Journal
JOURNAL OF BACTERIOLOGY
Volume 192, Issue 3, Pages 896-900Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JB.01122-09
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Funding
- European Commission [LSHG-CT-2004-503468]
- Centre National de la Recherche Scientifique (CNRS) [URA 2172]
- Institut Pasteur [GPH 9]
- English Society of Applied Microbiology (SfAM)
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Lactobacillus plantarum ctsR was characterized. ctsR was found to be cotranscribed with clpC and induced in response to various abiotic stresses. ctsR deletion conferred a heat-sensitive phenotype with peculiar cell morphological features. The transcriptional pattern of putative CtsR regulon genes was examined in the Delta ctsR mutant. Direct CtsR-dependent regulation was demonstrated by DNA-binding assays using recombinant CtsR and the promoters of the ctsR-clpC operon and hsp1.
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