Journal
JOURNAL OF BACTERIOLOGY
Volume 192, Issue 4, Pages 1160-1164Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JB.01374-09
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- University of Groningen GBB bursary
- University of Groningen Rosalind Franklin
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Overexpression of antisense chromosomal cis-encoded noncoding RNAss (ncRNAs) in glutamine synthetase I resulted in a decrease in growth, protein synthesis, and antibiotic production in Streptomyces coelicolor. In addition, we predicted 3,597 cis-encoded ncRNAs and validated 13 of them experimentally, including several ncRNAs that are differentially expressed in bacterial hormone-defective mutants.
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