Journal
JOURNAL OF BACTERIOLOGY
Volume 192, Issue 3, Pages 888-892Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JB.01255-09
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Funding
- Wellcome Trust
- Guy's and St. Thomas' Charity
- Department of Health via the NIHR comprehensive Biomedical Research Centre
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The 3.1-Mb genome of an outbreak methicillin-resistant Staphylococcus aureus (MRSA) strain (TW20) contains evidence of recently acquired DNA, including two large regions ( 635 kb and 127 kb). The strain is resistant to a wide range of antibiotics, antiseptics, and heavy metals due to resistance genes encoded on mobile genetic elements and also mutations in housekeeping genes.
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