Related references
Note: Only part of the references are listed.The malin-laforin complex suppresses the cellular toxicity of misfolded proteins by promoting their degradation through the ubiquitin-proteasome system
Punitee Garyali et al.
HUMAN MOLECULAR GENETICS (2009)
Deletions and missense mutations of EPM2A exacerbate unfolded protein response and apoptosis of neuronal cells induced by endoplasm reticulum stress
Yan Liu et al.
HUMAN MOLECULAR GENETICS (2009)
Lafora Progressive Myoclonus Epilepsy: A Meta-analysis of Reported Mutations in the First Decade following the Discovery of the EPM2A and NHLRC1 Genes
Shweta Singh et al.
HUMAN MUTATION (2009)
AMP-activated Protein Kinase Phosphorylates R5/PTG, the Glycogen Targeting Subunit of the R5/PTG-Protein Phosphatase 1 Holoenzyme, and Accelerates Its Down-regulation by the Laforin-Malin Complex
Santiago Vernia et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Regulation of glycogen synthesis by the laforin-malin complex is modulated by the AMP-activated protein kinase pathway
Maria Carmen Solaz-Fuster et al.
HUMAN MOLECULAR GENETICS (2008)
Malin decreases glycogen accumulation by promoting the degradation of protein targeting to glycogen (PTG)
Carolyn A. Worby et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Mechanism suppressing glycogen synthesis in neurons and its demise in progressive myoclonus epilepsy
David Vilchez et al.
NATURE NEUROSCIENCE (2007)
A role for AGL ubiquitination in the glycogen storage disorders of Lafora and Cori's disease
Alan Cheng et al.
GENES & DEVELOPMENT (2007)
Lafora disease proteins malin and laforin are recruited to aggresomes in response to proteasomal impairment
Shuchi Mittal et al.
HUMAN MOLECULAR GENETICS (2007)
Glycogen metabolism in tissues from a mouse model of Lafora disease
Wei Wang et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2007)
Advances in Lafora progressive myoclonus epilepsy
Antonio V. Delgado-Escueta
CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS (2007)
A century-old debate on protein aggregation and neurodegeneration enters the clinic
Peter T. Lansbury et al.
NATURE (2006)
Novel NHLRC1 mutations and genotype-phenotype correlations in patients with Lafora's progressive myoclonic epilepsy
S. Singh et al.
JOURNAL OF MEDICAL GENETICS (2006)
Novel glycogen synthase kinase 3 and ubiquitination pathways in progressive myoclonus epilepsy
H Lohi et al.
HUMAN MOLECULAR GENETICS (2005)
Insights into Lafora disease: Malin is an E3 ubiquitin ligase that ubiquitinates and promotes the degradation of laforin
MS Gentry et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Co-chaperone CHIP associates with expanded polyglutamine protein and promotes their degradation by proteasomes
NR Jana et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Modulation of neurodegeneration by molecular chaperones
PJ Muchowski et al.
NATURE REVIEWS NEUROSCIENCE (2005)
Prediction of sequence-dependent and mutational effects on the aggregation of peptides and proteins
AM Fernandez-Escamilla et al.
NATURE BIOTECHNOLOGY (2004)
Inhibition of proteasomal activity causes inclusion formation in neuronal and non-neuronal cells overexpressing Parkin
HC Ardley et al.
MOLECULAR BIOLOGY OF THE CELL (2003)
Mutations in NHLRC1 cause progressive myoclonus epilepsy
EM Chan et al.
NATURE GENETICS (2003)
CHIP: a quality-control E3 ligase collaborating with molecular chaperones
S Murata et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2003)
Parkin accumulation in aggresomes due to proteasome impairment
E Junn et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity
Y Imai et al.
MOLECULAR CELL (2002)
Biomedicine - Toxic proteins in neurodegenerative disease
JP Taylor et al.
SCIENCE (2002)
Hassles with taking out the garbage: Aggravating aggresomes
R Garcia-Mata et al.
TRAFFIC (2002)
The ubiquitin-proteasome proteolytic pathway: Destruction for the sake of construction
MH Glickman et al.
PHYSIOLOGICAL REVIEWS (2002)
CHIP is a chaperone-dependent E3 ligase that ubiquitylates unfolded protein
S Murata et al.
EMBO REPORTS (2001)
Lafora's disease: Towards a clinical, pathologic, and molecular synthesis
BA Minassian
PEDIATRIC NEUROLOGY (2001)
Impairment of the ubiquitin-proteasome system by protein aggregation
NF Bence et al.
SCIENCE (2001)
Aggresomes, inclusion bodies and protein aggregation
RR Kopito
TRENDS IN CELL BIOLOGY (2000)
Laforin, defective in the progressive myoclonus epilepsy of Lafora type, is a dual-specificity phosphatase associated with polyribosomes
S Ganesh et al.
HUMAN MOLECULAR GENETICS (2000)
Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase
H Shimura et al.
NATURE GENETICS (2000)
Share Paper
