Journal
JOURNAL OF BACTERIOLOGY
Volume 193, Issue 11, Pages 2888-2889Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JB.00321-11
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Funding
- Bundesministerium fur Bildung und Forschung [0313801 l]
- Stiftung Rheinland Pfalz fur Innovation [15202-38 62 61/580]
- EU [LSHB-CT-2005-512061, PREVIS LSHM-CT-2003-503413]
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Streptococcus oralis, a commensal species of the human oral cavity, belongs to the Mitis group of streptococci, which includes one of the major human pathogens as well, S. pneumoniae. We report here the first complete genome sequence of this species. S. oralis Uo5, a high-level penicillin- and multiple-antibiotic-resistant isolate from Hungary, is competent for genetic transformation under laboratory conditions. Comparative and functional genomics of Uo5 will be important in understanding the evolution of pathogenesis among Mitis streptococci and their potential to engage in interspecies gene transfer.
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