Related references
Note: Only part of the references are listed.S1219 residue of 53BP1 is phosphorylated by ATM kinase upon DNA damage and required for proper execution of DNA damage response
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53BP1 facilitates long-range DNA end-joining during V(D)J recombination
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Distinct roles of chromatin-associated proteins MDC1 and 53BP1 in mammalian double-strand break repair
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The tandem BRCT domain of 53BP1 is not required for its repair function
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53BP1 contributes to survival of cells irradiated with X-ray during G1 without Ku70 or Artemis
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Genetic dissection of vertebrate 53BP1: A major role in non-homologous end joining of DNA double strand breaks
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A phosphatase complex that dephosphorylates γH2AX regulates DNA damage checkpoint recovery
MC Keogh et al.
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γ-H2AX dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair
D Chowdhury et al.
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Protein phosphatase 5 is required for ATR-mediated checkpoint activation
J Zhang et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
53BP1 cooperates with p53 and functions as a haploinsufficient tumor suppressor in mice
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DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
J Bartkova et al.
NATURE (2005)
DNA-PKcs function regulated specifically by protein phosphatase 5
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Requirement of protein phosphatase 5 in DNA-damage-induced ATM activation
A Ali et al.
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53BP1, an activator of ATM in response to DNA damage
TA Mochan et al.
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A pathway of double-strand break rejoining dependent upon ATM, artemis, and proteins locating to γ-H2AX foci
E Riballo et al.
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Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks
Y Huyen et al.
NATURE (2004)
53BP1 is required for class switch recombination
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DNA end joining becomes less efficient and more error-prone during cellular senescence
A Seluanov et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination
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Potential role for 53BP1 in DNA end-joining repair through direct interaction with DNA
K Iwabuchi et al.
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Accumulation of checkpoint protein 53BP1 at DNA breaks involves its binding to phosphorylated histone H2AX
IM Ward et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Role for the BRCA1 C-terminal repeats (BRCT) protein 53BP1 in maintaining genomic stability
JC Morales et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1
O Fernandez-Capetillo et al.
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53BP1 functions in an ATM-dependent checkpoint pathway that is constitutively activated in human cancer
RA DiTullio et al.
NATURE CELL BIOLOGY (2002)
53BP1, a mediator of the DNA damage checkpoint
B Wang et al.
SCIENCE (2002)
Negative feedback regulation of ASK1 by protein phosphatase 5 (PP5) in response to oxidative stress
K Morita et al.
EMBO JOURNAL (2001)
Tumor suppressor p53 binding protein 1 (53BP1) is involved in DNA damage-signaling pathways
I Rappold et al.
JOURNAL OF CELL BIOLOGY (2001)
DNA double-strand breaks: signaling, repair and the cancer connection
KK Khanna et al.
NATURE GENETICS (2001)
Protein phosphatase 5 in signal transduction
M Chinkers
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p53 Binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks
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JOURNAL OF CELL BIOLOGY (2000)
A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage
TT Paull et al.
CURRENT BIOLOGY (2000)
Mechanisms of DNA double-strand break repair and their potential to induce chromosomal aberrations
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MUTAGENESIS (2000)