Related references
Note: Only part of the references are listed.Group VI phospholipases A2:: Homeostatic Phospholipases with significant potential as targets for novel therapeutics
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Ceramide forms channels in mitochondrial outer membranes at physiologically relevant concentrations
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Apoptosis of insulin-secreting cells induced by endoplasmic reticulum stress is amplified by overexpression of group VIA calcium-independent phospholipase A2 (iPLA2β) and suppressed by inhibition of iPLA2β
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Palmitate inhibition of insulin gene expression is mediated at the transcriptional level via ceramide synthesis
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Ceramide increases mitochondrial free calcium levels via caspase 8 and Bid: role in initiation of cell death
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beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes
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Na/Ca exchanger overexpression induces endoplasmic reticulum-related apoptosis and caspase-12 activation in insulin-releasing BRIN-BD11 cells
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Targeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetes
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