Related references
Note: Only part of the references are listed.PART, a distinct tauopathy, different from classical sporadic Alzheimer disease
Kurt A. Jellinger et al.
ACTA NEUROPATHOLOGICA (2015)
Reactive microglia drive tau pathology and contribute to the spreading of pathological tau in the brain
Nicole Maphis et al.
BRAIN (2015)
NH2-truncated human tau induces deregulated mitophagy in neurons by aberrant recruitment of Parkin and UCHL-1: implications in Alzheimer's disease
V. Corsetti et al.
HUMAN MOLECULAR GENETICS (2015)
Dysregulation of microRNA-219 promotes neurodegeneration through post-transcriptional regulation of tau
Ismael Santa-Maria et al.
JOURNAL OF CLINICAL INVESTIGATION (2015)
Antibody against early driver of neurodegeneration cis P-tau blocks brain injury and tauopathy
Asami Kondo et al.
NATURE (2015)
Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits
Sang-Won Min et al.
NATURE MEDICINE (2015)
Tau post-translational modifications in wild-type and human amyloid precursor protein transgenic mice
Meaghan Morris et al.
NATURE NEUROSCIENCE (2015)
Spreading of pathology in neurodegenerative diseases: a focus on human studies
Johannes Brettschneider et al.
NATURE REVIEWS NEUROSCIENCE (2015)
Intracerebral injection of preformed synthetic tau fibrils initiates widespread tauopathy and neuronal loss in the brains of tau transgenic mice
Eve Peeraer et al.
NEUROBIOLOGY OF DISEASE (2015)
Tau stabilizes microtubules by binding at the interface between tubulin heterodimers
Harindranath Kadavath et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Role of the Tau N-terminal region in microtubule stabilization revealed by new endogenous truncated forms
Maxime Derisbourg et al.
SCIENTIFIC REPORTS (2015)
Pro-aggregant Tau impairs mossy fiber plasticity due to structural changes and Ca++ dysregulation
Jochen Martin Decker et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2015)
Preventive methylene blue treatment preserves cognition in mice expressing full-length pro-aggregant human Tau
Katja Hochgraefe et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2015)
Tau Monoclonal Antibody Generation Based on Humanized Yeast Models IMPACT ON TAU OLIGOMERIZATION AND DIAGNOSTICS
Joelle Rosseels et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Peripheral administration of tau aggregates triggers intracerebral tauopathy in transgenic mice
Florence Clavaguera et al.
ACTA NEUROPATHOLOGICA (2014)
Novel mutation in MAPT exon 13 (p.N410H) causes corticobasal degeneration
Naomi Kouri et al.
ACTA NEUROPATHOLOGICA (2014)
Are cases with tau pathology occurring in the absence of Aβ deposits part of the AD-related pathological process?
Heiko Braak et al.
ACTA NEUROPATHOLOGICA (2014)
Primary age-related tauopathy (PART): a common pathology associated with human aging
John F. Crary et al.
ACTA NEUROPATHOLOGICA (2014)
Tau Reduction Prevents Disease in a Mouse Model of Dravet Syndrome
Ania L. Gheyara et al.
ANNALS OF NEUROLOGY (2014)
Myelination of the Nervous System: Mechanisms and Functions
Klaus-Armin Nave et al.
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 30 (2014)
Lysine methylation is an endogenous post-translational modification of tau protein in human brain and a modulator of aggregation propensity
Kristen E. Funk et al.
BIOCHEMICAL JOURNAL (2014)
Neuronal uptake of tau/pS422 antibody and reduced progression of tau pathology in a mouse model of Alzheimer's disease
Ludovic Collin et al.
BRAIN (2014)
Hsp90-Tau Complex Reveals Molecular Basis for Specificity in Chaperone Action
G. Elif Karagoz et al.
CELL (2014)
Targeting Hsp90 and its co-chaperones to treat Alzheimer's disease
Laura J. Blair et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2014)
Acetylation of the KXGS motifs in tau is a critical determinant in modulation of tau aggregation and clearance
Casey Cook et al.
