4.6 Article

Role of JNK translocation to mitochondria leading to inhibition of mitochondria bioenergetics in acetaminophen-induced liver injury

Related references

Note: Only part of the references are listed.
Article Pharmacology & Pharmacy

Mitochondrial Bax translocation accelerates DNA fragmentation and cell necrosis in a murine model of acetaminophen hepatotoxicity

Mary Lynn Bajt et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2008)

Review Biochemistry & Molecular Biology

The c-jun kinase/stress-activated pathway: Regulation, function and role in human disease

Gary L. Johnson et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2007)

Article Gastroenterology & Hepatology

Critical role of c-jun (NH2) terminal kinase in paracetamol-induced acute liver failure

Neil C. Henderson et al.

Article Gastroenterology & Hepatology

Regulation of hepatocyte apoptosis by oxidative stress

Rajat Singh et al.

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2007)

Article Gastroenterology & Hepatology

Mitochondrial protection by the JNK inhibitor leflunomide rescues mice from acetaminophen-induced liver injury

Calivarathan Latchoumycandane et al.

HEPATOLOGY (2007)

Article Biochemistry & Molecular Biology

Sustained JNK activation in response to tumor necrosis factor is mediated by caspases in a cell type-specific manner

Andreas Wicovsky et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Review Pharmacology & Pharmacy

Reactive oxygen species in mitochondria-mediated cell death

Sten Orrenius

DRUG METABOLISM REVIEWS (2007)

Article Cell Biology

The JNK signal transduction pathway

Claire R. Weston et al.

CURRENT OPINION IN CELL BIOLOGY (2007)

Review Cell Biology

The role of the mitochondrial permeability transition in cell death

Jeffrey S. Armstrong

MITOCHONDRION (2006)

Article Biochemistry & Molecular Biology

Hydrogen peroxide and redox modulation sensitize primary mouse hepatocytes to TNF-induced apoptosis

Derick Han et al.

FREE RADICAL BIOLOGY AND MEDICINE (2006)

Review Cell Biology

ADAMs as mediators of EGF receptor transactivation by G protein-coupled receptors

Haruhiko Ohtsu et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2006)

Article Gastroenterology & Hepatology

c-jun N-terminal kinase plays a major role in murine acetaminophen hepatotoxicity

Basuki K. Gunawan et al.

GASTROENTEROLOGY (2006)

Article Medicine, Research & Experimental

Role of caspases in acetaminophen-induced liver injury

H Jaeschke et al.

LIFE SCIENCES (2006)

Review Gastroenterology & Hepatology

Apoptosis and necrosis in the liver: A tale of two deaths?

H Malhi et al.

HEPATOLOGY (2006)

Article Cell Biology

Further study on the role of HSP70 on Ca2+ homeostasis in rat ventricular myocytes subjected to simulated ischemia

J Liu et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2006)

Article Gastroenterology & Hepatology

JNK1 but not JNK2 promotes the development of steatohepatitis in mice

JM Schattenberg et al.

HEPATOLOGY (2006)

Review Biotechnology & Applied Microbiology

Idiosyncratic drug hepatotoxicity

N Kaplowitz

NATURE REVIEWS DRUG DISCOVERY (2005)

Review Pharmacology & Pharmacy

Hepatic mitochondrial glutathione: transport and role in disease and toxicity

JC Femandez-Checa et al.

TOXICOLOGY AND APPLIED PHARMACOLOGY (2005)

Article Biochemistry & Molecular Biology

JNK promotes Bax translocation to mitochondria through phosphorylation of 14-3-3 proteins

F Tsuruta et al.

EMBO JOURNAL (2004)

Article Biochemistry & Molecular Biology

JNK-dependent release of mitochondrial protein, Smac, during apoptosis in multiple myeloma (MM) cells

D Chauhan et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Biochemistry & Molecular Biology

Voltage-dependent anion channels control the release of the superoxide anion from mitochondria to cytosol

D Han et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Review Biochemistry & Molecular Biology

Regulation of cell apoptosis by protein kinase c delta

C Brodie et al.

APOPTOSIS (2003)

Article Biochemistry & Molecular Biology

Activation of the p38 signaling pathway by heat shock involves the dissociation of glutathione S-transferase Mu from Ask1

S Dorion et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Review Gastroenterology & Hepatology

Biochemical and cellular mechanisms of toxic liver injury

N Kaplowitz

SEMINARS IN LIVER DISEASE (2002)

Article Biochemistry & Molecular Biology

Direct activation of mitochondrial apoptosis machinery by c-Jun N-terminal kinase in adult cardiac myocytes

H Aoki et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Chemistry, Medicinal

A protective role for cyclooxygenase-2 in drug-induced liver injury in mice

TP Reilly et al.

CHEMICAL RESEARCH IN TOXICOLOGY (2001)

Article Biochemistry & Molecular Biology

Role for mitochondrial oxidants as regulators of cellular metabolism

S Nemoto et al.

MOLECULAR AND CELLULAR BIOLOGY (2000)

Article Biochemistry & Molecular Biology

Translocation of SAPK/JNK to mitochondria and interaction with Bcl-xL in response to DNA damage

S Kharbanda et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)