Journal
JOURNAL OF BACTERIOLOGY
Volume 192, Issue 23, Pages 6291-6294Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JB.00644-10
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Funding
- Israel Science Foundation [611/10]
- Binational Science Foundation [2009218]
- German-Israel Foundation [2061/2009]
- Marie Curie International Reintegration grants [PIRG-GA-2009-256340, GA-2010-266717]
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We show that phage lysogenization, lysogens, and prophage induction are all targeted by CRISPR. The results demonstrate that genomic DNA is not immune to the CRISPR system, that the CRISPR system does not require noncytoplasmic elements, and that the system protects from phages entering and exiting the lysogenic cycle.
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