Related references
Note: Only part of the references are listed.Tumor-derived mutations in the TRAIL receptor DR5 inhibit TRAIL signaling through the DR4 receptor by competing for ligand binding
Lianghua Bin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases
Michal Szczepek et al.
NATURE BIOTECHNOLOGY (2007)
Computer modelling in combination with in vitro studies reveals similar binding affinities of Drosophila Crumbs for the PDZ domains of Stardust and DmPar-6
Ozlem Kempkens et al.
EUROPEAN JOURNAL OF CELL BIOLOGY (2006)
Designed tumor necrosis factor-related apoptosis-inducing ligand variants initiating apoptosis exclusively via the DR5 receptor
Almer M. van der Sloot et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
TRAIL receptor-selective mutants signal to apoptosis via TRAIL-R1 in primary lymphoid malignancies
M MacFarlane et al.
CANCER RESEARCH (2005)
Prediction of water and metal binding sites and their affinities by using the Fold-X force field
JWH Schymkowitz et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Chronic lymphocytic leukemic cells exhibit apoptotic signaling via TRAIL-R1
M MacFarlane et al.
CELL DEATH AND DIFFERENTIATION (2005)
Recognizing and defining true Ras binding domains II:: In silico prediction based on homology modelling and energy calculations
C Kiel et al.
JOURNAL OF MOLECULAR BIOLOGY (2005)
Recognizing and defining true Ras binding domains 1:: Biochemical analysis
S Wohlgemuth et al.
JOURNAL OF MOLECULAR BIOLOGY (2005)
Receptor-selective mutants of apoptosis-inducing ligand 2/tumor necrosis factor-related apoptosis-inducing ligand reveal a greater contribution
RF Kelley et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Computational redesign of protein-protein interaction specificity
T Kortemme et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2004)
Stabilization of TRAIL, an all-β-sheet multimeric protein, using computational redesign
AM van der Sloot et al.
PROTEIN ENGINEERING DESIGN & SELECTION (2004)
A detailed thermodynamic analysis of Ras/effector complex interfaces
C Kiel et al.
JOURNAL OF MOLECULAR BIOLOGY (2004)
TRAIL and its receptors as targets for cancer therapy
H Yagita et al.
CANCER SCIENCE (2004)
Following a TRAIL: Update on a ligand and its five receptors
FC Kimberley et al.
CELL RESEARCH (2004)
Inactivation of TNF signaling by rationally designed dominant-negative TNF variants
PM Steed et al.
SCIENCE (2003)
Apo2L/TRAIL and its death and decoy receptors
HN LeBlanc et al.
CELL DEATH AND DIFFERENTIATION (2003)
Automated design of specificity in molecular recognition
JJ Havranek et al.
NATURE STRUCTURAL BIOLOGY (2003)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences
RL Strausberg et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Modulating calmodulin binding specificity through computational protein design
JM Shifman et al.
JOURNAL OF MOLECULAR BIOLOGY (2002)
Predicting changes in the stability of proteins and protein complexes: A study of more than 1000 mutations
R Guerois et al.
JOURNAL OF MOLECULAR BIOLOGY (2002)
Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8.
FC Kischkel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity
K Ichikawa et al.
NATURE MEDICINE (2001)
Isotype-dependent inhibition of tumor growth in vivo by monoclonal antibodies to death receptor 4
A Chuntharapai et al.
JOURNAL OF IMMUNOLOGY (2001)
FADD is required for DR4-and DR5-mediated apoptosis - Lack of trail-induced apoptosis in FADD-deficient mouse embryonic fibroblasts
AA Kuang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Temperature-sensitive differential affinity of TRAIL for its receptors - DR5 is the highest affinity receptor
A Truneh et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2
MR Sprick et al.
IMMUNITY (2000)
Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5
FC Kischkel et al.
IMMUNITY (2000)
TRAIL receptor-2 signals apoptosis through FADD and caspase-8
JL Bodmer et al.
NATURE CELL BIOLOGY (2000)
A unique zinc-binding site revealed by a high-resolution X-ray structure of homotrimeric Apo2L/TRAIL
SG Hymowitz et al.
BIOCHEMISTRY (2000)
Share Paper
