Related references
Note: Only part of the references are listed.ATX expression and LPA signalling are vital for the development of the nervous system
Stella Fotopoulou et al.
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Autotaxin/Lysophospholipase D-mediated Lysophosphatidic Acid Signaling Is Required to Form Distinctive Large Lysosomes in the Visceral Endoderm Cells of the Mouse Yolk Sac
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JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
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JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
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AMERICAN JOURNAL OF PATHOLOGY (2008)
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BRITISH JOURNAL OF HAEMATOLOGY (2008)
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LPA1 receptor activation promotes renal interstitial fibrosis
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Plasma lysophosphatidic acid level and serum autotaxin activity are increased in liver injury in rats in relation to its severity
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Functional invalidation of the autotaxin gene by a single amino acid mutation in mouse is lethal
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FEBS LETTERS (2007)
An essential oligomannosidic glycan chain in the catalytic domain of autotaxin, a secreted lysophospholipase-D
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JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Diversified expression patterns of autotaxin, a gene for phospholipid-generating enzyme during mouse and chicken development
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DEVELOPMENTAL DYNAMICS (2007)
Cyclic phosphatidic acid is produced by autotaxin in blood
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JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Autotaxin stabilizes blood vessels and is required for embryonic vasculature by producing lysophosphatidic acid
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GPR92 as a new G12/13- and Gq-coupled lysophosphatidic acid receptor that increases cAMP, LPA5
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Lysophosphatidic acid binds to and activates GPR92, a G protein-coupled receptor highly expressed in gastrointestinal lymphocytes
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Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during development
Laurens A. van Meeteren et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Autotaxin is overexpressed in glioblastoma multiforme and contributes to cell motility of glioblastoma by converting lysophosphatidylcholine TO lysophosphatidic acid
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JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Fluorogenic phospholipid substrate to detect lysophospholipase D/autotaxin activity
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The N-terminal hydrophobic sequence of autotaxin (ENPP2) functions as a signal peptide
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Lysophosphatidic acid inhibits cholera toxin-induced secretory diarrhea through CFTR-dependent protein interactions
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Induction of autotaxin by the Epstein-Barr virus promotes the growth and survival of Hodgkin lymphoma cells
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Proteolytic maturation and activation of autotaxin (NPP2), a secreted metastasis-enhancing lysophospholipase D
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Biochemical and molecular characterization of a novel choline-specific glycerophosphodiester phosphodiesterase belonging to the nucleotide pyrophosphatase/phosphodiesterase family
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Inhibition of autotaxin by lysophosphatidic acid and sphingosine 1-phosphate
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JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
LPA3-mediated lysophosphatidic acid signalling in embryo implantation and spacing
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Lysophosphatidic acid inhibits adipocyte differentiation via lysophosphatidic acid 1 receptor-dependent down-regulation of peroxisome proliferator-activated receptor γ2
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Phosphodieterase-Iα/autotaxin and IFAK phosphorylation during controls cytoskeletal organization myelination
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Thrombogenic and atherogenic activities of lysophosphatidic acid
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Initiation of neuropathic pain requires lysophosphatidic acid receptor signaling
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Proteomic analysis of multiple sclerosis cerebrospinal fluid
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Expression, regulation and function of autotaxin in thyroid carcinomas
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INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY (2004)
Vascular remodeling induced by naturally occurring unsaturated lysophosphatidic acid in vivo
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Identification of human intestinal alkaline sphingomyelinase as a novel ecto-enzyme related to the nucleotide phosphodiesterase family
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JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Characterization of nucleotide pyrophosphatase-5 as an oligomannosidic glycoprotein in rat brain
Y Ohe et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
The emerging role of lysophosphatidic acid in cancer
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Identification of p2y9/GPR23 as a novel G protein-coupled receptor for lysophosphatidic acid, structurally distant from the Edg family
K Noguchi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Autotaxin is released from adipocytes, catalyzes lysophosphatidic acid synthesis, and activates preadipocyte proliferation -: Up-regulated expression with adipocyte differentiation and obesity
G Ferry et al.
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Insulin modulates PC-1 processing and recruitment in cultured human cells
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Identification of an intracellular receptor for lysophosphatidic acid (LPA):: LPA is a transcellular PPARγ agonist
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Non-proliferative effects of lysophosphatidic acid enhance cortical growth and folding
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Serum lysophosphatidic acid is produced through diverse phospholipase pathways
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Increased production of bioactive lysophosphatidic acid by serum lysophospholipase D in human pregnancy
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BIOLOGY OF REPRODUCTION (2002)
Identification of human plasma lysophospholipase D, a lysophosphatidic acid-producing enzyme, as autotaxin, a multifunctional phosphodiesterase
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JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Characterization of lpa2 (Edg4) and lpa1/lpa2 (Edg2/Edg4) lysophosphatidic acid receptor knockout mice:: Signaling deficits without obvious phenotypic abnormality attributable to lpa2
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MOLECULAR AND CELLULAR BIOLOGY (2002)
A novel phosphatidic acid-selective phospholipase A1 that produces lysophosphatidic acid
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JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production
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Identification of human renal cell carcinoma associated genes by suppression subtractive hybridization
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Genetic basis of human breast cancer metastasis
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Enzymatic activation of autotaxin by divalent cations without EF-hand loop region involvement
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Endothelial differentiation gene-2 receptor is involved in lysophosphatidic acid-dependent control of 3T3F442A preadipocyte proliferation and spreading
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JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Structural and catalytic similarities between nucleotide pyrophosphatases/phosphodiesterases and alkaline phosphatases
R Gijsbers et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
IL-1 beta- and IL-4-induced down-regulation of autotaxin mRNA and PC-1 in fibroblast-like synoviocytes of patients with rheumatoid arthritis (RA)
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CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2001)
Requirement for the IpA1 lysophosphatidic acid receptor gene in normal suckling behavior
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Lysophosphatidic acid (LPA) receptors of the EDG family are differentially activated by LPA species - Structure-activity relationship of cloned LPA receptors
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