Related references
Note: Only part of the references are listed.Mutational analysis of ABC proteins
Tip W. Loo et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2008)
Correctors promote folding of the CFTR in the endoplasmic reticulum
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Suppressor mutations in the transmembrane segments of P-glycoprotein promote maturation of processing mutants and disrupt a subset of drug-binding sites
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Additive effect of multiple pharmacological chaperones on maturation of CFTR processing mutants
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Structure of a bacterial multidrug ABC transporter
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Folding of CFTR is predominantly cotranslational
B Kleizen et al.
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Small-molecule correctors of defective ΔF508-CFTR cellular processing identified by high-throughput screening
N Pedemonte et al.
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Recent progress in understanding the mechanism of P-glycoprotein-mediated drug efflux
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JOURNAL OF MEMBRANE BIOLOGY (2005)
The dileucine motif at the COOH terminus of human multidrug resistance P-glycoprotein is important for folding but not activity
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JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Impact of the ΔF508 mutation in first nucleotide-binding domain of human cystic fibrosis transmembrane conductance regulator on domain folding and structure
HA Lewis et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Disulfide cross-linking analysis shows that transmembrane segments 5 and 8 of human P-glycoprotein are close together on the cytoplasmic side of the membrane
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JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Processing mutations located throughout the human multidrug resistance P-glycoprotein disrupt interactions between the nucleotide binding domains
TW Loo et al.
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Simultaneous binding of two different drugs in the binding pocket of the human multidrug resistance P-glycoprotein
TW Loo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Substrate-induced conformational, changes in the transmembrane segments of human P-glycoprotein - Direct evidence for the substrate-induced fit mechanism for drug binding
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JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
The LSGGQ motif in each nucleotide-binding domain of human P-glycoprotein is adjacent to the opposing Walker A sequence
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Introduction of the most common cystic fibrosis mutation (ΔF508) into human P-glycoprotein disrupts packing of the transmembrane segments
TW Loo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
The E-coli BtuCD structure:: A framework for ABC transporter architecture and mechanism
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SCIENCE (2002)
Vanadate trapping of nucleotide at the ATP-binding sites of human multidrug resistance P-glycoprotein exposes different residues to the drug-binding site
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Cystic fibrosis: A worldwide analysis of CFTR mutations - Correlation with incidence data and application to screening
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