HUMAN MOLECULAR GENETICS (2014)
Extracellular Monomeric Tau Protein Is Sufficient to Initiate the Spread of Tau Protein Pathology
Claire H. Michel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Alternative Conformations of the Tau Repeat Domain in Complex with an Engineered Binding Protein
Clara S. R. Gruening et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
RNA Protein Granules Modulate tau Isoform Expression and Induce Neuronal Sprouting
Katharina Moschner et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Prion-like Properties of Tau Protein: The Importance of Extracellular Tau as a Therapeutic Target
Brandon B. Holmes et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Oligomer Formation of Tau Protein Hyperphosphorylated in Cells
Katharina Tepper et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Neuronal activity regulates extracellular tau in vivo
Kaoru Yamada et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2014)
O-GIcNAc Modification of tau Directly Inhibits Its Aggregation without Perturbing the Conformational Properties of tau Monomers
Scott A. Yuzwa et al.
JOURNAL OF MOLECULAR BIOLOGY (2014)
Activity-Dependent Tau Protein Translocation to Excitatory Synapse Is Disrupted by Exposure to Amyloid-Beta Oligomers
Marie Lise Frandemiche et al.
JOURNAL OF NEUROSCIENCE (2014)
Passive Immunization with Tau Oligomer Monoclonal Antibody Reverses Tauopathy Phenotypes without Affecting Hyperphosphorylated Neurofibrillary Tangles
Diana L. Castillo-Carranza et al.
JOURNAL OF NEUROSCIENCE (2014)
Proteostasis and the Aging Proteome in Health and Disease
Richard I. Morimoto et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2014)
Davunetide in patients with progressive supranuclear palsy: a randomised, double-blind, placebo-controlled phase 2/3 trial
Adam L. Boxer et al.
LANCET NEUROLOGY (2014)
Motor and cognitive deficits in aged tau knockout mice in two background strains
Peng Lei et al.
MOLECULAR NEURODEGENERATION (2014)
Tideglusib reduces progression of brain atrophy in progressive supranuclear palsy in a randomized trial
Guenter U. Hoeglinger et al.
MOVEMENT DISORDERS (2014)
Huntington's disease is a four-repeat tauopathy with tau nuclear rods
Marta Fernandez-Nogales et al.
NATURE MEDICINE (2014)
Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer's disease
Zhentao Zhang et al.
NATURE MEDICINE (2014)
Cognition and hippocampal synaptic plasticity in mice with a homozygous tau deletion
Tariq Ahmed et al.
NEUROBIOLOGY OF AGING (2014)
Tau Immunotherapy and Imaging
Einar M. Sigurdsson
NEURODEGENERATIVE DISEASES (2014)
Distinct Tau Prion Strains Propagate in Cells and Mice and Define Different Tauopathies
David W. Sanders et al.
NEURON (2014)
Mitochondrial Complex 1 Inhibition Increases 4-Repeat Isoform Tau by SRSF2 Upregulation
Julius Bruch et al.
PLOS ONE (2014)
Microtubule-associated protein tau is essential for long-term depression in the hippocampus
Tetsuya Kimura et al.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2014)
SUMOylation at K340 inhibits tau degradation through deregulating its phosphorylation and ubiquitination
Hong-Bin Luo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Immunophilin FKBP52 induces Tau-P301L filamentous assembly in vitro and modulates its activity in a model of tauopathy
Julien Giustiniani et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
A major role for Tau in neuronal DNA and RNA protection in vivo under physiological and hyperthermic conditions
Marie Violet et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2014)
Open questions for Alzheimer's disease immunotherapy
Todd E. Golde
ALZHEIMERS RESEARCH & THERAPY (2014)
Acetylated Tau Neuropathology in Sporadic and Hereditary Tauopathies
David J. Irwin et al.
AMERICAN JOURNAL OF PATHOLOGY (2013)
Amyloid-β oligomers induce synaptic damage via Tau-dependent microtubule severing by TTLL6 and spastin
Hans Zempel et al.
EMBO JOURNAL (2013)
Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?
James A. Nathan et al.
EMBO JOURNAL (2013)
Physiological release of endogenous tau is stimulated by neuronal activity
Amy M. Pooler et al.
EMBO REPORTS (2013)
Mitochondrial defects and oxidative stress in Alzheimer disease and Parkinson disease
Michael H. Yan et al.
FREE RADICAL BIOLOGY AND MEDICINE (2013)
Antibody Uptake into Neurons Occurs Primarily via Clathrin-dependent Fcγ Receptor Endocytosis and Is a Prerequisite for Acute Tau Protein Clearance
Erin E. Congdon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Amyloid-β signals through tau to drive ectopic neuronal cell cycle re-entry in Alzheimer's disease
Matthew E. Seward et al.
