share Paper
