Journal
JOURNAL OF BACTERIOLOGY
Volume 191, Issue 18, Pages 5845-5848Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JB.00294-09
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Funding
- National Institutes of Health [GM062044]
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Specific CheA-short (CheA(S)) residues, L123 and L126, were identified as critical for CheZ binding. In the CheAS 'P1-CheZ nuclear magnetic resonance structure, these residues form an interaction surface on alpha-helix E in the 'P1 domain. Both L123 and L126 are buried in CheA-long (CheA(L)), providing an explanation for why CheA(L) fails to bind CheZ.
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