Journal
JOURNAL OF BACTERIOLOGY
Volume 192, Issue 3, Pages 893-895Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JB.01220-09
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Funding
- Spanish Ministry of Science and Innovation (MCINN) [BIO2007-67457-CO2, CSD2008-00013]
- European Regional Fund
- Weissman Fellowship from Harvard University, Cambridge, MA
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The damX gene product of Salmonella enterica serovar Typhimurium is a protein located in the inner membrane. DamX migrates as a 70-kDa protein in SDS-PAGE even though the predicted protein size is 46 kDa. Synthesis of DamX protein occurs in both exponential- and stationary-phase cultures. Disruption of damX causes severe sensitivity to bile. Lack of the outer membrane protein AsmA suppresses bile sensitivity in Salmonella damX mutants.
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