4.4 Article

Functional Analysis of Insertion Sequence ISAba1, Responsible for Genomic Plasticity of Acinetobacter baumannii

Journal

JOURNAL OF BACTERIOLOGY
Volume 191, Issue 7, Pages 2414-2418

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/JB.01258-08

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Funding

  1. Ministere de l'Education Nationale et de la Recherche, Universite Paris XI, France
  2. European Community [LSHM-CT2005- 018705]
  3. INSERM, France

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ISAba1 is an insertion sequence that is widely distributed in Acinetobacter baumannii. We demonstrated here that ISAba1 and the composite transposon Tn2006 are capable of transposition, generating 9-bp target site duplications. The expression of the ISAba1 transposase-encoding gene was downregulated by translational frameshifting.

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