Journal
JOURNAL OF BIOCHEMISTRY
Volume 149, Issue 3, Pages 229-230Publisher
OXFORD UNIV PRESS
DOI: 10.1093/jb/mvq152
Keywords
Angiogenesis; Bone Marrow; Endothelium; FeedbackHematopoiesis
Categories
Ask authors/readers for more resources
Angiogenesis, a formation of neo-vessels from pre-existing ones, is regulated by the local balance between its stimulators and inhibitors. Vasohibin-1 (VASH1) was originally identified as an endothelium-derived vascular endothelial growth factor (VEGF)-inducible angiogenesis inhibitor that acts in a negative feedback manner. The expression of VASH1 has been shown in endothelial cells (ECs) in both physiological and pathological conditions associated with angiogenesis. However, recent reports indicate that VASH1 is expressed not only in ECs but also in other cell types including haematopoietic cells. The function of VASH1 may not be restricted to angiogenesis inhibition.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available