JOURNAL OF CELL SCIENCE (2013)
Therapeutic strategies for tau mediated neurodegeneration
Yasumasa Yoshiyama et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2013)
Tau Loss Attenuates Neuronal Network Hyperexcitability in Mouse and Drosophila Genetic Models of Epilepsy
Jerrah K. Holth et al.
JOURNAL OF NEUROSCIENCE (2013)
Antisense Reduction of Tau in Adult Mice Protects against Seizures
Sarah L. DeVos et al.
JOURNAL OF NEUROSCIENCE (2013)
The microtubule-associated tau protein has intrinsic acetyltransferase activity
Todd J. Cohen et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2013)
Anti-Tau Antibodies that Block Tau Aggregate Seeding In Vitro Markedly Decrease Pathology and Improve Cognition In Vivo
Kiran Yanamandra et al.
NEURON (2013)
Rapamycin Attenuates the Progression of Tau Pathology in P301S Tau Transgenic Mice
Sefika Ozcelik et al.
PLOS ONE (2013)
Tau Passive Immunotherapy in Mutant P301L Mice: Antibody Affinity versus Specificity
Cristina d'Abramo et al.
PLOS ONE (2013)
Profiling Murine Tau with 0N, 1N and 2N Isoform-Specific Antibodies in Brain and Peripheral Organs Reveals Distinct Subcellular Localization, with the 1N Isoform Being Enriched in the Nucleus
Chang Liu et al.
PLOS ONE (2013)
The fuzzy coat of pathological human Tau fibrils is a two-layered polyelectrolyte brush
Susanne Wegmann et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds
Brandon B. Holmes et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Selective tau tyrosine nitration in non-AD tauopathies
Juan F. Reyes et al.
ACTA NEUROPATHOLOGICA (2012)
Cognitive defects are reversible in inducible mice expressing pro-aggregant full-length human Tau
Ann Van der Jeugd et al.
ACTA NEUROPATHOLOGICA (2012)
Lack of Tau Proteins Rescues Neuronal Cell Death and Decreases Amyloidogenic Processing of APP in APP/PS1 Mice
Karelle Leroy et al.
AMERICAN JOURNAL OF PATHOLOGY (2012)
Degradation of tau protein by autophagy and proteasomal pathways
Yipeng Wang et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2012)
Loss of fused in sarcoma (FUS) promotes pathological Tau splicing
Denise Orozco et al.
EMBO REPORTS (2012)
Identification of oligomers at early stages of tau aggregation in Alzheimer's disease
Cristian A. Lasagna-Reeves et al.
FASEB JOURNAL (2012)
MAPT expression and splicing is differentially regulated by brain region: relation to genotype and implication for tauopathies
Daniah Trabzuni et al.
HUMAN MOLECULAR GENETICS (2012)
Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimers diseases
Giovanni Coppola et al.
HUMAN MOLECULAR GENETICS (2012)
Inhibition of tau aggregation in a novel Caenorhabditis elegans model of tauopathy mitigates proteotoxicity
Chronis Fatouros et al.
HUMAN MOLECULAR GENETICS (2012)
Interaction of Endogenous Tau Protein with Synaptic Proteins Is Regulated by N-Methyl-D-aspartate Receptor-dependent Tau Phosphorylation
Siddhartha Mondragon-Rodriguez et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Tau Isoform Composition Influences Rate and Extent of Filament Formation
Qi Zhong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Tau Oligomers Impair Artificial Membrane Integrity and Cellular Viability
Katharina Flach et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Extracellular Tau Levels Are Influenced by Variability in Tau That Is Associated with Tauopathies
Celeste M. Karch et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export
Peng Lei et al.
NATURE MEDICINE (2012)
Autophagic degradation of tau in primary neurons and its enhancement by trehalose
Ulrike Krueger et al.
NEUROBIOLOGY OF AGING (2012)
Biochemistry and Cell Biology of Tau Protein in Neurofibrillary Degeneration
Eva-Maria Mandelkow et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2012)
Novel diffusion barrier for axonal retention of Tau in neurons and its failure in neurodegeneration
Xiaoyu Li et al.
EMBO JOURNAL (2011)
MicroRNA-132 loss is associated with tau exon 10 inclusion in progressive supranuclear palsy
Pascal Y. Smith et al.
