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Sensors, Transducers, and Effectors That Regulate Cell Size and Shape

Journal

JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 284, Issue 11, Pages 6595-6599

Publisher

AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC
DOI: 10.1074/jbc.R800049200

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Funding

  1. Canadian Cystic Fibrosis Foundation
  2. Heart and Stroke Foundation of Ontario
  3. Canadian Institutes of Health Research
  4. National Science and Engineering Research Council

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Cell volume and shape are stringently regulated. This homeostasis requires the cells to sense their size and shape and to convey this information to effectors that will counteract deformations induced by osmotic or mechanical challenges. The sensors, transducers, and effectors of volume change are the subject of this review.

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