Journal
JOURNAL OF BACTERIOLOGY
Volume 193, Issue 3, Pages 768-773Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JB.01196-10
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Funding
- NSF [CBET 0846453]
- NIH [R01 GM089999]
- Bartoszek Fund for Basic Biological Science
- Direct For Biological Sciences
- Div Of Molecular and Cellular Bioscience [1121916] Funding Source: National Science Foundation
- Directorate For Engineering
- Div Of Chem, Bioeng, Env, & Transp Sys [0846453] Funding Source: National Science Foundation
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AI-2 is an autoinducer made by many bacteria. LsrB binds AI-2 in the periplasm, and Tsr is the L-serine chemoreceptor. We show that AI-2 strongly attracts Escherichia coli. Both LsrB and Tsr are necessary for sensing AI-2, but AI-2 uptake is not, suggesting that LsrB and Tsr interact directly in the periplasm.
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