HUMAN MOLECULAR GENETICS (2011)
Nuclear Tau, a Key Player in Neuronal DNA Protection
Audrey Sultan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Seeding of Normal Tau by Pathological Tau Conformers Drives Pathogenesis of Alzheimer-like Tangles
Jing L. Guo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Neuropathology of Frontotemporal Lobar Degeneration-Tau (FTLD-Tau)
Dennis W. Dickson et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2011)
Pathogenic Forms of Tau Inhibit Kinesin-Dependent Axonal Transport through a Mechanism Involving Activation of Axonal Phosphotransferases
Nicholas M. Kanaan et al.
JOURNAL OF NEUROSCIENCE (2011)
Tau-Induced Defects in Synaptic Plasticity, Learning, and Memory Are Reversible in Transgenic Mice after Switching Off the Toxic Tau Mutant
Astrid Sydow et al.
JOURNAL OF NEUROSCIENCE (2011)
In Vivo Microdialysis Reveals Age-Dependent Decrease of Brain Interstitial Fluid Tau Levels in P301S Human Tau Transgenic Mice
Kaoru Yamada et al.
JOURNAL OF NEUROSCIENCE (2011)
Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation
Stuart A. Sievers et al.
NATURE (2011)
Cleavage of Tau by calpain in Alzheimer's disease: the quest for the toxic 17 kD fragment
Sarika Garg et al.
NEUROBIOLOGY OF AGING (2011)
Post-translational modifications of tau protein: Implications for Alzheimer's disease
Ludovic Martin et al.
NEUROCHEMISTRY INTERNATIONAL (2011)
Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models
Lars M. Ittner et al.
CELL (2010)
Essential Role of Tau Phosphorylation in Adult Hippocampal Neurogenesis
Xiao-Ping Hong et al.
HIPPOCAMPUS (2010)
Epothilone D Improves Microtubule Density, Axonal Integrity, and Cognition in a Transgenic Mouse Model of Tauopathy
Kurt R. Brunden et al.
JOURNAL OF NEUROSCIENCE (2010)
Aβ Oligomers Cause Localized Ca2+ Elevation, Missorting of Endogenous Tau into Dendrites, Tau Phosphorylation, and Destruction of Microtubules and Spines
Hans Zempel et al.
JOURNAL OF NEUROSCIENCE (2010)
Caspase activation precedes and leads to tangles
Alix de Calignon et al.
NATURE (2010)
Acetylation of Tau Inhibits Its Degradation and Contributes to Tauopathy
Sang-Won Min et al.
NEURON (2010)
Tau Mislocalization to Dendritic Spines Mediates Synaptic Dysfunction Independently of Neurodegeneration
Brian R. Hoover et al.
NEURON (2010)
Overexpression of Wild-Type Murine Tau Results in Progressive Tauopathy and Neurodegeneration
Stephanie J. Adams et al.
AMERICAN JOURNAL OF PATHOLOGY (2009)
Characteristics and consequences of muscarinic receptor activation by tau protein
Alberto Gomez-Ramos et al.
EUROPEAN NEUROPSYCHOPHARMACOLOGY (2009)
Function of tau protein in adult newborn neurons
Almudena Fuster-Matanzo et al.
FEBS LETTERS (2009)
SUT-2 potentiates tau-induced neurotoxicity in Caenorhabditis elegans
Chris R. Guthrie et al.
HUMAN MOLECULAR GENETICS (2009)
Tau fragmentation, aggregation and clearance: the dual role of lysosomal processing
Yipeng Wang et al.
HUMAN MOLECULAR GENETICS (2009)
Phosphorylated Tau Interacts with c-Jun N-terminal Kinase-interacting Protein 1 (JIP1) in Alzheimer Disease
Lars M. Ittner et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Specification of Neuronal Polarity Regulated by Local Translation of CRMP2 and Tau via the mTOR-p70S6K Pathway
Tsuyoshi Morita et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Activated Actin-Depolymerizing Factor/Cofilin Sequesters Phosphorylated Microtubule-Associated Protein during the Assembly of Alzheimer-Like Neuritic Cytoskeletal Striations
Ineka T. Whiteman et al.
JOURNAL OF NEUROSCIENCE (2009)
Transmission and spreading of tauopathy in transgenic mouse brain
Florence Clavaguera et al.
NATURE CELL BIOLOGY (2009)
Mechanisms of regulated unconventional protein secretion
Walter Nickel et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2009)
Tau phosphorylation: the therapeutic challenge for neurodegenerative disease
Diane P. Hanger et al.
