Journal
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 59, Issue 10, Pages 6620-6624Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.01452-15
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Funding
- EvoTAR [HEALTH-F3-2011-2011-123 282004]
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An Enterobacter ludwigii strain was isolated during routine screening of a Japanese patient for carriage of carbapenem-resistant Enterobacteriaceae. PCR analysis revealed the bla(NMC-A) carbapenemase gene. Whole-genome sequencing revealed that bla(NMC-A) was inserted in the chromosome and associated with a novel 29.1-kb putative Xer-dependent integrative mobile element, named EludIMEX-1. Bioinformatic analysis identified similar elements in the genomes of an Enterobacter asburiae strain and of other Enterobacter cloacae complex strains, confirming the mobile nature of this element.
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