Related references
Note: Only part of the references are listed.Src family kinases: Regulation of their activities, levels and identification of new pathways
Evan Ingley
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Lyn regulates BCR-ABL and Gab2 tyrosine phosphorylation and c-Cbl protein stability in imatinib-resistant chronic myelogenous leukemia cells
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BLOOD (2008)
Proteomic analysis of the venom of Heterometrus longimanus (Asian black scorpion)
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Csk-binding protein mediates sequential enzymatic down-regulation and degradation of Lyn in erythropoietin-stimulated cells
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JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Src family kinases phosphorylate the Bcr-Abl SH3-SH2 region and modulate Bcr-Abl transforming activity
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JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias
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Lyn deficiency reduces GATA-1, EKLF and STAT5, and induces extramedullary stress erythropoiesis
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Lyn is a target gene for prostate cancer:: Sequence-based inhibition induces regression of human tumor xenografts
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CANCER RESEARCH (2004)
Discovery of N-(2-chloro-6-methylphenyl)-2-(6-(4-(2-hydroxyethyl)-piperazin-1-yl)-2-methylpyrimidin-4-ylamino)thiazole-5-carboxamide (BMS-354825), a dual Src/Abl kinase inhibitor with potent antitumor activity in preclinical assays
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JOURNAL OF MEDICINAL CHEMISTRY (2004)
Perturbed myelo/erythropoiesis in Lyn-deficient mice is similar to that in mice lacking the inhibitory phosphatases SHP-1 and SHIP-1
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BLOOD (2004)
Overriding imatinib resistance with a novel ABL kinase inhibitor
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SCIENCE (2004)
Short interfering RNA (siRNA) targeting the Lyn kinase induces apoptosis in primary, and drug-resistant, BCR-ABL1(+) leukemia cells
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NATURE MEDICINE (2004)
Src family kinases, key regulators of signal transduction
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ONCOGENE (2004)
Lyn tyrosine kinase regulates thrombopoietin-induced proliferation of hematopoietic cell lines and primary megakaryocytic progenitors
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Dual-specific Src and Abl kinase inhibitors, PP1 and CGP76030, inhibit growth and survival of cells expressing imatinib mesylate-resistant Bcr-Abl kinases
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BCR-ABL independence and LYN kinase overexpression in chronic myelogenous leukemia cells selected for resistance to STI571
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Selective pyrrolo-pyrimidine inhibitors reveal a necessary role for Src family kinases in Bcr-Abl signal transduction and oncogenesis
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JAKs, STATs and Src kinases in hematopoiesis
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ONCOGENE (2002)
Thyroid hormone receptor-interacting protein 1 modulates cytokine and nuclear hormone signaling in erythroid cells
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JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia.
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NEW ENGLAND JOURNAL OF MEDICINE (2001)
Neutral endopeptidase inhibits prostate cancer cell migration by blocking focal adhesion kinase signaling
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JOURNAL OF CLINICAL INVESTIGATION (2000)
Structural mechanism for STI-571 inhibition of Abelson tyrosine kinase
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SCIENCE (2000)
HS1 interacts with Lyn and is critical for erythropoietin-induced differentiation of erythroid cells
E Ingley et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)