Journal
JOURNAL OF BACTERIOLOGY
Volume 192, Issue 7, Pages 2009-2012Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JB.01685-09
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Funding
- Consejo Nacional de Ciencia y Tecnolog a (CONACyT) [37342-N]
- DGAPA-PAPIIT [IN221106/17]
- UNAM
- International Centre for Genetic Engineering and Biotechnology (ICGEB) [CRP/MEX08-02]
- National Institutes of Health [R01 GM059969]
- University of Florida CRIS [FLA-MCS004949]
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The two-component signal transduction system (TCS) BarA/UvrY activates transcription of CsrB and CsrC noncoding RNAs, which act by sequestering the RNA-binding global regulatory protein CsrA. Here, we show that the metabolic end products formate and acetate provide a physiological stimulus for this TCS and thus link posttranscriptional regulation by the Csr system to the metabolic state of the cell.
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