Related references
Note: Only part of the references are listed.Simvastatin inhibits TNFα-induced invasion of human cardiac myofibroblasts via both MMP-9-dependent and -independent mechanisms
Neil A. Turner et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2007)
Silibinin suppresses human osteosarcoma MG-63 cell invasion by inhibiting the ERK-dependent c-Jun/AP-1 induction of MMP-2
Yih-Shou Hsieh et al.
CARCINOGENESIS (2007)
Syndecan-2 affects the basal and chemotherapy-induced apoptosis in osteosarcoma
Armelle Orosco et al.
CANCER RESEARCH (2007)
Gonadotropin-releasing hormone promotes ovarian cancer cell invasiveness through c-jun NH2-terminal kinase -: Mediated activation of matrix metalloproteinase (MMP)-2 and MMP-9
Lydia W. T. Cheung et al.
CANCER RESEARCH (2006)
RhoA GTPase inactivation by statins induces osteosarcoma cell apoptosis by inhibiting p42/p44-MAPKs-Bcl-2 signaling independently of BMP-2 and cell differentiation
O. Fromigue et al.
CELL DEATH AND DIFFERENTIATION (2006)
JNK and PI3K differentially regulate MMP-2 and MT1-MMP mRNA and protein in response to actin cytoskeleton reorganization in endothelial cells
Eric Ispanovic et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2006)
Regulation of matrix metalloproteinase (MMP) gene expression by protein kinases
PM Reuben et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2006)
Elevated levels of cholesterol-rich lipid rafts in cancer cells are correlated with apoptosis sensitivity induced by cholesterol-depleting agents
YC Li et al.
AMERICAN JOURNAL OF PATHOLOGY (2006)
Matrix metalloproteinases and tumor metastasis
EI Deryugina et al.
CANCER AND METASTASIS REVIEWS (2006)
Angiopoietin 2 induces glioma cell invasion by stimulating matrix metalloprotease 2 expression through the αvβ1 integrin and focal adhesion kinase signaling pathway
B Hu et al.
CANCER RESEARCH (2006)
Fos/AP-1 proteins in bone and the immune system
EF Wagner et al.
IMMUNOLOGICAL REVIEWS (2005)
The Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasion
J Pratap et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Matrix metalloproteinases participate in osteosarcoma invasion
K Bjornland et al.
JOURNAL OF SURGICAL RESEARCH (2005)
Hematogenous micrometastases in osteosarcoma patients
OS Bruland et al.
CLINICAL CANCER RESEARCH (2005)
Essential role of RSK2 in c-Fos-dependent osteosarcoma development
JP David et al.
JOURNAL OF CLINICAL INVESTIGATION (2005)
Simvastatin inhibits MMP-9 secretion from human saphenous vein smooth muscle cells by inhibiting the RhoA/ROCK pathway and reducing MMP-9 mRNA levels
NA Turner et al.
FASEB JOURNAL (2005)
Simvastatin, an HMG-CoA reductase inhibitor, reduced the expression of matrix metalloproteinase-9 (Gelatinase B) in osteoblastic cells and HT1080 fibrosarcoma cells
PD Thunyakitpisal et al.
JOURNAL OF PHARMACOLOGICAL SCIENCES (2004)
Distinct roles for JNK1 and JNK2 in regulating JNK activity and c-Jun-dependent cell proliferation
K Sabapathy et al.
MOLECULAR CELL (2004)
Mevalonate promotes the growth of tumors derived from human cancer cells in vivo and stimulates proliferation in vitro with enhanced cyclin-dependent kinase-2 activity
RE Duncan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Tumor necrosis factor α induces human atrial myofibroblast proliferation, invasion and MMP-9 secretion:: inhibition by simvastatin
KE Porter et al.
CARDIOVASCULAR RESEARCH (2004)
Effects of statins and farnesyltransferase inhibitors on the development and progression of cancer
MR Graaf et al.
CANCER TREATMENT REVIEWS (2004)
AP-1: A double-edged sword in tumorigenesis
R Eferl et al.
NATURE REVIEWS CANCER (2003)
Activation of the JNK-AP-1 signal transduction pathway is associated with pathogenesis and progression of human osteosarcomas
DJ Papachristou et al.
BONE (2003)
Molecular mechanism of the anti-cancer activity of cerivastatin, an inhibitor of HMG-CoA reductase, on aggressive human breast cancer cells
C Denoyelle et al.
CELLULAR SIGNALLING (2003)
HMG-CoA reductase inhibitors and the malignant cell: the statin family of drugs as triggers of tumor-specific apoptosis
WWL Wong et al.
LEUKEMIA (2002)
Cancer therapy - Matrix metalloproteinase inhibitors and cancer: Trials and tribulations
LM Coussens et al.
SCIENCE (2002)
New functions for the matrix metalloproteinases in cancer progression
M Egeblad et al.
NATURE REVIEWS CANCER (2002)
Breast cancer cells release factors that induce apoptosis in human bone marrow stromal cells
O Fromigué et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2001)
Cerivastatin, an inhibitor of HMG-CoA reductase, inhibits the signaling pathways involved in the invasiveness and metastatic properties of highly invasive breast cancer cell lines:: an in vitro study
C Denoyelle et al.
CARCINOGENESIS (2001)
Small GTP-binding protein, Rho, both increased and decreased cellular motility, activation of matrix metalloproteinase 2 and invasion of human osteosarcoma cells
Y Matsumoto et al.
JAPANESE JOURNAL OF CANCER RESEARCH (2001)
Jun N-terminal kinase 2 modulates thymocyte apoptosis and T cell activation through c-Jun and nuclear factor of activated T cell (NF-AT)
A Behrens et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Membrane type 1 matrix metalloproteinase-associated degradation of tissue inhibitor of metalloproteinase 2 in human tumor cell lines
E Maquoi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
An orthotopic model of murine osteosarcoma with clonally related variants differing in pulmonary metastatic potential
C Khanna et al.
CLINICAL & EXPERIMENTAL METASTASIS (2000)
Suppression of invasion and MMP-9 expression in NIH 3T3 and v-H-Ras 3T3 fibroblasts by lovastatin through inhibition of gas isoprenylation
IK Wang et al.
ONCOLOGY (2000)