TRENDS IN MOLECULAR MEDICINE (2009)
Structural Polymorphism of 441-Residue Tau at Single Residue Resolution
Marco D. Mukrasch et al.
PLOS BIOLOGY (2009)
Phosphorylation regulates tau interactions with Src homology 3 domains of phosphatidylinositol 3-kinase, phospholipase Cγ1, Grb2, and Src family kinases
C. Hugh Reynolds et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
I1PP2A affects Tau phosphorylation via association with the catalytic subunit of protein phosphatase 2A
She Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
In vivo imaging reveals dissociation between caspase activation and acute neuronal death in tangle-bearing neurons
Tara L. Spires-Jones et al.
JOURNAL OF NEUROSCIENCE (2008)
The potential for β-structure in the repeat domain of Tau protein determines aggregation, synaptic decay, neuronal loss, and coassembly with endogenous Tau in inducible mouse models of tauopathy
Maria-Magdalena Mocanu et al.
JOURNAL OF NEUROSCIENCE (2008)
Axonal transport rates in vivo are unaffected by tau deletion or overexpression in mice
Aidong Yuan et al.
JOURNAL OF NEUROSCIENCE (2008)
Two motifs within the tau microtubule-binding domain mediate its association with the hsc70 molecular chaperone
Mitul Sarkar et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2008)
Extracellular tau promotes intracellular calcium increase through M1 and M3 muscarinic receptors in neuronal cells
A. Gomez-Ramos et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2008)
Differential regulation of dynein and kinesin motor proteins by tau
Ram Dixit et al.
SCIENCE (2008)
Interaction of tau protein with the dynactin complex
Enrico Magnani et al.
EMBO JOURNAL (2007)
The β-propensity of Tau determines aggregation and synaptic loss in inducible mouse models of tauopathy
Katrin Eckermann et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Swimming against the tide: Mobility of the microtubule-associated protein tau in neurons
Sven Konzack et al.
JOURNAL OF NEUROSCIENCE (2007)
Immunotherapy targeting pathological tau conformers in a tangle mouse model reduces brain pathology with associated functional improvements
Ayodeji A. Asuni et al.
JOURNAL OF NEUROSCIENCE (2007)
SUT-1 enables tau-induced neurotoxicity in C-elegans
Brian C. Kraemer et al.
HUMAN MOLECULAR GENETICS (2007)
Stepwise proteolysis liberates tau fragments that nucleate the Alzheimer-like aggregation of full-length tau in a neuronal cell model
Y. P. Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Reducing endogenous tau ameliorates amyloid β-induced deficits in an Alzheimer's disease mouse model
Erik D. Roberson et al.
SCIENCE (2007)
Granular tau oligomers as intermediates of tau filaments
Sumihiro Maeda et al.
BIOCHEMISTRY (2007)
Anesthesia leads to tau hyperphosphorylation through inhibition of phosphatase activity by hypothermia
Emmanuel Planel et al.
JOURNAL OF NEUROSCIENCE (2007)
Missorting of tau in neurons causes degeneration of synapses that can be rescued by the kinase MARK2/Par-1
Edda Thies et al.
JOURNAL OF NEUROSCIENCE (2007)
The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteins
Chad A. Dickey et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Abnormal bundling and accumulation of F-actin mediates tau-induced neuronal degeneration in vivo
Tudor A. Fulga et al.
NATURE CELL BIOLOGY (2007)
Multiple-motor based transport and its regulation by Tau
Michael Vershinin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
A beta Oligomers - a decade of discovery
Dominic M. Walsh et al.
JOURNAL OF NEUROCHEMISTRY (2007)
Molecular anatomy of a trafficking organelle
Shigeo Takamori et al.
CELL (2006)
Truncated tau from sporadic Alzheimer's disease suffices to drive neurofibrillary degeneration in vivo
Norbert Zilka et al.
FEBS LETTERS (2006)
Polymerization of hyperphosphorylated tau into filaments eliminates its inhibitory activity
Alejandra Del C. Alonso et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Tau protein binds to pericentromeric DNA:: a putative role for nuclear tau in nucleolar organization
Marcela K. Sjoberg et al.
JOURNAL OF CELL SCIENCE (2006)
Pseudophosphorylation of tau at serine 422 inhibits caspase cleavage:: in vitro evidence and implications for tangle formation in vivo
AL Guillozet-Bongaarts et al.
