4.6 Article

Ubiquitin ligase Smurf1 mediates tumor necrosis factor-induced systemic bone loss by promoting proteasomal degradation of bone morphogenetic signaling proteins

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Autoinhibition of the HECT-Type ubiquitin ligase smurf2 through its c2 domain

Silke Wiesner et al.

Article Biochemistry & Molecular Biology

TNF-α inhibits BMP-induced osteoblast differentiation through activating SAPK/JNK signaling

Tomoyuki Mukai et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)

Article Endocrinology & Metabolism

Endogenous TNFα lowers maximum peak bone mass and inhibits osteoblastic smad activation through NF-κB

Yan Li et al.

JOURNAL OF BONE AND MINERAL RESEARCH (2007)

Article Biochemistry & Molecular Biology

Balancing BMP signaling through integrated inputs into the Smad1 linker

Gopal Sapkota et al.

MOLECULAR CELL (2007)

Article Biochemistry & Molecular Biology

Tumor necrosis factor promotes Runx2 degradation through up-regulation of Smurf1 and Smurf2 in osteoblasts

H Kaneki et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Article Biochemistry & Molecular Biology

Smad6 interacts with Runx2 and mediates Smad ubiquitin regulatory factor 1-induced Runx2 degradation

R Shen et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Article Multidisciplinary Sciences

Activation of the E3 ubiquitin ligase Itch through a phosphorylation-induced conformational change

E Gallagher et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Biochemistry & Molecular Biology

Negative regulation of the E3 ubiquitin ligase itch via Fyn-mediated tyrosine phosphorylation

C Yang et al.

MOLECULAR CELL (2006)

Article Biochemistry & Molecular Biology

Smurf1 inhibits osteoblast differentiation and bone formation in vitro and in vivo

M Zhao et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Review Biochemistry & Molecular Biology

Regulation of the TGFβ signalling pathway by ubiquitin-mediated degradation

L Izzi et al.

ONCOGENE (2004)

Article Cell Biology

Bone morphogenetic proteins

D Chen et al.

GROWTH FACTORS (2004)

Article Endocrinology & Metabolism

Inflammatory mediators as essential elements in bone remodeling

SR Goldring

CALCIFIED TISSUE INTERNATIONAL (2003)

Article Biochemistry & Molecular Biology

Disruption of Mekk2 in mice reveals an unexpected role for MEKK2 in modulating T-cell receptor signal transduction

ZJ Guo et al.

MOLECULAR AND CELLULAR BIOLOGY (2002)

Article Biochemistry & Molecular Biology

Expression of the osteoblast differentiation factor RUNX2 (Cbfa1/AML3/Pebp2αA) is inhibited by tumor necrosis factor-α

L Gilbert et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Multidisciplinary Sciences

Identification of ubiquitin ligases required for skeletal muscle atrophy

SC Bodine et al.

SCIENCE (2001)

Article Endocrinology & Metabolism

Inhibition of osteoblast differentiation by tumor necrosis factor-α

L Gilbert et al.

ENDOCRINOLOGY (2000)