Journal
JOURNAL OF BACTERIOLOGY
Volume 191, Issue 10, Pages 3424-3428Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JB.01113-08
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Funding
- Japan Society for the Promotion of Science [16658020, 17380031]
- Grants-in-Aid for Scientific Research [17380031, 16658020] Funding Source: KAKEN
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PhcA positively and negatively regulates many genes responsible for pathogenicity of Ralstonia solanacearum. The type III secretion system-encoding hrp regulon is one of the negatively controlled operons. PhcA bound to the promoter region of prhIR and repressed its expression, demonstrating that PhcA shuts down the most upstream component of a signal transfer system for hrpB activation.
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