Journal
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 59, Issue 8, Pages 4375-4378Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.00553-15
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Funding
- Cleveland Department of Veterans Affairs (VA)
- Geriatric Research Education and Clinical Center VISN [10]
- VA Merit Review Program [1I01BX001974]
- National Institute of Allergy and Infectious Diseases of the National Institutes of Health (NIH) [R01AI063517, R01AI10056]
- Antibiotic Resistance Leadership Group (from NIH) [UM1AI104681]
- Clinical and Translational Science Collaborative of Cleveland (from the National Center for Advancing Translational Sciences) [UL1TR000439]
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Carbapenem-resistant Enterobacteriaceae (CRE) usually infect patients with significant comorbidities and health care exposures. We present a case of a pregnant woman who developed community-acquired pyelonephritis caused by KPC-producing Klebsiella pneumoniae. Despite antibiotic treatment, she experienced spontaneous prolonged rupture of membranes, with eventual delivery of a healthy infant. This report demonstrates the challenge that CRE may pose to the effective treatment of common infections in obstetric patients, with potentially harmful consequences to maternal and neonatal health.
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