JOURNAL OF NEUROCHEMISTRY (2006)
Small ubiquitin-like modifier (SUMO) modification of natively unfolded proteins tau and α-synuclein
V Dorval et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Global hairpin folding of tau in solution
S Jeganathan et al.
BIOCHEMISTRY (2006)
Rapamycin alleviates toxicity of different aggregate-prone proteins
Z Berger et al.
HUMAN MOLECULAR GENETICS (2006)
Inducible expression of tau repeat domain in cell models of tauopathy - Aggregation is toxic to cells but can be reversed by inhibitor drugs
I Khlistunova et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Disease-related modifications in tau affect the interaction between Fyn and tau
K Bhaskar et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Molecular motors implicated in the axonal transport of tau and α-synuclein
MA Utton et al.
JOURNAL OF CELL SCIENCE (2005)
Increase in tau tyrosine phosphorylation correlates with the formation of tau aggregates
IE Vega et al.
MOLECULAR BRAIN RESEARCH (2005)
Tau suppression in a neurodegenerative mouse model improves memory function
K SantaCruz et al.
SCIENCE (2005)
Sequestosome 1/p62 shuttles polyubiquitinated tau for proteasomal degradation
JR Babu et al.
JOURNAL OF NEUROCHEMISTRY (2005)
Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms
C Andorfer et al.
JOURNAL OF NEUROSCIENCE (2005)
Inability of tau to properly regulate neuronal microtubule dynamics: a loss-of-function mechanism by which tau might mediate neuronal cell death
SC Feinstein et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2005)
CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation
L Petrucelli et al.
HUMAN MOLECULAR GENETICS (2004)
Alterations in glucose metabolism induce hypothermia leading to tau hyperphosphorylation through differential inhibition of kinase and phosphatase activities: Implications for Alzheimer's disease
E Planel et al.
JOURNAL OF NEUROSCIENCE (2004)
Zeta 14-3-3 protein favours the formation of human tau fibrillar polymers
F Hernández et al.
NEUROSCIENCE LETTERS (2004)
CHIP-Hsc70 complex ubiquitinates phosphorylated tau and enhances cell survival
H Shimura et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Molecular aging of tau:: disulfide-independent aggregation and non-enzymatic degradation in vitro and in vivo
A Watanabe et al.
JOURNAL OF NEUROCHEMISTRY (2004)
O-GlcNAcylation regulates phosphorylation of tau: A mechanism involved in Alzheimer's disease
F Liu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Expression of tau mRNA and soluble tau isoforms in affected and non-affected brain areas in Alzheimer's disease
A Boutajangout et al.
FEBS LETTERS (2004)
Downregulation of protein phosphatase 2A carboxyl methylation and methyltransferase may contribute to Alzheimer disease pathogenesis
E Sontag et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2004)
Triple-transgenic model of Alzheimer's disease with plaques and tangles:: Intracellular Aβ and synaptic dysfunction
S Oddo et al.
NEURON (2003)
Isoforms changes of tau protein during development in various species
H Takuma et al.
DEVELOPMENTAL BRAIN RESEARCH (2003)
SUMO-1 marks the nuclear inclusions in familial neuronal intranuclear inclusion disease
DL Pountney et al.
EXPERIMENTAL NEUROLOGY (2003)
Protein kinase MARK/PAR-1 is required for neurite outgrowth and establishment of neuronal polarity
J Biernat et al.
MOLECULAR BIOLOGY OF THE CELL (2002)
Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress
K Stamer et al.
JOURNAL OF CELL BIOLOGY (2002)
Aberrant glycosylation modulates phosphorylation of tau by protein kinase A and dephosphorylation of tau by protein phosphatase 2A and 5
F Liu et al.
NEUROSCIENCE (2002)
Hyperphosphorylation induces self-assembly of τ into tangles of paired helical filaments/straight filaments
AD Alonso et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Neurodegenerative tauopathies
VMY Lee et al.
ANNUAL REVIEW OF NEUROSCIENCE (2001)
Structure, microtubule interactions, and paired helical filament aggregation by tau mutants of frontotemporal dementias
S Barghorn et al.
BIOCHEMISTRY (2000)
Assembly of τ protein into Alzheimer paired helical filaments depends on a local sequence motif (306VQIVYK311) forming β structure
M von Bergen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Share Paper
